Review of Gandhaka Shodana using Damaru Yantra as described in Rasatarangini

The use of Gandhaka is widely brought out in the field of Rasashastra. There are many procedures mentioned for its Shodana which is practised abundantly in Ayurveda. Rasa Tarangini mentions one such unique method of purification which hasn’t been adopted till date. This method can be used in the preparation of Swarna Vanga, Makaradwaja etc. The method of Shodana involves the use of Damaru Yantra for its process and by following this procedure it prevents the presence of Pashanadi Doshas, avoids adherence of Milk/ Ghee as mentioned in other procedures of Shodana. This article mainly deals with the review of Shodana of Gandhaka as per Rasa Taran

Role of Prajasthapana Gana Siddha Ghrita Uttarbasti and oral yoga in the management of Vandhyatva with special reference to Bijotsarga (ovarian factor)

Motherhood is described as the pleasing punishment to woman. 10 to 15% marriages prove to be childless. Infertility is inability to conceive. Ayurveda may give a promising hand to cure the disease. In Ayurveda to achieve pregnancy Acharya Sushrut has given four essential factors i.e., Rutu, Kshetra, Ambu, Beeja. Also Acharya Chakrapani describe Prajasthapak Gana to treat infertility. Now a days Prajasthapak Gana Siddha Ghrita Uttarbasti is the key treatment in infertility. So therefore it has been decided to evaluate the efficacy of above treatment in Vandhyatva

Role of Vrushya Dravyas in the management of Oligospermia

Vajikarana is the important branch of Ayurved science. Vrushya Dravya belongs to Vajikaran branch. In Ayurveda due importance is given to Ahara Dravya. Ahara Dravyas are mainly responsible for the healthy production of Saptadhatu. Now a days due to consumption of junk food, lifestyle disorder, stress factor directly effect on human body. As per Ayurveda Vrushya Dravyas are mainly responsible for Spermatogenesis

A Review on Anupana for Saptadhatus of Rasashastra

Ayurveda is the science which is practiced all over the world since 5000 years. This science is popular because of its unique concepts and treatment methods. Rasashastra is a specialized branch of Ayurveda in which certain minerals, metals and organic compounds are used for the treatment purpose. These substances will be subjected to various purificatory and incineration processes to remove the toxicity before internal administration. Rasoushadhis are famous because of their faster actions and minimal dosage. These medicines should be administered with proper adjuvants i.e. Anupana which can increase the potency of the medicine to attain good result. In Rasashastra, Suvarna, Tamra, Rajata, Naga, Vanga, Yasada, Loha are the seven important Dhatus which are commonly used in Bhasma form for treatment. These should be administered as a treatment modality with a specific Anupana indicated for various diseases distinctively there by proving to have its maximum effect with it. Hence this article deals with the classical Anupanas which has to be used while administering Bhasmas

A Review on the concept of Anupana in Ayurveda

Ayurveda which is the science of life is famous all over the world because of its unique concepts and practising methods. The main aim of Ayurveda is to attain Dhatusamyakriya, and through that maintain the Swasthyata of the body. Anupana is one of the unique concept of Ayurveda which plays an important role in the treatment. Anupana is that material which is consumed along with food or medicine. It can increase the palatability of the food or medicine, can improve the digestion and absorption and also act as a vehicle which carries the drug to their target site. Hence this article deals with the importance of Anupana in the Ayurvedic practise

An Analytical Study on Pippalyasava

Pippalyasava is one of the important and common preparation used by practitioners for various ailments. Lot of references are available regarding Pippalyasava in classics and are abundant in market. As a part of study Pippalyasava is prepared and observed for 6 months also these samples were subjected to following analytical parameters like organoleptic characters, physical characters, chemical characters and TLC during 2nd month and 6th month to ensure the quality of the prepared sample

A clinical study to evaluate the efficacy of Chitrakadi Churna in Kaphaja Kasa

As per the view of Ayurveda our body is composed of Dosha, Dhatu, Mala. Vata, Pitta, Kapha are the main constituents of the body and when they get vitiated they are the cause of diseases in the body. According to this theory Kaphaja Kasa is explained in Samhitas. Kaphaja Kasa is a disease of Pranvahastrotasa. If neglected it results in to poor prognosis and causes severe complications like Shwasa, Rajayshma, Raktapitta etc. So it is necessary to treat Kaphaja Kasa as early. So in present study it is an effort to evaluate the efficacy of Chitrakadi Churna in Kaphaja Kasa

Genome-wide association analysis reveals QTL and candidate mutations involved in white spotting in cattle

International audienceAbstractBackgroundWhite spotting of the coat is a characteristic trait of various domestic species including cattle and other mammals. It is a hallmark of Holstein–Friesian cattle, and several previous studies have detected genetic loci with major effects for white spotting in animals with Holstein–Friesian ancestry. Here, our aim was to better understand the underlying genetic and molecular mechanisms of white spotting, by conducting the largest mapping study for this trait in cattle, to date.ResultsUsing imputed whole-genome sequence data, we conducted a genome-wide association analysis in 2973 mixed-breed cows and bulls. Highly significant quantitative trait loci (QTL) were found on chromosomes 6 and 22, highlighting the well-established coat color genes KIT and MITF as likely responsible for these effects. These results are in broad agreement with previous studies, although we also report a third significant QTL on chromosome 2 that appears to be novel. This signal maps immediately adjacent to the PAX3 gene, which encodes a known transcription factor that controls MITF expression and is the causal locus for white spotting in horses. More detailed examination of these loci revealed a candidate causal mutation in PAX3 (p.Thr424Met), and another candidate mutation (rs209784468) within a conserved element in intron 2 of MITF transcripts expressed in the skin. These analyses also revealed a mechanistic ambiguity at the chromosome 6 locus, where highly dispersed association signals suggested multiple or multiallelic QTL involving KIT and/or other genes in this region.ConclusionsOur findings extend those of previous studies that reported KIT as a likely causal gene for white spotting, and report novel associations between candidate causal mutations in both the MITF and PAX3 genes. The sizes of the effects of these QTL are substantial, and could be used to select animals with darker, or conversely whiter, coats depending on the desired characteristics

PREVALENCE OF PULMONARY HYPERTENSION IN PATIENTS OF CHRONIC KIDNEY DISEASE IN WESTERN RAJASTHAN: A CROSS SECTIONAL STUDY: PULMONARY HYPERTENSION IN PATIENTS OF CHRONIC KIDNEY DISEASE

Objective: Due to limited study in our region on pulmonary hypertension in chronic kidney disease patients, we planned a study to detect the prevalence of Pulmonary hypertension in patients with chronic kidney disease. An additional objective was to study an association between pulmonary hypertension and CKD stage if any. Methods: Hospital based cross-sectional study was conducted on 108 diagnosed cases of CKD (according to different stages based on GFR) and age more than 18 years. All data collected and analyzed by SPSS software. Co-relation co-efficient was used to find out correlation. Results: Prevalence of pulmonary hypertension in CKD patients was 15.74%. 47.06% patients were mild, 41.18% patients were moderate and 11.11% patients were in severe pulmonary hypertension. The association between pulmonary hypertension and CKD stage was found statically insignificant. In linear regression between age, CKD stage & duration and PAH was found statistically insignificant. Conclusion: Prevalence of pulmonary hypertension in CKD patients was 15.74%. Pulmonary hypertension had positive correlation with stage of CKD, duration of CKD and age of patients