18,253 research outputs found

    Measuring device Patent

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    Expulsion and measuring device for determining quantity of liquid in tank under conditions of weightlessnes

    Planetological implications of mass loss from the early Sun

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    The element lithium is observed to be underabundant in the Sun by a factor of approx. equal to 100. To account for this depletion, Boothroyd et al. (Ap. J., in press 1991) proposed a model in which the Sun's zero-age-main-sequence mass was approx. 1.1 solar magnitude. If this is the explanation for the lithium depletion, then astronomical observations of F/G dwarfs in clusters suggest that the timescale for mass loss is approx. equal to 0.6 Gyr. Assuming this approximate timescale, the authors investigated several planetological implications of the astrophysical model

    Word Adjacency Graph Modeling: Separating Signal From Noise in Big Data

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    There is a need to develop methods to analyze Big Data to inform patient-centered interventions for better health outcomes. The purpose of this study was to develop and test a method to explore Big Data to describe salient health concerns of people with epilepsy. Specifically, we used Word Adjacency Graph modeling to explore a data set containing 1.9 billion anonymous text queries submitted to the ChaCha question and answer service to (a) detect clusters of epilepsy-related topics, and (b) visualize the range of epilepsy-related topics and their mutual proximity to uncover the breadth and depth of particular topics and groups of users. Applied to a large, complex data set, this method successfully identified clusters of epilepsy-related topics while allowing for separation of potentially non-relevant topics. The method can be used to identify patient-driven research questions from large social media data sets and results can inform the development of patient-centered interventions

    Calculating effective resistances on underlying networks of association schemes

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    Recently, in Refs. \cite{jsj} and \cite{res2}, calculation of effective resistances on distance-regular networks was investigated, where in the first paper, the calculation was based on stratification and Stieltjes function associated with the network, whereas in the latter one a recursive formula for effective resistances was given based on the Christoffel-Darboux identity. In this paper, evaluation of effective resistances on more general networks which are underlying networks of association schemes is considered, where by using the algebraic combinatoric structures of association schemes such as stratification and Bose-Mesner algebras, an explicit formula for effective resistances on these networks is given in terms of the parameters of corresponding association schemes. Moreover, we show that for particular underlying networks of association schemes with diameter dd such that the adjacency matrix AA possesses d+1d+1 distinct eigenvalues, all of the other adjacency matrices AiA_i, i≠0,1i\neq 0,1 can be written as polynomials of AA, i.e., Ai=Pi(A)A_i=P_i(A), where PiP_i is not necessarily of degree ii. Then, we use this property for these particular networks and assume that all of the conductances except for one of them, say c≡c1=1c\equiv c_1=1, are zero to give a procedure for evaluating effective resistances on these networks. The preference of this procedure is that one can evaluate effective resistances by using the structure of their Bose-Mesner algebra without any need to know the spectrum of the adjacency matrices.Comment: 41 page

    Sheep programmes for Esperance settlers with limited finance

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    FARMING in the Esperance region has now passed through the phase of experimentation into the phase of consolidation. But not all new settlers are prosperous. On occasions, a lifetime ambition to own and operate a farm has ended in failure because the settler has been forced through economic circumstances to give up his block. Too often this follows the unequal struggle of trying to develop a block with too little capital

    Wheat in development programmes for new Esperance farmers

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    IN the December, 1967, issue of the Journal of Agriculture, we reported on five development budgets for the Esperance region. The aim of the exercise was to find out if a new settler concentrating on sheep, with $20,000 available for development after acquisition of land, could make a reasonable living for himself and his family while developing his farm

    Assessment of the visibility impairment caused by the emissions from the proposed power plant at Boron, California

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    The current atmospheric conditions and visibility were modeled, and the effect of the power plant effluent was then added to determine its influence upon the prevailing visibility; the actual reduction in visibility being a function of meteorological conditions and observer-plume-target geometry. In the cases investigated, the perceptibility of a target was reduced by a minimum of 10 percent and a maximum of 100 percent. This significant visual impact would occur 40 days per year in the Edwards area with meteorological conditions such as to cause some visual impact 80 days per year

    High-flux beam source for cold, slow atoms or molecules

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    We demonstrate and characterize a high-flux beam source for cold, slow atoms or molecules. The desired species is vaporized using laser ablation, then cooled by thermalization in a cryogenic cell of buffer gas. The beam is formed by particles exiting a hole in the buffer gas cell. We characterize the properties of the beam (flux, forward velocity, temperature) for both an atom (Na) and a molecule (PbO) under varying buffer gas density, and discuss conditions for optimizing these beam parameters. Our source compares favorably to existing techniques of beam formation, for a variety of applications.Comment: 5 Pages, 4 figure

    Computer-guided concentration-controlled trials in autoimmune disorders

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    A randomized concentration-controlled clinical trial (RCCCT) is an alternate experimental design to the standard dose-controlled study. In a RCCCT, patients are randomly assigned to predefined plasma or blood drug concentration ranges (low, medium, and high). With the caveat that concentration ranges are sufficiently separated, this design should enhance the ability to discover important concentration response relationships. FK-506, a potent and promising immunosuppressive agent for prevention and treatment of graft rejection, has shown significant clinical activity in some immune-mediated disorders. To implement the RCCCT design, a novel FK-506 intelligent dosing system (IDS) was used to guide all doses to prospectively achieve the target concentration range specified in the study protocol. Patients enrolled in these trials suffered from a variety of autoimmune disorders, including multiple sclerosis, primary biliary cirrhosis, psoriasis, autoimmune chronic active hepatitis, and nephrotic syndrome. We observed excellent predictive performance of the IDS for all patients. The accuracy (mean prediction error) of the IDS was −0.022 ng/ml and the precision (standard deviation of the prediction error) was 0.119 ng/ml. Thus, the IDS is both accurate and reproducible for autoimmune patients. We conclude that the RCCCT design, guided by an accurate and precise IDS, is an informative and cost-effective approach for evaluation of efficacy and safety of effective but highly toxic agents. © 1993 Raven Press, Ltd., New York
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