On Cotorsion pairs of chain complexes

In the paper we first construct a new cotorsion pair, in the category of chain complexes, from two given cotorsion pairs in the category of modules, and then we consider completeness of such pairs under certain conditions.Comment: 11 pages. arXiv admin note: text overlap with arXiv:1210.0196 by other author

Cloning, expression and characterization of novel helicobacter pylori differentiating antigen - Heat shock protein 20

Ph.DDOCTOR OF PHILOSOPH

Trends in incidence of hypertension in Chinese adults, 1991–2009: The China Health and Nutrition Survey

Previous studies have shown an upward trend in the prevalence of hypertension, but data on trend of incidence of hypertension are lacking. We seek to investigate the trends in incidence of hypertension and control of incident hypertension among Chinese adults during 1991–1997 and 2004–2009

A Simulation of the Flight Characteristics of the Deployable Hindwings of Beetle

An insect is an excellent biological object for the bio-inspirations to design and develop a MAV. This paper presents the simulation study of the flight characteristics of the deployable hindwings of beetle, Dorcustitanus platymelus. A 3D geometric model of the beetle was obtained using a 3D laser scanning technique. By studying its hindwings and flight mechanism, the mathematical model of the flapping motion of its hindwings was analyzed. Then a simulation analysis was carried out to analyze and evaluate the flapping flying aerodynamic characteristics. After that, the flow of blood in the hindwing veins was studied through simulation to determine the maximum pressure on a vein surface and the minimum blood flow in flight. A number of interesting bio-inspirations were obtained. It is believed that these findings can be used for the design and development of a MAV with similar flying capabilities to a natural beetle

Molecular characterization of CHST11 and its potential role in nacre formation in pearl oyster Pinctada fucata martensii

Background: C4ST-1 catalyzes the transfer of sulfate groups in the sulfonation of chondroitin during chondroitin sulfate synthesis. Chondroitin sulfate consists of numerous copies of negatively charged sulfonic acid groups that participate in the nucleation process of biomineralization. In the present study, we obtained two CHST11 genes (PmCHST11a and PmCHST11b) which encoded the C4ST-1 and explored the functions of these genes in the synthesis of chondroitin sulfate and in the formation of the nacreous layer of shells. Results: Both PmCHST11a and PmCHST11b had a sulfotransferase-2 domain, a signal peptide and a transmembrane domain. These properties indicated that these genes localize in the Golgi apparatus. Real-time PCR revealed that both PmCHST11a and PmCHST11b were highly expressed in the central zone of the mantle tissue. Inhibiting PmCHST11a and PmCHST11b via RNA interference significantly decreased the expression levels of these genes in the central zone of the mantle tissue and the concentration of chondroitin sulfate in extrapallial fluid. Moreover, shell nacre crystallized irregularly with a rough surface after RNA interference. Conclusions: This study indicated thatPmCHST11a and PmCHST11b are involved in the nacre formation of Pinctada fucata martensii through participating in the synthesis of chondroitin sulfate

Formate Dehydrogenase Improves the Resistance to Formic Acid and Acetic Acid Simultaneously in Saccharomyces cerevisiae

Bioethanol from lignocellulosic biomass is a promising and sustainable strategy to meet the energy demand and to be carbon neutral. Nevertheless, the damage of lignocellulose-derived inhibitors to microorganisms is still the main bottleneck. Developing robust strains is critical for lignocellulosic ethanol production. An evolved strain with a stronger tolerance to formate and acetate was obtained after adaptive laboratory evolution (ALE) in the formate. Transcriptional analysis was conducted to reveal the possible resistance mechanisms to weak acids, and fdh coding for formate dehydrogenase was selected as the target to verify whether it was related to resistance enhancement in Saccharomyces cerevisiae F3. Engineered S. cerevisiae FA with fdh overexpression exhibited boosted tolerance to both formate and acetate, but the resistance mechanism to formate and acetate was different. When formate exists, it breaks down by formate dehydrogenase into carbon dioxide (CO2) to relieve its inhibition. When there was acetate without formate, FDH1 converted CO2 from glucose fermentation to formate and ATP and enhanced cell viability. Together, fdh overexpression alone can improve the tolerance to both formate and acetate with a higher cell viability and ATP, which provides a novel strategy for robustness strain construction to produce lignocellulosic ethanol

Novel Composite Electrolytes of Zr0.92Y0.08O2-α(8YSZ)-Low Melting Point Glass Powder for Intermediate Temperature Solid Oxide Fuel Cells

In this study, Zr0.92Y0.08O2-α(8YSZ) powders were synthesized by the sol-gel method. The chemical physics changes and phase formation temperature of 8YSZ crystal were determined by thermogravimetry analysis and differential scanning calorimetry (TGA-DSC). 8YSZ-low melting point glass powder (8YSZ-glass) composite electrolytes with various weight ratios were prepared and calcined at different temperatures. The X-ray diffraction (XRD) patterns of the composite electrolytes were tested. The effects of synthesis temperature, weight ratio, test temperature, and oxygen partial pressure on the conductivities of 8YSZ-glass composite electrolytes, were also investigated at 400–800 °C. The result of the logσ ~ log(pO2) plot indicates that the 8YSZ-20% glass (700 °C) is almost a pure ionic conductor. The oxygen concentration discharge cell illustrates that the 8YSZ-20% glass (700 °C) composite electrolyte is a good oxygen ion conductor

Genome size and identification of abundant repetitive sequences in Vallisneria spinulosa

Vallisneria spinulosa is a freshwater aquatic plant of ecological and economic importance. However, there is limited cytogenetic and genomics information on Vallisneria. In this study, we measured the nuclear DNA content of Vallisneria spinulosa by flow cytometry, performed a de novo assembly, and annotated repetitive sequences by using a combination of next-generation sequencing (NGS) and bioinformatics tools. The genome size of Vallisneria spinulosa is approximately 3,595 Mbp, in which nearly 60% of the genome consists of repetitive sequences. The majority of the repetitive sequences are LTR-retrotransposons comprising 43% of the genome. Although the amount of sequencing data used in this study was not sufficient for a whole-genome assembly, it could generate an overview of representative elements in the genome. These results will lay a new foundation for further studies on various species that belong to the Vallisneria genus.</p

CD163 and IgG Codefend against Cytotoxic Hemoglobin via Autocrine and Paracrine Mechanisms

JOURNAL OF IMMUNOLOGY190105267-527