Using Evidence in the development of local health policies : Some Evidence from the United Kingdom

Objectives: This paper explores the use of evidence, focusing on economic evidence in particular, in the development of local health policies through an in-depth study of Health Improvement Programmes (HImPs) in England. Methods: A questionnaire was sent to the person responsible for coordinating the development of the HImP in each of the 102 English health authorities. In addition, semi-structured interviews were conducted with 10 HImP leaders, and a random sample of 26 HImP documents was reviewed using a standard pro forma. Results: Of the 102 mail questionnaires sent out, 68 (67%) were returned. It was found that those developing HImPs had multiple objectives, only some of which (e.g., efficiency in healthcare provision) would necessarily require evidence.Where evidence was used, this was a mixture of internal (experiential) and external (empirical) evidence, with the balance (66%) being in favor of the latter. Government reports and guidance from the National Institute for Clinical Excellence (NICE), were the main sources of external evidence, rather than published papers. Key barriers to the use of economic evidence were lack of time and availability and the difficulties in synthesizing information at the local level. Conclusions: Based on responses to our survey, the main ways of increasing the use of evidence in the development of local health policies in England are to produce more evidence-based national guidance and to produce accessible summaries of the available literature for local decision makers

A new dawn? The Roman Catholic Church and environmental issues

This is a PDF version of an article published in New Blackfriars© 1997. The definitive version is available at www.blackwell-synergy.com.This article discusses the stance of the Roman Catholic Church on environmental issues and argues that the Church tends to stay on the fringe rather than get involved. Some of the ways in which Roman Catholic theologians have incorporated environmental issues into theological reflection is discussed, as are environmental challenges facing the Church in Britain (conservation, resources, biodiversity, animal welfare, biotechnology, cooperate/individual ethics, environmental justice, economics/policy development, and global issues)

Einstein-Podolsky-Rosen correlations via dissociation of a molecular Bose-Einstein condensate

Recent experimental measurements of atomic intensity correlations through atom shot noise suggest that atomic quadrature phase correlations may soon be measured with a similar precision. We propose a test of local realism with mesoscopic numbers of massive particles based on such measurements. Using dissociation of a Bose-Einstein condensate of diatomic molecules into bosonic atoms, we demonstrate that strongly entangled atomic beams may be produced which possess Einstein-Podolsky-Rosen (EPR) correlations in field quadratures, in direct analogy to the position and momentum correlations originally considered by EPR.Comment: Final published version (corrections in Ref. [32], updated references

Two-loop supergravity on AdS5×_5\timesS5^5 from CFT

We describe a construction of the two-loop amplitude of four graviton supermultiplets in AdS$_5\times$S$^5$. We start from an ansatz for a preamplitude from which we generate the full amplitude under the action of a specific Casimir operator. The ansatz captures a recent ansatz of Huang and Yuan and we confirm their result through similar constraints. We identify a class of four-dimensional `zigzag' integrals which are perfectly adapted to describing the leading logarithmic discontinuity to all orders. We also observe that a bonus crossing symmetry of the preamplitude follows from the transformation properties of the Casimir operator. Combined with the zigzag integrals this allows us to construct a crossing symmetric function with the correct leading logarithmic discontinuities in all channels. From the two-loop result we extract an explicit expression for the two-loop correction to the anomalous dimensions of twist-four operators of generic spin which includes dependence on (alternating) nested harmonic sums up to weight three. We also revisit the prescription of the bulk-point limit of AdS amplitudes and show how it recovers the full flat-space amplitude, not just its discontinuity. With this extended notion of the bulk-point limit we reproduce the scale-dependent logarithmic threshold terms of type IIB string theory in flat-space.Comment: 51 pages, 1 ancillary fil

Quantum limits to center-of-mass measurements

We discuss the issue of measuring the mean position (center-of-mass) of a group of bosonic or fermionic quantum particles, including particle number fluctuations. We introduce a standard quantum limit for these measurements at ultra-low temperatures, and discuss this limit in the context of both photons and ultra-cold atoms. In the case of fermions, we present evidence that the Pauli exclusion principle has a strongly beneficial effect, giving rise to a 1/N scaling in the position standard-deviation -- as opposed to a $1/\sqrt{N}$ scaling for bosons. The difference between the actual mean-position fluctuation and this limit is evidence for quantum wave-packet spreading in the center-of-mass. This macroscopic quantum effect cannot be readily observed for non-interacting particles, due to classical pulse broadening. For this reason, we also study the evolution of photonic and matter-wave solitons, where classical dispersion is suppressed. In the photonic case, we show that the intrinsic quantum diffusion of the mean position can contribute significantly to uncertainties in soliton pulse arrival times. We also discuss ways in which the relatively long lifetimes of attractive bosons in matter-wave solitons may be used to demonstrate quantum interference between massive objects composed of thousands of particles.Comment: 12 pages, 6 figures. Submitted to PRA. Revised to include more references as well as a discussion of fermionic center-of-mas

Decoherence of Quantum-Enhanced Timing Accuracy

Quantum enhancement of optical pulse timing accuracy is investigated in the Heisenberg picture. Effects of optical loss, group-velocity dispersion, and Kerr nonlinearity on the position and momentum of an optical pulse are studied via Heisenberg equations of motion. Using the developed formalism, the impact of decoherence by optical loss on the use of adiabatic soliton control for beating the timing standard quantum limit [Tsang, Phys. Rev. Lett. 97, 023902 (2006)] is analyzed theoretically and numerically. The analysis shows that an appreciable enhancement can be achieved using current technology, despite an increase in timing jitter mainly due to the Gordon-Haus effect. The decoherence effect of optical loss on the transmission of quantum-enhanced timing information is also studied, in order to identify situations in which the enhancement is able to survive.Comment: 12 pages, 4 figures, submitte

Bootstrapping string theory on AdS5×S5_5 \times S^5

We make an ansatz for the Mellin representation of the four-point amplitude of half-BPS operators of arbitrary charges at order $\lambda^{-\frac{5}{2}}$ in an expansion around the supergravity limit. Crossing symmetry and a set of constraints on the form of the spectrum uniquely fix the amplitude and double-trace anomalous dimensions at this order. The results exhibit a number of natural patterns which suggest that the bootstrap approach outlined here will extend to higher orders in a simple way.Comment: 6 page

The Yangian origin of the Grassmannian integral

In this paper we analyse formulas which reproduce different contributions to scattering amplitudes in N=4 super Yang-Mills theory through a Grassmannian integral. Recently their Yangian invariance has been proved directly by using the explicit expression of the Yangian level-one generators. The specific cyclic structure of the form integrated over the Grassmannian enters in a crucial way in demonstrating the symmetry. Here we show that the Yangian symmetry fixes this structure uniquely.Comment: 26 pages. v2: typos corrected, published versio