384 research outputs found
Synergistic therapeutic effect of arsenic trioxide and radiotherapy in BALB/C nude mice bearing nasopharyngeal carcinoma xenografts
It has been shown that arsenic trioxide (ATO) induced apoptosis in human nasopharyngeal carcinoma cells and inhibited the growth of nasopharyngeal carcinoma xenografts (NPCX) in nude mice. Aim: The present study was designed to determine whether ATO at the non-toxic dose level could potentiate the therapeutic effectiveness of radiation therapy in nasopharyngeal carcinoma, using a BALB/C nude mouse xenograft model. Methods: The mice bearing NPCX were treated with radiation alone (2, 4, and 6 Gy), ATO alone (4 mg/kg/day x 6 days), and ATO plus radiation at the same dosage levels. Time of tumor growth delay (defined as the time necessary for the tumor to grow four-fold of its initial volume after, compared with untreated tumors) and toxic effects were determined. Results: The low dose ATO alone has no pronounced effects on tumor growth delay compared to untreated control. However, compared with radiation alone, the combined regimen delayed the tumor growth by 2β10 days and had no significant toxic effects such as the liver function damage. Conclusions: Combination of ATO at non-toxic dose level and radiation has synergistic effects on tumor growth inhibition in vivo and is well tolerated.Π£ΡΡΠ°Π½ΠΎΠ²Π»Π΅Π½ΠΎ, ΡΡΠΎ ΡΡΠΈΠΎΠΊΡΠΈΠ΄ ΠΌΡΡΡΡΠΊΠ° (Π’ΠΠ) ΠΈΠ½Π΄ΡΡΠΈΡΡΠ΅Ρ Π°ΠΏΠΎΠΏΡΠΎΠ· Π² ΠΊΠ»Π΅ΡΠΊΠ°Ρ
ΠΊΠ°ΡΡΠΈΠ½ΠΎΠΌΡ Π½ΠΎΡΠΎΠ³Π»ΠΎΡΠΊΠΈ ΡΠ΅Π»ΠΎΠ²Π΅ΠΊΠ° ΠΈ ΠΈΠ½Π³ΠΈΠ±ΠΈΡΡΠ΅Ρ
ΡΠΎΡΡ ΠΊΡΠ΅Π½ΠΎΠ³ΡΠ°ΡΡΠ° ΠΊΠ°ΡΡΠΈΠ½ΠΎΠΌΡ Π½ΠΎΡΠΎΠ³Π»ΠΎΡΠΊΠΈ Ρ Π°ΡΠΈΠΌΠΈΡΠ΅ΡΠΊΠΈΡ
ΠΌΡΡΠ΅ΠΉ. Π¦Π΅Π»Ρ ΡΠ°Π±ΠΎΡΡ β ΡΡΡΠ°Π½ΠΎΠ²ΠΈΡΡ ΡΠ΅ΡΠ°ΠΏΠ΅Π²ΡΠΈΡΠ΅ΡΠΊΡΡ ΡΡΡΠ΅ΠΊΡΠΈΠ²Π½ΠΎΡΡΡ
ΡΠ°Π΄ΠΈΠΎΡΠ΅ΡΠ°ΠΏΠΈΠΈ Π² ΠΊΠΎΠΌΠ±ΠΈΠ½Π°ΡΠΈΠΈ Π’ΠΠ Π² Π½Π΅ΡΠΎΠΊΡΠΈΡΠ½ΠΎΠΉ Π΄ΠΎΠ·Π΅ ΠΌΡΡΠ°ΠΌ Π»ΠΈΠ½ΠΈΠΈ BALB/ Ρ ΠΊΡΠ΅Π½ΠΎΠ³ΡΠ°ΡΡΠΎΠΌ ΠΊΠ°ΡΡΠΈΠ½ΠΎΠΌΡ Π½ΠΎΡΠΎΠ³Π»ΠΎΡΠΊΠΈ.
ΠΠ΅ΡΠΎΠ΄Ρ: ΠΆΠΈΠ²ΠΎΡΠ½ΡΠ΅ Ρ ΠΊΡΠ΅Π½ΠΎΠ³ΡΠ°ΡΡΠΎΠΌ ΠΊΠ°ΡΡΠΈΠ½ΠΎΠΌΡ Π½ΠΎΡΠΎΠ³Π»ΠΎΡΠΊΠΈ ΠΏΠΎΠ»ΡΡΠ°Π»ΠΈ Π»ΠΈΠ±ΠΎ ΡΠΎΠ»ΡΠΊΠΎ ΡΠ°Π΄ΠΈΠΎΡΠ΅ΡΠ°ΠΏΠΈΡ (2, 4 ΠΈ 6 ΠΡ) ΠΈΠ»ΠΈ Π’ΠΠ
(4 ΠΌΠ³/ΠΊΠ³/Π΄Π΅Π½Ρ Π² ΡΠ΅ΡΠ΅Π½ΠΈΠ΅ 6 Π΄Π½Π΅ΠΉ), ΠΈΠ»ΠΈ ΠΈΡ
ΠΊΠΎΠΌΠ±ΠΈΠ½Π°ΡΠΈΡ Π² ΡΠ΅Ρ
ΠΆΠ΅ ΡΠ΅ΠΆΠΈΠΌΠ°Ρ
ΠΈ Π΄ΠΎΠ·Π°Ρ
. ΠΠ°Π΄Π΅ΡΠΆΠΊΡ ΡΠΎΡΡΠ° ΠΎΠΏΡΡ
ΠΎΠ»ΠΈ ΠΎΠΏΡΠ΅Π΄Π΅Π»ΡΠ»ΠΈ ΠΊΠ°ΠΊ
ΡΠ°Π·Π»ΠΈΡΠΈΠ΅ Π²ΠΎ Π²ΡΠ΅ΠΌΠ΅Π½ΠΈ, Π½Π΅ΠΎΠ±Ρ
ΠΎΠ΄ΠΈΠΌΠΎΠΌ Π΄Π»Ρ Π΄ΠΎΡΡΠΈΠΆΠ΅Π½ΠΈΡ ΠΎΠΏΡΡ
ΠΎΠ»ΡΡ 4-ΠΊΡΠ°ΡΠ½ΠΎΠ³ΠΎ ΠΎΠ±ΡΠ΅ΠΌΠ° ΠΏΠΎ ΡΡΠ°Π²Π½Π΅Π½ΠΈΡ Ρ Π½Π°ΡΠ°Π»ΡΠ½ΡΠΌ ΠΎΠ±ΡΠ΅ΠΌΠΎΠΌ Π²
ΠΎΠΏΡΡΠ½ΠΎΠΉ Π³ΡΡΠΏΠΏΠ΅ versus ΡΠ°ΠΊΠΎΠ²ΠΎΠ³ΠΎ Π² ΠΊΠΎΠ½ΡΡΠΎΠ»ΡΠ½ΠΎΠΉ Π³ΡΡΠΏΠΏΠ΅. Π Π΅Π·ΡΠ»ΡΡΠ°ΡΡ: Π²Π²Π΅Π΄Π΅Π½ΠΈΠ΅ Π’ΠΠ Π² Π½ΠΈΠ·ΠΊΠΎΠΉ Π΄ΠΎΠ·Π΅ Π½Π΅ ΠΎΠΊΠ°Π·ΡΠ²Π°Π»ΠΎ Π²ΡΡΠ°ΠΆΠ΅Π½Π½ΠΎΠ³ΠΎ
Π²Π»ΠΈΡΠ½ΠΈΡ Π½Π° ΡΠΎΡΡ ΠΎΠΏΡΡ
ΠΎΠ»ΠΈ ΠΏΠΎ ΡΡΠ°Π²Π½Π΅Π½ΠΈΡ Ρ ΠΏΠΎΠΊΠ°Π·Π°ΡΠ΅Π»ΡΠΌΠΈ Π² ΠΊΠΎΠ½ΡΒΡΠΎΠ»ΡΠ½ΠΎΠΉ Π³ΡΡΠΏΠΏΠ΅, Π° Π² ΠΊΠΎΠΌΠ±ΠΈΠ½Π°ΡΠΈΠΈ Ρ ΠΎΠ±Π»ΡΡΠ΅Π½ΠΈΠ΅ΠΌ ΠΏΡΠΈΠ²ΠΎΠ΄ΠΈΠ»ΠΎ
ΠΊ Π·Π°Π΄Π΅ΡΠΆΠΊΠ΅ ΡΠΎΡΡΠ° ΠΎΠΏΡΡ
ΠΎΠ»ΠΈ Π½Π° 2β12 ΡΡΡ ΠΏΠΎ ΡΡΠ°Π²Π½Π΅Π½ΠΈΡ Ρ ΠΏΠΎΠΊΠ°Π·Π°ΡΠ΅Π»ΡΠΌΠΈ Ρ ΠΆΠΈΠ²ΠΎΡΠ½ΡΡ
, ΠΏΠΎΠ»ΡΡΠ°Π²ΡΠΈΡ
ΡΠΎΠ»ΡΠΊΠΎ Π»ΡΡΠ΅Π²ΡΡ ΡΠ΅ΡΠ°ΠΏΠΈΡ
ΠΏΡΠΈ ΠΎΡΡΡΡΡΡΠ²ΠΈΠΈ Π²ΡΡΠ°ΠΆΠ΅Π½Π½ΡΡ
ΠΏΠΎΠ±ΠΎΡΠ½ΡΡ
ΡΡΡΠ΅ΠΊΡΠΎΠ². ΠΡΠ²ΠΎΠ΄Ρ: ΠΊΠΎΠΌΠ±ΠΈΠ½Π°ΡΠΈΡ Π’ΠΠ Π² Π½Π΅ΡΠΎΠΊΡΠΈΡΠ΅ΡΠΊΠΎΠΉ Π΄ΠΎΠ·Π΅ ΠΈ Π»ΡΡΠ΅Π²ΠΎΠΉ ΡΠ΅ΡΠ°ΠΏΠΈΠΈ
ΠΏΡΠΈΠ²ΠΎΠ΄ΠΈΡ ΠΊ ΠΈΠ½Π³ΠΈΠ±ΠΈΡΠΎΠ²Π°Π½ΠΈΡ ΡΠΎΡΡΠ° ΠΎΠΏΡΡ
ΠΎΠ»ΠΈ in vivo ΠΈ Π½Π΅ Π²ΡΠ·ΡΠ²Π°Π΅Ρ ΠΏΠΎΠ±ΠΎΡΠ½ΡΡ
ΡΡΡΠ΅ΠΊΡΠΎΠ².
ΠΠ»ΡΡΠ΅Π²ΡΠ΅ ΡΠ»ΠΎΠ²Π°: ΡΡΠΈΠΎΠΊΡΠΈΠ΄ ΠΌΡΡΡΡΠΊΠ°, ΡΠ°Π΄ΠΈΠΎΡΠ΅ΡΠ°ΠΏΠΈΡ, ΠΊΡΠ΅Π½ΠΎΠ³ΡΠ°ΡΡ ΠΊΠ°ΡΡΠΈΠ½ΠΎΠΌΡ Π½ΠΎΡΠΎΠ³Π»ΠΎΡΠΊΠΈ
Correlation between chemical composition, EHGE and TME of corn for ducks
Correlations between chemical composition, enzymatic hydrolysate gross energy (EHGE), and true metabolizable energy (TME) of corn for ducks were investigated. Twenty-two corn samples were collected from various regions in 11 provinces of China. The crude protein (CP), ether extract (EE), neutral detergent fibre (NDF), Ash, gross energy (GE), dry matter (DM), amylopectin (AP), amylose (AM), total starch (TS), and AP/AM were determined for each sample. Five of the samples of corn were chosen at the mean, mean Β± 1 standard deviation (SD), and mean Β± 2 SD based on AP/AM. The EHGE of these samples was analysed using the pepsin-artificial small intestinal fluid enzymatic method. These five samples were also force-fed to male Cherry Valley ducks to assay their TME. Finally, correlation analyses were performed, and regression equations were established. Ash content, GE, and TS were highly related to EHGE. Univariate prediction equations were EHGE = 11.8566Ash-0.0421 (P <0.05), EHGE = 0.1535GE1.5642 (P <0.05), and EHGE = 0.1020TS1.1561 (P <0.05). The total starch, AP/AM, and ash of the chemical compositions were highly related to TME. The corresponding univariate regression equations were TME = 21.9355TS-0.0910 (P <0.05), TME = 15.6590AP/AM-0.0559 (P <0.05), and TME = 15.0778Ash0.0442 (P <0.05). The mean EHGE was equivalent to 78.5% of TME, but their correlation coefficient was low. In conclusion, chemical composition was predictive of EHGE and TME of corn samples for ducks, but the correlation of EHGE and TME was low
Keywords: Cherry Valley duck, amylopectin, amylose, true metabolizable energ
The Y(4260) as an omega chi_{c1} molecular state
It is suggested that the newly observed Y(4260) by BARBAR collaboration is a
molecular state composed of an omega and a chi_{c1}. Both the production and
decay properties are discussed. A consequence for this molecular state,
Y(4260), is that it decays into pi+pi-pi0 chi_{c1} with similar rate to pi+ pi-
J/psi. It is also expected that Y(4260) -> pi0 pi0 J/psi is produced at half
rate as Y(4260) ->pi+ pi- J/psi. These decay modes should be searched for in
the B factories using initial state radiative return data and B decay data as
well.Comment: 5 pages, 5 figure
Semileptonic decays and Charmonium distribution amplitude
In this paper we study the semileptonic decays of the meson in the
Light-Cone Sum Rule (LCSR) approach. The result for each channel depends on the
corresponding distribution amplitude of the final meson. For the case of
decaying into a pseudoscalar meson, to twist-3 accuracy only the leading twist
distribution amplitude (DA) is involved if we start from a chiral current. If
we choose a suitable chiral current in the vector meson case, the main twist-3
contributions are also eliminated and we can consider the leading twist
contribution only. The leading twist distribution amplitudes of the charmonium
and other heavy mesons are given by a model approach in the reasonable way.
Employing this charmonium distribution amplitude we find the cross section
which is consistent with Belle
and BaBar's data. Based on this model, we calculate the form factors for
various decay modes in the corresponding regions. Extrapolating the form
factors to the whole kinetic regions, we get the decay widths and branching
ratios for various decay modes including their modes when they are
kinematically accessible.Comment: Changed content partially, Added references, 16 pages,2 figure
New mechanism to cross the phantom divide
Recently, type Ia supernovae data appear to support a dark energy whose
equation of state crosses -1, which is a much more amazing problem than the
acceleration of the universe. We show that it is possible for the equation of
state to cross the phantom divide by a scalar field in the gravity with an
additional inverse power-law term of Ricci scalar in the Lagrangian. The
necessary and sufficient condition for a universe in which the dark energy can
cross the phantom divide is obtained. Some analytical solutions with or
are obtained. A minimal coupled scalar with different potentials,
including quadratic, cubic, quantic, exponential and logarithmic potentials are
investigated via numerical methods, respectively. All these potentials lead to
the crossing behavior. We show that it is a robust result which is hardly
dependent on the concrete form of the potential of the scalar.Comment: 11 pages, 5 figs, v3: several references added, to match the
published versio
Partial Wave Analysis of
BES data on are presented. The
contribution peaks strongly near threshold. It is fitted with a
broad resonance with mass MeV, width MeV. A broad resonance peaking at 2020 MeV is also required
with width MeV. There is further evidence for a component
peaking at 2.55 GeV. The non- contribution is close to phase
space; it peaks at 2.6 GeV and is very different from .Comment: 15 pages, 6 figures, 1 table, Submitted to PL
Direct Measurements of the Branching Fractions for and and Determinations of the Form Factors and
The absolute branching fractions for the decays and
are determined using singly
tagged sample from the data collected around 3.773 GeV with the
BES-II detector at the BEPC. In the system recoiling against the singly tagged
meson, events for and events for decays are observed. Those yield
the absolute branching fractions to be and . The
vector form factors are determined to be
and . The ratio of the two form
factors is measured to be .Comment: 6 pages, 5 figure
Measurements of J/psi Decays into 2(pi+pi-)eta and 3(pi+pi-)eta
Based on a sample of 5.8X 10^7 J/psi events taken with the BESII detector,
the branching fractions of J/psi--> 2(pi+pi-)eta and J/psi-->3(pi+pi-)eta are
measured for the first time to be (2.26+-0.08+-0.27)X10^{-3} and
(7.24+-0.96+-1.11)X10^{-4}, respectively.Comment: 11 pages, 6 figure
Study of J/psi decays to Lambda Lambdabar and Sigma0 Sigma0bar
The branching ratios and Angular distributions for J/psi decays to Lambda
Lambdabar and Sigma0 Sigma0bar are measured using BESII 58 million J/psi.Comment: 11 pages, 5 figure
Measurements of the observed cross sections for exclusive light hadrons containing at , 3.650 and 3.6648 GeV
By analyzing the data sets of 17.3, 6.5 and 1.0 pb taken,
respectively, at , 3.650 and 3.6648 GeV with the BES-II
detector at the BEPC collider, we measure the observed cross sections for
, , ,
and at the three energy
points. Based on these cross sections we set the upper limits on the observed
cross sections and the branching fractions for decay into these
final states at 90% C.L..Comment: 7 pages, 2 figure
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