Effect of flameholder pressure drop on emissions and performance of premixed-prevaporized combustors

Parametric tests were conducted to determine the effects of flameholder pressure drop on the emissions and performance of lean premixed-prevaporized combustors. A conical flameholder mounted in a diverging duct was tested with two values of flameholder blockage. Emissions of nitrogen oxides, carbon monoxide, carbon dioxide, and unburned hydrocarbons were measured for combustor entrance conditions of 600 to 800 K air temperature, 0.3 MPa to 0.5 MPa pressure, and 20 m/sec to 35 m/sec reference velocity. Jet A fuel was injected at flow rates corresponding to an equivalence ratio range from 0.8 down to the lean stability limit. Emission results for the high-blockage flameholder were a substantial improvement over the low-blockage emission results. A correlation of combustion efficiency with flameholder pressure drop was developed for pressure drops less than 9 percent

Quantum Hall effect in narrow graphene ribbons

The edge states in the integer quantum Hall effect are known to be significantly affected by electrostatic interactions leading to the formation of compressible and incompressible strips at the boundaries of Hall bars. We show here, in a combined experimental and theoretical analysis, that this does not hold for the quantum Hall effect in narrow graphene ribbons. In our graphene Hall bar, which is only 60 nm wide, we observe the quantum Hall effect up to Landau level index k=2 and show within a zero free-parameter model that the spatial extent of the compressible and incompressible strips is of a similar magnitude as the magnetic length. We conclude that in narrow graphene ribbons the single-particle picture is a more appropriate description of the quantum Hall effect and that electrostatic effects are of minor importance.Comment: RevTex, 5 pages, 4 figures (matches published version

Methodological Reflections on the MOND/Dark Matter Debate

The paper re-examines the principal methodological questions, arising in the debate over the cosmological standard model's postulate of Dark Matter vs. rivalling proposals that modify standard (Newtonian and general-relativistic) gravitational theory, the so-called Modified Newtonian Dynamics (MOND) and its subsequent extensions. What to make of such seemingly radical challenges of cosmological orthodoxy? In the first part of our paper, we assess MONDian theories through the lens of key ideas of major 20th century philosophers of science (Popper, Kuhn, Lakatos, and Laudan), thereby rectifying widespread misconceptions and misapplications of these ideas common in the pertinent MOND-related literature. None of these classical methodological frameworks, which render precise and systematise the more intuitive judgements prevalent in the scientific community, yields a favourable verdict on MOND and its successors -- contrary to claims in the MOND-related literature by some of these theories' advocates; the respective theory appraisals are largely damning. Drawing on these insights, the paper's second part zooms in on the most common complaint about MONDian theories, their ad-hocness. We demonstrate how the recent coherentist model of ad-hocness captures, and fleshes out, the underlying -- but too often insufficiently articulated -- hunches underlying this critique. MONDian theories indeed come out as severely ad hoc: they do not cohere well with either theoretical or empirical-factual background knowledge. In fact, as our complementary comparison with the cosmological standard model's Dark Matter postulate shows, with respect to ad-hocness, MONDian theories fare worse than the cosmological standard model.Comment: forthcoming in Studies in History and Philosophy of Scienc

The Virtues of Pursuit-Worthy Speculation: The Promises of Cosmic Inflation

The paper investigates the historical and contemporary pursuit-worthiness of cosmic inflation-the rationale for working on it (rather than necessarily the evidential support for claims to its approximate truth): what reasons existed, and exist, that warrant inflation's status as the mainstream paradigm studied, explored, and further developed by the majority of the cosmology community? We'll show that inflation exemplifies various salient theory virtues: explanatory depth, unifying/integrative power, fertility and positive heuristics, the promotion of understanding, and the prospect (and passing) of novel benchmark tests. This, we'll argue, constitutes inflation's auspicious promise. It marks inflation as preferable over both the inflation-less Hot Big Bang Model, as well as rivals to inflation: inflation, we maintain, rightly deserved, and continues to deserve, the concerted research efforts it has enjoyed.Comment: Forthcoming in British Journal for the Philosophy of Scienc

Early CRT monitoring using time-domain optical coherence tomography does not add to visual acuity for predicting visual loss in patients with central retinal vein occlusion treated with intravitreal ranibizumab:A secondary analysis of trial data

Our primary purpose was to assess the clinical (predictive) validity of central retinal thickness (CRT) and best corrected visual acuity (BCVA) at 1 week and 1 month after starting treatment with ranibizumab for central retinal vein occlusion. The authors also assessed detectability of response to treatment

Bringing Salary Transparency to the World: Computing Robust Compensation Insights via LinkedIn Salary

The recently launched LinkedIn Salary product has been designed with the goal of providing compensation insights to the world's professionals and thereby helping them optimize their earning potential. We describe the overall design and architecture of the statistical modeling system underlying this product. We focus on the unique data mining challenges while designing and implementing the system, and describe the modeling components such as Bayesian hierarchical smoothing that help to compute and present robust compensation insights to users. We report on extensive evaluation with nearly one year of de-identified compensation data collected from over one million LinkedIn users, thereby demonstrating the efficacy of the statistical models. We also highlight the lessons learned through the deployment of our system at LinkedIn.Comment: Conference information: ACM International Conference on Information and Knowledge Management (CIKM 2017

An investigation of stopover ecology of the red knot on the Virginia Barrier Island

The Virginia barrier island chain plays a significant role in the life cycle of many of the most vulnerable shorebird species in North America. The large areas of relatively undisturbed beach and marsh habitat available to shorebirds during the migrator

DNA tumor virus oncoproteins and retinoblastoma gene mutations share the ability to relieve the cells requirement for cyclin D1 function in G1

The retinoblastoma gene product (pRB) participates in the regulation of the cell division cycle through complex formation with numerous cellular regulatory proteins including the potentially oncogenic cyclin D1. Extending the current view of the emerging functional interplay between pRB and D-type cyclins, we now report that cyclin D1 expression is positively regulated by pRB. Cyclin D1 mRNA and protein is specifically downregulated in cells expressing SV40 large T antigen, adenovirus E1A, and papillomavirus E7/E6 oncogene products and this effect requires intact RB-binding, CR2 domain of E1A. Exceptionally low expression of cyclin D1 is also seen in genetically RB-deficient cell lines, in which ectopically expressed wild-type pRB results in specific induction of this G1 cyclin. At the functional level, antibody-mediated cyclin D1 knockout experiments demonstrate that the cyclin D1 protein, normally required for G1 progression, is dispensable for passage through the cell cycle in cell lines whose pRB is inactivated through complex formation with T antigen, E1A, or E7 oncoproteins as well as in cells which have suffered loss-of-function mutations of the RB gene. The requirement for cyclin D1 function is not regained upon experimental elevation of cyclin D1 expression in cells with mutant RB, while reintroduction of wild-type RB into RB-deficient cells leads to restoration of the cyclin D1 checkpoint. These results strongly suggest that pRB serves as a major target of cyclin D1 whose cell cycle regulatory function becomes dispensable in cells lacking functional RB. Based on available data including this study, we propose a model for an autoregulatory feedback loop mechanism that regulates both the expression of the cyclin D1 gene and the activity of pRB, thereby contributing to a G1 phase checkpoint control in cycling mammalian cells

A relativistically covariant version of Bohm's quantum field theory for the scalar field

We give a relativistically covariant, wave-functional formulation of Bohm's quantum field theory for the scalar field based on a general foliation of space-time by space-like hypersurfaces. The wave functional, which guides the evolution of the field, is space-time-foliation independent but the field itself is not. Hence, in order to have a theory in which the field may be considered a beable, some extra rule must be given to determine the foliation. We suggest one such rule based on the eigen vectors of the energy-momentum tensor of the field itself.Comment: 1 figure. Submitted to J Phys A. 20/05/04 replacement has additional references and a few minor changes made for clarity. Accepted by J Phys