12 research outputs found
THE FINANCIAL CRISIS AND THE EMERGING MARKETS
The emerging markets emerge and develop in the larger context of the international financial market
development "is a consequence of the needs expressed by investors and those who wish to place their financial capital."
Thus, to achieve a certain level of saturation economic zones and the lack of attractiveness of gains obtainable in
certain markets determine the migration of capital to areas that are or may become interesting in terms of the gains
that are achieved by investing in these areas in conjunction minimizing market risk assumed
Self-organised criticality in base-pair breathing in DNA with a defect
We analyse base-pair breathing in a DNA sequence of 12 base-pairs with a
defective base at its centre. We use both all-atom molecular dynamics (MD)
simulations and a system of stochastic differential equations (SDE). In both
cases, Fourier analysis of the trajectories reveals self-organised critical
behaviour in the breathing of base-pairs. The Fourier Transforms (FT) of the
interbase distances show power-law behaviour with gradients close to -1. The
scale-invariant behaviour we have found provides evidence for the view that
base-pair breathing corresponds to the nucleation stage of large-scale DNA
opening (or 'melting') and that this process is a (second-order) phase
transition. Although the random forces in our SDE system were introduced as
white noise, FTs of the displacements exhibit pink noise, as do the
displacements in the AMBER/MD simulations.Comment: 18 pages, 8 figure
Stochastic nonlinear models of DNA breathing at a defect
Deoxyribonucleic acid (DNA) is a long polymer consisting of two chains of bases, in which the genetic information is stored. A base from one chain has a corresponding base on the other chain which together form a so-called base-pair. Molecular-dynamics simulations of a normal DNA duplex show that breathing events – the temporary opening of one or more base-pairs – typically occur on the microsecond time-scale. Using the molecular dynamics package AMBER, we analyse, for different twist angles in the range 30-40 degrees of twist, a 12 basepair DNA duplex solvated in a water box, which contains the ’rogue’ base difluorotoluene (F) in place of a thymine base (T). This replacement makes breathing occur on the nanosecond time-scale. The time spent simulating such large systems, as well as the variation of breathing length and frequency with helical twist, determined us to create a simplified model, which is capable to predict with accuracy the DNA behaviour.
Starting from a nonlinear Klein-Gordon lattice model and adding noise and damping to our system, we obtain a new mesoscopic model of the DNA duplex, close to that observed in experiments and all-atom MD simulations. Defects are considered in the inter-chain interactions as well as in the along-chain interactions. The system parameters are fitted to AMBER data using the maximum likelihood method. This model enables us to discuss the role of the fluctuation-dissipation relations in the derivation of reduced (mesoscopic) models, the differences between the potential of mean force and the potential energies used in Klein-Gordon lattices and how breathing can be viewed as competition between the along-chain elastic energy, the inter-chain binding energy and the entropy term of the system’s free energy.
Using traditional analysis methods, such as principal component analysis, data autocorrelation, normal modes and Fourier transform, we compare the AMBER and SDE simulations to emphasize the strength of the proposed model. In addition, the Fourier transform of the trajectory of the A-F base-pair suggests that DNA is a self-organised system and our SDE model is also capable of preserving this behaviour. However, we reach the conclusion that the critical DNA behaviour needs further investigations, since it might offer some information about bubble nucleation and growth and even about DNA transcription and replication
THE CHART ROMANIA-NATO-UE
viewed in the context of
geopolitical and geostrategic current and through
the elements of distinction in terms of identity and
cultural institutions, chart Romania - NATO / Israel
- EU stands under the sign of the common interest
channel, firstly, on common values and hence the
collective interests of the partners involved in the
two organizational structures. Noteworthy in this
context is the extent of bilateral involvement of
Romania in the bodies and the politico-military,
represented by NATO (the North Atlantic Treaty
Organization), which is primarily military values
and the construction superstate permanent
expansion and development - European Union ,
both generating as much for our country as
obligations of a politico-military security, and
economic, social, institutional, cultural
THE ACTIONS PROGRAMMES IN THE FIELD OF ENVIRONMENT AND THE INTEGRATED PRODUCT POLICY
One of the most important strategies to achieve the objectives of sustainable development is to promote a
coherent legal system in the European Union. The trends and priorities are mapped and monitored under the
Programme of Action on the environment.
The environmental Action Programmes are documents underpinning EU environmental policy. The first of
these programs was adopted by the European Council in 1972 and was followed by five others. These action
programs are actually a combination of medium-term programs, coupled with a strategic approach and is
characterized by a vertical and sectoral environmental problems. Since 1973, the European Community action
program in the field of environment have become an increasingly important role.
The European Community Treaty of 1986 is the legal basis of EU environmental policy.
The Article 174 outlines environmental policy objectives and defines its purpose - ensuring a high level of
environmental protection taking into account the diversity of situations in different regions of the European Union.
The underlying objectives of EU environmental policy, under Article 174, are:
• the preserve, protect and improve the environment;
• the protection of human health;
•the rational use of natural resources;
•a promoting measures at international level to treat regional environmental issues.
The Article 175 identifies the appropriate legislative procedures to this end and establishes the decisionmaking
in environmental policy.
The Article 176 allows Member States to adopt and stricter standards if it is deemed important and if it is
justified.
The "Sustainable development" is mentioned early in Art. 2 of the Treaty of Amsterdam Treaty which
underlies the formation of the European Community.
The Article 6 promotes sustainable development as a cross-cutting policy of the European Union,
highlighting the need to integrate environmental protection requirements into the definition and implementation of EU
sectorial policies.
The Article 95 of the Treaty of Amsterdam is the harmonization of legislation on health, environment and
consumer protection in the Member States, while allowing the inclusion of national legal provisions in order to better
protect the environment
THE OPPORTUNITY TO ADDRESS THE SUSTAINABLE INDUSTRIAL DEVELOPMENT IN ROMANIA
Its economy experienced a sharp decline, coupled with a process of deindustrialization, projected on a phase
of the property. In these circumstances, to discuss the sustainable development may seem inappropriate; therefore, be
taken in steps such as halting the decline of the economy and industry; the industry revitalization and growth; the
development that takes place according to the criteria of sustainable development.
To this must be stopped declining industrial output and output stabilization. It must be found and made the
necessary conditions leading to full use of the potential of the country, to stimulate those structural changes that allow
the country to fall market economy conditions.
To address the main criteria for sustainable industrial development since this time of economic downturn may
be several reasons such as the need to respect the provisions of international treaties to which Romania is a party.
Some of them may be mentioned as: putting control of Earth's greenhouse effect, preventing damage to the ozone layer
(waiving of manufacture and use of chlorofluorocarbons), transboundary pollution and protection of large water
basins of the border. Each of these treaties contain provisions that are converging concept of sustainable development.
The entry into the European Union implies aligning Romanian legislation in the EU
The EU Council adopted a common position, relative to a plan of action intended to give a new political
impetus of the fifth environmental action program. The main objective of this program is the promotion of sustainable
development throughout the economy.
The Action Plan identifies priority areas for action, namely:
• better integration of environmental issues into policies as those of agriculture, transport, energy, industry
and tourism;
• further development of basic tools acting on the market and, in particular, horizontal instruments;
• improving enforcement and implementation of environmental legislation;
• raising awareness to protect the environment.
The following are considered priority themes: control climate change; protecting the ozone layer; acid rain
control, improving air quality; water resource management; waste management; protection against noise; nature
protection and biodiversity.
The privatization of industrial enterprises is also an opportunity to assess damage to these facilities, the
environment and solutions to remedy such damage. Existing law requires, these actions pave the ground for a
sustainable approach to development industry.
The works market organic products or opportunities for are: agricultural and food products labeled organic;
technologies and processes used to "clean" manufacturing; Products with low pollutant potential (low sulfur fuels,
unleaded petrol cars with catalytic emission control, etc.); use of renewable energy and raw materials to form the
corresponding markets
THE COMPARATIVE ANALYSIS OF CARDS ISSUED IN ROMANIA. THE ELECTRONIC PAYMENTS BASED ON THE VISA CARD
The electronic payments are a significant invention of sec. XXI, on the background of the development of
telecommunications information technology in Romania. The spread of computers, public, fast and cheap telecoms,
large-scale networks, and the Internet have created national, regional and global infrastructure, the current electronic
payment systems, electronic money transfers and today's infrastructure of developed and developing economies. The
electronic payment systems are the most dynamic part of the computerized, digital, local, regional and global economy.
The components of the systems are card payment systems, e-commerce, and interbank and inter-company electronic
transfers, with Visa and MasterCard telecommunication networks, the Internet and the SWIFT network
ECONOMICAL CRISIS IN ROMANIA – A CONSEQUENCE OF THE WRONG MIX OF MACRO-ECONOMICAL POLICIES
The economical crisis Romania
starts to cross is mainly an internal crisis determined by
the wrong mix of macro-economical policies established
in the last years. Economic growth proves to be
unhealthy; that is because we have had a growth based
on consumption financed on debt during these years.
Private consumption was excessive, but the population
should not be blamed: all the macro-economical
measures have been pro-cyclic, stimulating
consumption; and the most damaging of the all, the
unique rate, is still protected by its initiators who do not
want to admit they were wrong. The unique rate has
stimulated the consumption and we have nowadays the
first crisis of overconsumption in Romania. The main
cause is the excessive consumption on debt. The
population cannot be blamed, but in the future it can be
better informed and surely more precautious regarding
the expectations for the own incomes. In exchange, the
government may be criticized because it made a
monumental strategic mistake: in a time of economical
increase, it consumed all this increase and it indebted
itself additionally. The budgetary deficit increased from
1,3% of PIB in 2008 to 2,6% last year and probably
over 3% this year. Since the government has got to
borrow hundreds of million euro with the date of
payment of one week, the only logical conclusion is that
there are no money for the current expenditures or for
the ones already budgeted on the current year. It is
absolutely inacceptable in a time of high economical
increase for the budgetary deficit to increase, in
consequence, the costs regarding its financing on a short
term
THE ROMANIAN ENERGY STRATEGY FOR 2014-2020
In a context of increasingly globalized Romania's energy policy is implemented through changes and
developments taking place at national and European level. In this context, Romania's energy policy should be correlated
with similar documents at the European level so as to ensure our country's policy of European Union policy in the field.
"National Energy Strategy for 2014-2020" represents significant progress in harmonizing the interests and priorities of EU
policy in the field. Provisions explicit strategy focuses on three core objectives of EU energy policy, namely:
1) Strengthening the security of energy supply in the EU
2) Sustainable development
3) development of competitive markets as the main means of achieving objectives. They went bankrupt, while others have
tried to overcome the crisis through loans or other strategies, such as layoffs, wage reduction or restriction markets. Anticrisis
measures governments have taken individually, to protect the national economy and collectively (at EU level)
THE EXPANSION OF MULTINATIONAL COMPANIES GLOBALLY
The multinational firms now have a very important role to play in all countries' economies and international
economic relations, turning into an increasingly important issue for governments. Through foreign direct investment,
these firms can bring substantial gains to both home and host states by contributing to the efficient use of capital,
technology and human resources across countries, and thus can play an important role in the development of economic
prosperity and social issues.
So the common goal of all countries is to stimulate positive contributions by which multinational firms can
make economic and social progress and reduce or solve the difficulties that may arise from their operations