Concept of Gudavarti w.s.r. to Rectal Suppositories

Suppositories are solid dosage preparations prepared by moulding or compression intended for its insertion into body orifices like the rectum, vagina and the urethra. Suppositories melts and exhibits local or systemic effects. Rectal route of drug administration encorporates absorption of the drug through rectal blood vessels to exhibit desired therapeutic action. Rectal suppositories can be the best choice for drugs that are either too irritative to the gut or more effective when partly metabolized by the liver. Varti Kalpana is a variant of Vati Kalpana with similar method of preparation. Varti are solid and are wick shaped with tapering ends intended for easy insertion into body orifices. Based on the site of insertion, Ayurveda explains Guda Varti, Yoni Varti and Sishna Varti. Different types of Varti have been explained based on its size, site of application, composition and action. Various methods of its preparation has been explained both in the classical literature and in contemporary science. Rectal suppositories offer patients an option that is less invasive and less discomforting and which proves to be a convenient drug delivery option especially in patients with rectal complaints. It can be appreciated that Varti Kalpana was used in practice since ancient times and that recent advancement of suppositories is just its slight modification. A detailed study of both the Varti and the suppositories help us draw many similarities between the two

Maggot debridement therapy an Ayurvedic understanding

Maggot debridement therapy also known as larva therapy, bio debridement or bio surgery, is practiced widely in Western countries. It manages to clean the wound by removing dead and infected tissue (‘debridement’), disinfecting the wound (kill bacteria).[1] The available references say that this procedure was started during the late 1920s by William Bear, at Johns Hopkins University in Baltimore, Maryland. He first studied lifecycle of maggots, successfully treated the wounds and published a series of articles. And he recommended to rear and disinfect the maggots and he is the one to recommend application of specific species of blow flies. This method of Wound debridement has been explained in our classical treaties Sushruta Samhita by The Father of Indian surgery - Acharya Sushruta in the name of Krimi Utpattikara Chikitsa in the context of Arbuda

Role of Apamarga Yavakshara in the management of Mutrashmari - A Conceptual Study

Mutrashmari is one of the most common disorders of the Mutravaha Srotas. It is one of the Astamahagada and considered as "Yama” because sometimes it causes acute excruciating pain.[1] In contemporary medical science it is correlated with urolithiasis. Symptoms in general include radiating pain from loin to groin, hematuria, burning micturition, malaise. Prevalence of Urolithiasis varies according to geographical distribution, sex and age. The treatment modalities of urolithiasis in conventional science are conservative medications and surgical procedures which are expensive, involve invasive treatments, needs hospitalization and in most of the cases recurrence rate is high. Ayurveda explains variety of Yogas for the management of Mutrashmari. A combination of Apamarga and Yava Kshara is indicated in Mutrashmari as per Rasatarangini.[2] So this study is taken up, to explore the combined effect of Apamarga and Yava Kshara in Mutrashmari keeping in view the shortcomings of different modern medical treatments