18,253 research outputs found
Measuring device Patent
Expulsion and measuring device for determining quantity of liquid in tank under conditions of weightlessnes
Planetological implications of mass loss from the early Sun
The element lithium is observed to be underabundant in the Sun by a factor of approx. equal to 100. To account for this depletion, Boothroyd et al. (Ap. J., in press 1991) proposed a model in which the Sun's zero-age-main-sequence mass was approx. 1.1 solar magnitude. If this is the explanation for the lithium depletion, then astronomical observations of F/G dwarfs in clusters suggest that the timescale for mass loss is approx. equal to 0.6 Gyr. Assuming this approximate timescale, the authors investigated several planetological implications of the astrophysical model
Word Adjacency Graph Modeling: Separating Signal From Noise in Big Data
There is a need to develop methods to analyze Big Data to inform patient-centered interventions for better health outcomes. The purpose of this study was to develop and test a method to explore Big Data to describe salient health concerns of people with epilepsy. Specifically, we used Word Adjacency Graph modeling to explore a data set containing 1.9 billion anonymous text queries submitted to the ChaCha question and answer service to (a) detect clusters of epilepsy-related topics, and (b) visualize the range of epilepsy-related topics and their mutual proximity to uncover the breadth and depth of particular topics and groups of users. Applied to a large, complex data set, this method successfully identified clusters of epilepsy-related topics while allowing for separation of potentially non-relevant topics. The method can be used to identify patient-driven research questions from large social media data sets and results can inform the development of patient-centered interventions
Calculating effective resistances on underlying networks of association schemes
Recently, in Refs. \cite{jsj} and \cite{res2}, calculation of effective
resistances on distance-regular networks was investigated, where in the first
paper, the calculation was based on stratification and Stieltjes function
associated with the network, whereas in the latter one a recursive formula for
effective resistances was given based on the Christoffel-Darboux identity. In
this paper, evaluation of effective resistances on more general networks which
are underlying networks of association schemes is considered, where by using
the algebraic combinatoric structures of association schemes such as
stratification and Bose-Mesner algebras, an explicit formula for effective
resistances on these networks is given in terms of the parameters of
corresponding association schemes. Moreover, we show that for particular
underlying networks of association schemes with diameter such that the
adjacency matrix possesses distinct eigenvalues, all of the other
adjacency matrices , can be written as polynomials of ,
i.e., , where is not necessarily of degree . Then, we use
this property for these particular networks and assume that all of the
conductances except for one of them, say , are zero to give a
procedure for evaluating effective resistances on these networks. The
preference of this procedure is that one can evaluate effective resistances by
using the structure of their Bose-Mesner algebra without any need to know the
spectrum of the adjacency matrices.Comment: 41 page
Sheep programmes for Esperance settlers with limited finance
FARMING in the Esperance region has now passed through the phase of experimentation into the phase of consolidation.
But not all new settlers are prosperous.
On occasions, a lifetime ambition to own and operate a farm has ended in failure because the settler has been forced through economic circumstances to give up his block.
Too often this follows the unequal struggle of trying to develop a block with too little capital
Wheat in development programmes for new Esperance farmers
IN the December, 1967, issue of the Journal of Agriculture, we reported on five development budgets for the Esperance region.
The aim of the exercise was to find out if a new settler concentrating on sheep, with $20,000 available for development after acquisition of land, could make a reasonable living for himself and his family while developing his farm
Assessment of the visibility impairment caused by the emissions from the proposed power plant at Boron, California
The current atmospheric conditions and visibility were modeled, and the effect of the power plant effluent was then added to determine its influence upon the prevailing visibility; the actual reduction in visibility being a function of meteorological conditions and observer-plume-target geometry. In the cases investigated, the perceptibility of a target was reduced by a minimum of 10 percent and a maximum of 100 percent. This significant visual impact would occur 40 days per year in the Edwards area with meteorological conditions such as to cause some visual impact 80 days per year
High-flux beam source for cold, slow atoms or molecules
We demonstrate and characterize a high-flux beam source for cold, slow atoms
or molecules. The desired species is vaporized using laser ablation, then
cooled by thermalization in a cryogenic cell of buffer gas. The beam is formed
by particles exiting a hole in the buffer gas cell. We characterize the
properties of the beam (flux, forward velocity, temperature) for both an atom
(Na) and a molecule (PbO) under varying buffer gas density, and discuss
conditions for optimizing these beam parameters. Our source compares favorably
to existing techniques of beam formation, for a variety of applications.Comment: 5 Pages, 4 figure
Computer-guided concentration-controlled trials in autoimmune disorders
A randomized concentration-controlled clinical trial (RCCCT) is an alternate experimental design to the standard dose-controlled study. In a RCCCT, patients are randomly assigned to predefined plasma or blood drug concentration ranges (low, medium, and high). With the caveat that concentration ranges are sufficiently separated, this design should enhance the ability to discover important concentration response relationships. FK-506, a potent and promising immunosuppressive agent for prevention and treatment of graft rejection, has shown significant clinical activity in some immune-mediated disorders. To implement the RCCCT design, a novel FK-506 intelligent dosing system (IDS) was used to guide all doses to prospectively achieve the target concentration range specified in the study protocol. Patients enrolled in these trials suffered from a variety of autoimmune disorders, including multiple sclerosis, primary biliary cirrhosis, psoriasis, autoimmune chronic active hepatitis, and nephrotic syndrome. We observed excellent predictive performance of the IDS for all patients. The accuracy (mean prediction error) of the IDS was −0.022 ng/ml and the precision (standard deviation of the prediction error) was 0.119 ng/ml. Thus, the IDS is both accurate and reproducible for autoimmune patients. We conclude that the RCCCT design, guided by an accurate and precise IDS, is an informative and cost-effective approach for evaluation of efficacy and safety of effective but highly toxic agents. © 1993 Raven Press, Ltd., New York
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