Creating Efficient and Sustainable Workflows for Scholarly Works into a DSpace Repository

In fall 2017, a team at UH Libraries piloted an expanded set of repository services, including mediated submission of faculty and student works and faculty self-submissions. The Metadata and Digitization Services department worked closely with Digital Research Services to create and implement new workflows for the batch processing and upload of faculty and student research into the UH Institutional Repository. In the 2 month pilot phase, the team added over 650 faculty and student works to the IR and is now scaling up these services.Librarie

Customized CV Service Workflows for DSpace Repositories

Slides for a presentation delivered at the North American DSpace Users Group Meeting at the University of Minnesota-Twin Cities, September 2019. Full workflows and service documentation available at bit.ly/UHoustonCVWorkflows. Conference abstract: The University of Houston Libraries has recently created and implemented workflows for the upload of large batches of faculty research into its DSpace Institutional Repository. These workflows are largely based on modifications made to existing scripts and open source packaging software, and were made possible through collaborative efforts with the Texas Digital Library and other DSpace institutions. This process has involved establishing new in-house metadata procedures and standards, templates for managing and sharing bibliographic data, and divisions of labor. Through the creation of these structured workflows, we have been able to scale our efforts, now employing and training a dedicated team of student employees to carry out this campus-wide service. Over a six-month span, the team has prepared over 1,300 full-text faculty works for ingest into the repository, using faculty CVs as its main source of bibliographic information. This presentation details the challenges and lessons learned from the development and refinement of these end-to-end workflows, as well as a discussion about the broader implications of establishing this option for our faculty researchers. We will package and publicly share all documentation related to this process in hopes that our efforts might inspire wider adoption of these workflows among the DSpace community.Librarie

DSpace

A short review of DSpace, a free, open-source digital repository.Librarie

The IPTA Nashville consensus conference on Post-Transplant lymphoproliferative disorders after solid organ transplantation in children: II-consensus guidelines for prevention

The International Pediatric Transplant Association (IPTA) convened an expert consensus conference to assess current evidence and develop recommendations for various aspects of care relating to post-transplant lymphoproliferative disorder after solid organ transplantation in children. In this report from the Prevention Working Group, we reviewed the existing literature regarding immunoprophylaxis and chemoprophylaxis, and pre-emptive strategies. While the group made a strong recommendation for pre-emptive reduction of immunosuppression at the time of EBV DNAemia (low to moderate evidence), no recommendations for use could be made for any prophylactic strategy or alternate pre-emptive strategy, largely due to insufficient or conflicting evidence. Current gaps and future research priorities are highlighted

The <scp>IPTA</scp> Nashville consensus conference on <scp>post‐transplant</scp> lymphoproliferative disorders after solid organ transplantation in children: <scp>IV</scp>‐consensus guidelines for the management of <scp>post‐transplant</scp> lymphoproliferative disorders in children and adolescents

The International Pediatric Transplant Association convened an expert consensusconference to assess current evidence and develop recommendations for various as-pects of care relating to post-transplant lymphoproliferative disorders (PTLD) afterpediatric solid organ transplantation. This report addresses the outcomes of delib-erations by the PTLD Management Working Group. A strong recommendation wasmade for reduction in immunosuppression as the first step in management. Similarly,strong recommendations were made for the use of the anti-CD20 monoclonal anti-body (rituximab) as was the case for chemotherapy in selected scenarios. In some sce-narios, there is uncoupling of the strength of the recommendations from the availableevidence in situations where such evidence is lacking but collective clinical experi-ences drive decision-making. Of note, there are no large, randomized phase III trials ofany treatment for PTLD in the pediatric age group. Current gaps and future researchpriorities are highlighted

The IPTA Nashville Consensus Conference on Post‐Transplant lymphoproliferative disorders after solid organ transplantation in children: III – Consensus guidelines for Epstein‐Barr virus load and other biomarker monitoring

The International Pediatric Transplant Association convened an expert consensus conference to assess current evidence and develop recommendations for various aspects of care relating to post-transplant lymphoproliferative disorders after solid organ transplantation in children. In this report from the Viral Load and Biomarker Monitoring Working Group, we reviewed the existing literature regarding the role of Epstein-Barr viral load and other biomarkers in peripheral blood for predicting the development of PTLD, for PTLD diagnosis, and for monitoring of response to treatment. Key recommendations from the group highlighted the strong recommendation for use of the term EBV DNAemia instead of "viremia" to describe EBV DNA levels in peripheral blood as well as concerns with comparison of EBV DNAemia measurement results performed at different institutions even when tests are calibrated using the WHO international standard. The working group concluded that either whole blood or plasma could be used as matrices for EBV DNA measurement; optimal specimen type may be clinical context dependent. Whole blood testing has some advantages for surveillance to inform pre-emptive interventions while plasma testing may be preferred in the setting of clinical symptoms and treatment monitoring. However, EBV DNAemia testing alone was not recommended for PTLD diagnosis. Quantitative EBV DNAemia surveillance to identify patients at risk for PTLD and to inform pre-emptive interventions in patients who are EBV seronegative pre-transplant was recommended. In contrast, with the exception of intestinal transplant recipients or those with recent primary EBV infection prior to SOT, surveillance was not recommended in pediatric SOT recipients EBV seropositive pre-transplant. Implications of viral load kinetic parameters including peak load and viral set point on pre-emptive PTLD prevention monitoring algorithms were discussed. Use of additional markers, including measurements of EBV specific cell mediated immunity was discussed but not recommended though the importance of obtaining additional data from prospective multicenter studies was highlighted as a key research priority

The IPTA Nashville consensus conference on Post-Transplant lymphoproliferative disorders after solid organ transplantation in children: II-consensus guidelines for prevention

The International Pediatric Transplant Association (IPTA) convened an expert consensus conference to assess current evidence and develop recommendations for various aspects of care relating to post-transplant lymphoproliferative disorder after solid organ transplantation in children. In this report from the Prevention Working Group, we reviewed the existing literature regarding immunoprophylaxis and chemoprophylaxis, and pre-emptive strategies. While the group made a strong recommendation for pre-emptive reduction of immunosuppression at the time of EBV DNAemia (low to moderate evidence), no recommendations for use could be made for any prophylactic strategy or alternate pre-emptive strategy, largely due to insufficient or conflicting evidence. Current gaps and future research priorities are highlighted