1-Benzyl-3-[3-(naphthalen-2-yl­oxy)prop­yl]imidazolium hexa­fluoro­phosphate

In the title salt, C23H23N2O+·PF6 −, the PF6 − anion is highly disordered (occupancy ratios of 0.35:0.35:0.3, 0.7:0.15:0.15, 0.7:0.3 and 0.35:0.35:0.15:0.15) with the four F atoms in the equatorial plane rotating about the axial F—P—F bond. The mean plane of the imidazole ring makes dihedral angles of 82.44 (17) and 14.39 (16)°, respectively, with the mean planes of the benzene ring and the naphthalene ring system. The crystal structure is stabilized by C—H⋯F hydrogen bonds. In addition, π–π [centroid–centroid distances = 3.7271 (19)–3.8895 (17) Å] and C—H⋯π inter­actions are observed

When 3D Bounding-Box Meets SAM: Point Cloud Instance Segmentation with Weak-and-Noisy Supervision

Learning from bounding-boxes annotations has shown great potential in weakly-supervised 3D point cloud instance segmentation. However, we observed that existing methods would suffer severe performance degradation with perturbed bounding box annotations. To tackle this issue, we propose a complementary image prompt-induced weakly-supervised point cloud instance segmentation (CIP-WPIS) method. CIP-WPIS leverages pretrained knowledge embedded in the 2D foundation model SAM and 3D geometric prior to achieve accurate point-wise instance labels from the bounding box annotations. Specifically, CP-WPIS first selects image views in which 3D candidate points of an instance are fully visible. Then, we generate complementary background and foreground prompts from projections to obtain SAM 2D instance mask predictions. According to these, we assign the confidence values to points indicating the likelihood of points belonging to the instance. Furthermore, we utilize 3D geometric homogeneity provided by superpoints to decide the final instance label assignments. In this fashion, we achieve high-quality 3D point-wise instance labels. Extensive experiments on both Scannet-v2 and S3DIS benchmarks demonstrate that our method is robust against noisy 3D bounding-box annotations and achieves state-of-the-art performance

Economic Burden for Lung Cancer Survivors in Urban China.

BackgroundWith the rapid increase in the incidence and mortality of lung cancer, a growing number of lung cancer patients and their families are faced with a tremendous economic burden because of the high cost of treatment in China. This study was conducted to estimate the economic burden and patient responsibility of lung cancer patients and the impact of this burden on family income.MethodsThis study uses data from a retrospective questionnaire survey conducted in 10 communities in urban China and includes 195 surviving lung cancer patients diagnosed over the previous five years. The calculation of direct economic burden included both direct medical and direct nonmedical costs. Indirect costs were calculated using the human capital approach, which measures the productivity lost for both patients and family caregivers. The price index was applied for the cost calculation.ResultsThe average economic burden from lung cancer was $43,336 per patient, of which the direct cost per capita was$42,540 (98.16%) and the indirect cost per capita was $795 (1.84$30,277 per capita, which accounted for 171% of the household annual income, a percentage that fell to 107% after subtracting the compensation from medical insurance.ConclusionsThe economic burden for lung cancer patients is substantial in the urban areas of China, and an effective control strategy to lower the cost is urgently needed

Robust Outdoor Vehicle Visual Tracking Based on k-Sparse Stacked Denoising Auto-Encoder

Robust visual tracking for outdoor vehicle is still a challenging problem due to large object appearance variations caused by illumination variation, occlusion, and fast motion. In this chapter, k-sparse constraint is added to the encoder part of stacked auto-encoder network to learn more invariant feature of object appearance, and a stacked k-sparse-auto-encoder–based robust outdoor vehicle tracking method under particle filter inference is further proposed to solve the problem of appearance variance during the tracking. Firstly, a stacked denoising auto-encoder is pre-trained to learn the generic feature representation. Then, a k-sparse constraint is added to the stacked denoising auto-encoder, and the encoder of k-sparse stacked denoising auto-encoder is connected with a classification layer to construct a classification neural network. Finally, confidence of each particle is computed by the classification neural network and is used for online tracking under particle filter framework. Comprehensive tracking experiments are conducted on a challenging single-object tracking benchmark. Experimental results show that our tracker outperforms most state-of-the-art trackers

Palatine tonsillar metastasis of lung adenocarcinoma: An unusual immunohistochemical phenotype and a potential diagnostic pitfall

Metastasis rarely occurs to the palatine tonsils. Herein, we present an exceedingly rare case of palatine tonsillar metastasis from poorly differentiated lung adenocarcinoma with anaplastic lymphoma kinase (ALK) mutation in a 51-year-old woman. The patient manifested clinically as pharyngalgia without obvious respiratory symptoms, with swelling tonsil histomorphologically resembling lymphoma and partially expressing the markers of epithelial and squamous cell carcinoma (CK5/6, P63, and P40). Due to the non-specific immunohistochemical expression, it is easily misdiagnosed as a primary poorly differentiated squamous cell carcinoma of the tonsil. This case highlights the importance of a comprehensive assessment of suspicious tonsillar lesions, that may be a sign of a primary malignancy elsewhere in the body

(2′-Amino-4,4′-bi-1,3-thia­zol-2-aminium-κ2 N,N′)aqua­[citrato(4−)-κ3 O,O′,O′′)chromium(III) dihydrate

In the title compound, [Cr(C6H7N4S2)(C6H4O7)(H2O)]·2H2O, the CrIII atom is in a distorted octa­hedral environment, coordinated by one water mol­ecule, two N atoms from a protonated diamino­bithia­zole ligand and three O atoms from a citrate(4−) anion. The complex is zwitterionic, with the H atom from the uncoordinated carboxyl­ate group of the citrate anion transferred to one amino group of the diamino­bithia­zole ligand. O—H⋯O and N—H⋯O hydrogen bonds link the complexes into layers including the two uncoordinated water mol­ecules