134 research outputs found

    On the interaction of a single-photon wave packet with an excited atom

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    The interaction of a single-photon wave packet with an initially excited two-level atom in free space is studied in semiclassical and quantum approaches. It is shown that the final state of the field does not contain doubly occupied modes. The process of the atom's transition to the ground state may be accelerated, decelerated or even reversed by the incoming photon, depending on parameters. The spectrum of emitted radiation is close to the sum of the spectrum of the incoming single-photon wave packet and the natural line shape, with small and complicated deviations.Comment: 17 pages, 5 figure

    Monitoring tat peptide binding to TAR RNA by solid-state (31)P–(19)F REDOR NMR

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    Complexes of the HIV transactivation response element (TAR) RNA with the viral regulatory protein tat are of special interest due in particular to the plasticity of the RNA at this binding site and to the potential for therapeutic targeting of the interaction. We performed REDOR solid-state NMR experiments on lyophilized samples of a 29 nt HIV-1 TAR construct to measure conformational changes in the tat-binding site concomitant with binding of a short peptide comprising the residues of the tat basic binding domain. Peptide binding was observed to produce a nearly 4 Å decrease in the separation between phosphorothioate and 2′F labels incorporated at A27 in the upper helix and U23 in the bulge, respectively, consistent with distance changes observed in previous solution NMR studies, and with models showing significant rearrangement in position of bulge residue U23 in the bound-form RNA. In addition to providing long-range constraints on free TAR and the TAR–tat complex, these results suggest that in RNAs known to undergo large deformations upon ligand binding, (31)P–(19)F REDOR measurements can also serve as an assay for complex formation in solid-state samples. To our knowledge, these experiments provide the first example of a solid-state NMR distance measurement in an RNA–peptide complex

    Ultrathin 2 nm gold as ideal impedance-matched absorber for infrared light

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    Thermal detectors are a cornerstone of infrared (IR) and terahertz (THz) technology due to their broad spectral range. These detectors call for suitable broad spectral absorbers with minimalthermal mass. Often this is realized by plasmonic absorbers, which ensure a high absorptivity butonly for a narrow spectral band. Alternativly, a common approach is based on impedance-matching the sheet resistance of a thin metallic film to half the free-space impedance. Thereby, it is possible to achieve a wavelength-independent absorptivity of up to 50 %, depending on the dielectric properties of the underlying substrate. However, existing absorber films typicallyrequire a thickness of the order of tens of nanometers, such as titanium nitride (14 nm), whichcan significantly deteriorate the response of a thermal transducers. Here, we present the application of ultrathin gold (2 nm) on top of a 1.2 nm copper oxide seed layer as an effective IR absorber. An almost wavelength-independent and long-time stable absorptivity of 47(3) %, ranging from 2 μ\mum to 20 μ\mum, could be obtained and is further discussed. The presented gold thin-film represents analmost ideal impedance-matched IR absorber that allows a significant improvement of state-of-the-art thermal detector technology

    Ponderomotive entangling of atomic motions

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    We propose the use of ponderomotive forces to entangle the motions of different atoms. Two situations are analyzed: one where the atoms belong to the same optical cavity and interact with the same radiation field mode; the other where each atom is placed in own optical cavity and the output field of one cavity enters the other.Comment: Revtex file, five pages, two eps figure

    La riboflavina (vitamina B2) reduce el deterioro de pimientos mínimamente procesados

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    La riboflavina (vitamina B2) generalmente se reconoce como un aditivo seguro (GRAS). Se utiliza en alimentos para fortificar ciertos productos con bajo contenido natural o compensar las posibles pérdidas de vitaminas durante la elaboración. En este trabajo, se estudió el efecto de tratamientos por inmersión en riboflavina, previos al almacenamiento, en el mantenimiento de la calidad de pimiento verde recién cortado (Capsicum annum L). Inicialmente se ensayó la eficacia de diferentes concentraciones de riboflavina (0, control; 1; 10 y 100 μmol L-1) para reducir el deterioro en los bastones de pimiento cortado (5 × 1 cm) almacenados en una condición de abuso térmico, 8 ºC. El tratamiento de imersión por 5 min en 100 μmol L−1 de riboflavina controló eficazmente el deterioro de los pimientos y, por lo tanto, fue seleccionado para una evaluación adicional en pimientos almacenados a 4 ºC por 0, 6, 9 y 12 d.Laboratorio de Investigación en Productos AgroindustrialesConsejo Nacional de Investigaciones Científicas y TécnicasInstituto Nacional de Tecnología Agropecuari

    Alzheimer's Disease: a Review of its Visual System Neuropathology. Optical Coherence Tomography-a Potential Role As a Study Tool in Vivo

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    Alzheimer's disease (AD) is a prevalent, long-term progressive degenerative disorder with great social impact. It is currently thought that, in addition to neurodegeneration, vascular changes also play a role in the pathophysiology of the disease. Visual symptoms are frequent and are an early clinical manifestation; a number of psychophysiologic changes occur in visual function, including visual field defects, abnormal contrast sensitivity, abnormalities in color vision, depth perception deficits, and motion detection abnormalities. These visual changes were initially believed to be solely due to neurodegeneration in the posterior visual pathway. However, evidence from pathology studies in both animal models of AD and humans has demonstrated that neurodegeneration also takes place in the anterior visual pathway, with involvement of the retinal ganglion cells' (RGCs) dendrites, somata, and axons in the optic nerve. These studies additionally showed that patients with AD have changes in retinal and choroidal microvasculature. Pathology findings have been corroborated in in-vivo assessment of the retina and optic nerve head (ONH), as well as the retinal and choroidal vasculature. Optical coherence tomography (OCT) in particular has shown great utility in the assessment of these changes, and it may become a useful tool for early detection and monitoring disease progression in AD. The authors make a review of the current understanding of retinal and choroidal pathological changes in patients with AD, with particular focus on in-vivo evidence of retinal and choroidal neurodegenerative and microvascular changes using OCT technology.info:eu-repo/semantics/publishedVersio
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