Introduction to Nietzsche on Mind and Nature

This chapter provides summaries of the chapter of this book and introduces the major themes and debates addressed in the volume. Discussed are Nietzsche’s metaphysics; his philosophy of mind in light of contemporary views; the question of panpsychism of Beyond Good and Evil 36; the rejection of dualism in favour of monism, in particular a monism of value; Nietzsche’s positions on consciousness and embodied cognition in light of recent cognitive science; a conception of freedom and agency based on an intrinsically motivating; embodied sense of self-efficacy; a Nietzschean account of valuing understood as drive-induced affective orientations of which an agent approves; the idea of ressentiment conceived as a process of intentional, not reflectively strategic, self-deception about one’s own conscious mental states; and a defence of a Nietzschean naturalism

The feeling of doing - Nietzsche on agent causation

This article examines Nietzsche’s analysis of the phenomenology of agent causation. Sense of agent causation, our sense of self-efficacy, is tenacious because it originates, according to Nietzsche’s hypothesis, in the embodied and situated experience of effort in overcoming resistances. It arises at the level of the organism and is sustained by higher-order cognitive functions. Based on this hypothesis, Nietzsche regards the sense of self as emerging from a homeostatic system of drives and affects that unify such as to maintain self-efficacy levels. He relies on the same hypothesis to explain the emergence of an ascetic moral system and its specific, interpretive-affective ‘mechanism of willing’. The article aligns Nietzsche’s account of agent causation with Albert Bandura’s self-efficacy studies and Antonio Damasio’s recent account of self-systems as homeostatic systems

On the logic of values

This article argues that Nietzsche's transvaluation project refers not to a mere inversion or negation of a set of values but, instead, to a different conception of what a value is and how it functions. Traditional values function within a standard logical framework and claim legitimacy and bindingness based on exogenous authority with absolute extension. Nietzsche regards this framework as unnecessarily reductive in its attempted exclusion of contradiction and real opposition among competing values and proposes a nonstandard, dialetheic model of valuation

2.3 What is it like to recognize values? (The hard problem of value 2)

This article responds to three concerns regarding the viability of Nietzsche’s conception of value creation. Section I examines the claim that philosophy is unlikely to contribute to the creation of value. Section II argues that some puzzles regarding Nietzsche’s allegedly highest value of life-affirmation may require for a solution two different conceptions of life-affirmation: basic life-affirmationb and Life-affirmatione par excellence, which is both qualitatively different and based on a theoretically more demanding conception of life. Section three proposes that Nietzsche’s perspectivist method, which distinguishes between perspectival “knowing” and perspectival “objective” knowledge in GM III 12, may usefully be applied to the knowledge and recognition of differences in value perspectives and help improve our value practices

3.3 What Mary didn’t know about values (The hard problem of value 3)

This article answers some criticisms raised against How hard is it to create values? and offers a further formulation of the hard problem of value. Section 1 addresses the objection that Nietzsche’s criterion of life is too vague to serve as a useful value standard. Section 2 expands on the important idea of appreciating the difference among value perspectives. Sections 3 and 4 present the “hard problem of value” as a challenge for Nietzschean value agonism and value nihilism respectively. Section 5 offers a further formulation of the “hard problem of value”: a thought experiment about Mary, an expert, anti-realist value creator, whose values may or may not lack some qualities, analogous to Mary, the colour scientist of the “knowledge argument”

Ranking species in complex ecosystems through nestedness maximization

Identifying the rank of species in a complex ecosystem is a difficult task, since the rank of each species invariably depends on the interactions stipulated with other species through the adjacency matrix of the network. A common ranking method in economic and ecological networks is to sort the nodes such that the layout of the reordered adjacency matrix looks maximally nested with all nonzero entries packed in the upper left corner, called Nestedness Maximization Problem (NMP). Here we solve this problem by defining a suitable cost-energy function for the NMP which reveals the equivalence between the NMP and the Quadratic Assignment Problem, one of the most important combinatorial optimization problems, and use statistical physics techniques to derive a set of self-consistent equationswhose fixed point represents the optimal nodes’ rankings in an arbitrary bipartite mutualistic network. Concurrently, we present an efficient algorithm to solve the NMP that outperforms state-ofthe- art network-based metrics and genetic algorithms. Eventually, our theoretical framework may be easily generalized to study the relationship between ranking and network structure beyond pairwise interactions, e.g. in higher-order networks

Analyzing contrast in cryo-transmission electron microscopy: Comparison of electrostatic Zach phase plates and hole-free phase plates

Phase plates (PPs) are beneficial devices to improve the phase contrast of life-science objects in cryo-transmission electron microscopy (TEM). The development of the hole-free (HF) PP, which consists of a thin carbon film, has led to impressive results due to its ease in fabrication, implementation and application. However, the phase shift of the HFPP can be controlled only indirectly. The electrostatic Zach PP uses a strongly localized and adjustable electrostatic potential to generate well-defined and variable phase shifts between scattered and unscattered electrons. However, artifacts in phase-contrast TEM images are induced by the presence of the PP rod in the diffraction plane. We present a detailed analysis and comparison of the contrast-enhancing capabilities of both PP types and their emerging artifacts. For this purpose, cryo-TEM images of a standard T4-bacteriophage test sample were acquired with both PP types. Simulated images reproduce the experimental images well and substantially contribute to the understanding of contrast formation. An electrostatic Zach PP was used in this work to acquire cryo-electron tomograms with enhanced contrast, which are of similar quality as tomograms obtained by HFPP TEM

Sleep and Breathing Conference highlights 2023: a summary by ERS Assembly 4

During the SBC 2023, the latest research and clinical topics in sleep disordered breathing were presented. The sessions provided novel insights into sleep apnoea pathophysiology and treatment approaches, as well as in e-health and big data management. There were several opportunities for early career delegates to discover the latest scientific insights to different topics, as well as to benefit from networking opportunities, as presented in a previous Early Career Forum article [1]. This paper summarises some of the most relevant sessions and topics presented at the SBC, written by early career members from ERS Assembly 4info:eu-repo/semantics/publishedVersio