2,917 research outputs found
The Coulomb Sum and Proton-Proton Correlations in Few-Body Nuclei
In simple models of the nuclear charge operator, measurements of the Coulomb
sum and the charge form factor of a nucleus directly determine the
proton-proton correlations. We examine experimental results obtained for
few-body nuclei at Bates and Saclay using models of the charge operator that
include both one- and two-body terms. Previous analyses using one-body terms
only have failed to reproduce experimental results. However, we find that the
same operators which have been used to successfully describe the charge form
factors also produce substantial agreement with measurements of the Coulomb
sum.Comment: 11 pages, Revtex version 3.0 with 3 Postscript figures appended, ANL
preprint PHY-7473-TH-9
The coronal fricative problem
This paper examines a range of predicted versus attested error patterns involving coronal fricatives (e.g. [s, z, θ, ð]) as targets and repairs in the early sound systems of monolingual English-acquiring children. Typological results are reported from a cross-sectional study of 234 children with phonological delays (ages 3 years; 0 months to 7;9). Our analyses revealed different instantiations of a putative developmental conspiracy within and across children. Supplemental longitudinal evidence is also presented that replicates the cross-sectional results, offering further insight into the life-cycle of the conspiracy. Several of the observed typological anomalies are argued to follow from a modified version of Optimality Theory with Candidate Chains (McCarthy, 2007).National Institutes of Health DC00433, RR7031K, DC00076, DC001694 (PI: Gierut
Critical Velocity of Vortex Nucleation in Rotating Superfluid 3He-A
We have measured the critical velocity v_c at which 3He-A in a rotating
cylinder becomes unstable against the formation of quantized vortex lines with
continuous (singularity-free) core structure. We find that v_c is distributed
between a maximum and minimum limit, which we ascribe to a dependence on the
texture of the orbital angular momentum l(r) in the cylinder. Slow cool down
through T_c in rotation yields l(r) textures for which the measured v_c's are
in good agreement with the calculated instability of the expected l texture.Comment: 4 pages, 3 figure
Theory of High-Tc Superconductivity: Accurate Predictions of Tc
The superconducting transition temperatures of high-Tc compounds based on
copper, iron, ruthenium and certain organic molecules are discovered to be
dependent on bond lengths, ionic valences, and Coulomb coupling between
electronic bands in adjacent, spatially separated layers [1]. Optimal
transition temperature, denoted as T_c0, is given by the universal expression
; is the spacing between interacting
charges within the layers, \zeta is the distance between interacting layers and
\Lambda is a universal constant, equal to about twice the reduced electron
Compton wavelength (suggesting that Compton scattering plays a role in
pairing). Non-optimum compounds in which sample degradation is evident
typically exhibit Tc < T_c0. For the 31+ optimum compounds tested, the
theoretical and experimental T_c0 agree statistically to within +/- 1.4 K. The
elemental high Tc building block comprises two adjacent and spatially separated
charge layers; the factor e^2/\zeta arises from Coulomb forces between them.
The theoretical charge structure representing a room-temperature superconductor
is also presented.Comment: 7 pages 5 references, 6 figures 1 tabl
Power of knowledge in executing household water treatment programs globally
This paper presents a case study of five organizations from five countries: Haiti, El Salvador, India, the Philippines
and Pakistan, demonstrating that knowledge transfer can be a catalyst for locally-driven water programs
for the poor. Each organization received training and technical consulting from the Centre for Affordable
Water and Sanitation Technology on Project Implementation for the Biosand Filter. Each then established
an independent project resulting in cleaner water for 156,000 people in six years, and widespread biosand
filter acceptance among users. Lessons learned are that knowledge transfer can result in effective, sustainable
and scaleable technology implementation; transfer takes place one person at a time, making education
at all levels crucial; pilots/demonstrations are essential motivators to technology adoption; involvement of
mainstream government can result in faster implementation and widespread acceptance; and technology
training is not enough. Organizations need to learn how to plan, implement and monitor programs
A unified approach for the solution of the Fokker-Planck equation
This paper explores the use of a discrete singular convolution algorithm as a
unified approach for numerical integration of the Fokker-Planck equation. The
unified features of the discrete singular convolution algorithm are discussed.
It is demonstrated that different implementations of the present algorithm,
such as global, local, Galerkin, collocation, and finite difference, can be
deduced from a single starting point. Three benchmark stochastic systems, the
repulsive Wong process, the Black-Scholes equation and a genuine nonlinear
model, are employed to illustrate the robustness and to test accuracy of the
present approach for the solution of the Fokker-Planck equation via a
time-dependent method. An additional example, the incompressible Euler
equation, is used to further validate the present approach for more difficult
problems. Numerical results indicate that the present unified approach is
robust and accurate for solving the Fokker-Planck equation.Comment: 19 page
Strong laws of large numbers for sub-linear expectations
We investigate three kinds of strong laws of large numbers for capacities
with a new notion of independently and identically distributed (IID) random
variables for sub-linear expectations initiated by Peng. It turns out that
these theorems are natural and fairly neat extensions of the classical
Kolmogorov's strong law of large numbers to the case where probability measures
are no longer additive. An important feature of these strong laws of large
numbers is to provide a frequentist perspective on capacities.Comment: 10 page
Phenomenology of the Deuteron Electromagnetic Form Factors
A rigorous extraction of the deuteron charge form factors from tensor
polarization data in elastic electron-deuteron scattering, at given values of
the 4-momentum transfer, is presented. Then the world data for elastic
electron-deuteron scattering is used to parameterize, in three different ways,
the three electromagnetic form factors of the deuteron in the 4-momentum
transfer range 0-7 fm^-1. This procedure is made possible with the advent of
recent polarization measurements. The parameterizations allow a
phenomenological characterization of the deuteron electromagnetic structure.
They can be used to remove ambiguities in the form factors extraction from
future polarization data.Comment: 18 pages (LaTeX), 2 figures Feb. 25: minor changes of content and in
Table
Pten loss promotes MAPK pathway dependency in HER2/neu breast carcinomas
Loss of the tumor suppressor gene PTEN is implicated in breast cancer progression and resistance to targeted therapies, and is thought to promote tumorigenesis by activating PI3K signaling. In a transgenic model of breast cancer, Pten suppression using a tetracycline-regulatable short hairpin (sh)RNA cooperates with human epidermal growth factor receptor 2 (HER2/neu), leading to aggressive and metastatic disease with elevated signaling through PI3K and, surprisingly, the mitogen-activated protein kinase (MAPK) pathway. Restoring Pten function is sufficient to down-regulate both PI3K and MAPK signaling and triggers dramatic tumor regression. Pharmacologic inhibition of MAPK signaling produces similar effects to Pten restoration, suggesting that the MAPK pathway contributes to the maintenance of advanced breast cancers harboring Pten loss
Specialized stellate cells offer a privileged route for rapid water flux in Drosophila renal tubule
Insects are highly successful, in part through an excellent ability to osmoregulate. The renal (Malpighian) tubules can secrete fluid faster on a per-cell basis than any other epithelium, but the route for these remarkable water fluxes has not been established. In Drosophila melanogaster, we show that 4 genes of the major intrinsic protein family are expressed at a very high level in the fly renal tissue: the aquaporins (AQPs) Drip and Prip and the aquaglyceroporins Eglp2 and Eglp4. As predicted from their structure, and by their transport function by expressing these proteins in Xenopus oocytes, Drip, Prip, and Eglp2 show significant and specific water permeability, whereas Eglp2 and Eglp4 show very high permeability to glycerol and urea. Knockdowns of any of these genes result in impaired hormone-induced fluid secretion. The Drosophila tubule has 2 main secretory cell types: active cation-transporting principal cells, wherein the aquaglyceroporins localize to opposite plasma membranes, and small stellate cells, the site of the chloride shunt conductance, with these AQPs localizing to opposite plasma membranes. This suggests a model in which osmotically obliged water flows through the stellate cells. Consistent with this model, fluorescently labeled dextran, an in vivo marker of membrane water permeability, is trapped in the basal infoldings of the stellate cells after kinin diuretic peptide stimulation, confirming that these cells provide the major route for transepithelial water flux. The spatial segregation of these components of epithelial water transport may help to explain the unique success of the higher insects in regulating their internal environments
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