1,582 research outputs found
Recommended from our members
Using data visualization in creativity workshops: a new tool in the designer's kit
Creativity workshops have proved effective in drawing out unexpected requirements and giving form to participants' novel ideas. Here, we introduce a new addition to the workshop designer's toolkit: interactive data visualization, used as stimuli to prompt insight and inspire creativity. We first describe a pilot study in which we compare the effectiveness of two different styles of data visualization. Here we found that a less ambiguous style was more effective in supporting idea generation. Following this, we report a case study in which we employ data visualization within a service design workshop, where participants gain insights that are later realized in design ideas
Phonon Band Structure and Thermal Transport Correlation in a Layered Diatomic Crystal
To elucidate the relationship between a crystal's structure, its thermal
conductivity, and its phonon dispersion characteristics, an analysis is
conducted on layered diatomic Lennard-Jones crystals with various mass ratios.
Lattice dynamics theory and molecular dynamics simulations are used to predict
the phonon dispersion curves and the thermal conductivity. The layered
structure generates directionally dependent thermal conductivities lower than
those predicted by density trends alone. The dispersion characteristics are
quantified using a set of novel band diagram metrics, which are used to assess
the contributions of acoustic phonons and optical phonons to the thermal
conductivity. The thermal conductivity increases as the extent of the acoustic
modes increases, and decreases as the extent of the stop bands increases. The
sensitivity of the thermal conductivity to the band diagram metrics is highest
at low temperatures, where there is less anharmonic scattering, indicating that
dispersion plays a more prominent role in thermal transport in that regime. We
propose that the dispersion metrics (i) provide an indirect measure of the
relative contributions of dispersion and anharmonic scattering to the thermal
transport, and (ii) uncouple the standard thermal conductivity
structure-property relation to that of structure-dispersion and
dispersion-property relations, providing opportunities for better understanding
of the underlying physical mechanisms and a potential tool for material design.Comment: 30 pages, 10 figure
Low Luminosity States of the Black Hole Candidate GX~339--4. II. Timing Analysis
Here we present timing analysis of a set of eight Rossi X-ray Timing Explorer
(RXTE) observations of the black hole candidate GX 339-4 that were taken during
its hard/low state. On long time scales, the RXTE All Sky Monitor data reveal
evidence of a 240 day periodicity, comparable to timescales expected from
warped, precessing accretion disks. On short timescales all observations save
one show evidence of a persistent f approximately equal to 0.3 Hz QPO. The
broad band (10^{-3}-10^2 Hz) power appears to be dominated by two independent
processes that can be modeled as very broad Lorentzians with Q approximately
less than 1. The coherence function between soft and hard photon variability
shows that if these are truly independent processes, then they are individually
coherent, but they are incoherent with one another. This is evidenced by the
fact that the coherence function between the hard and soft variability is near
unity between 0.005-10 Hz but shows evidence of a dip at f approximately equal
to 1 Hz. This is the region of overlap between the broad Lorentzian fits to the
PSD. Similar to Cyg X-1, the coherence also drops dramatically at frequencies
approximately greater than 10 Hz. Also similar to Cyg X-1, the hard photon
variability is seen to lag the soft photon variability with the lag time
increasing with decreasing Fourier frequency. The magnitude of this time lag
appears to be positively correlated with the flux of GX 339-4. We discuss all
of these observations in light of current theoretical models of both black hole
spectra and temporal variability.Comment: To Appear in the AStrophysical Journa
On the Absorption of X-rays in the Interstellar Medium
We present an improved model for the absorption of X-rays in the ISM intended
for use with data from future X-ray missions with larger effective areas and
increased energy resolution such as Chandra and XMM, in the energy range above
100eV. Compared to previous work, our formalism includes recent updates to the
photoionization cross section and revised abundances of the interstellar
medium, as well as a treatment of interstellar grains and the H2molecule. We
review the theoretical and observational motivations behind these updates and
provide a subroutine for the X-ray spectral analysis program XSPEC that
incorporates our model.Comment: ApJ, in press, for associated software see
http://astro.uni-tuebingen.de/nh
Evidence for anisotropic polar nanoregions in relaxor PMN: A neutron study of the elastic constants and anomalous TA phonon damping
We use neutron scattering to characterize the acoustic phonons in the relaxor
PMN and demonstrate the presence of an anisotropic damping mechanism directly
related to short-range, polar correlations. For a large range of temperatures
above Tc ~ 210, K, where dynamic polar correlations exist, acoustic phonons
propagating along [1\bar{1}0] and polarized along [110] (TA2 phonons) are
overdamped and softened across most of the Brillouin zone. By contrast,
acoustic phonons propagating along [100] and polarized along [001] (TA1
phonons) are overdamped and softened for only a limited range of wavevectors.
The anisotropy and temperature dependence of the acoustic phonon energy
linewidth are directly correlated with the elastic diffuse scattering,
indicating that polar nanoregions are the cause of the anomalous behavior. The
damping and softening vanish for q -> 0, i.e. for long-wavelength acoustic
phonons, which supports the notion that the anomalous damping is a result of
the coupling between the relaxational component of the diffuse scattering and
the harmonic TA phonons. Therefore, these effects are not due to large changes
in the elastic constants with temperature because the elastic constants
correspond to the long-wavelength limit. We compare the elastic constants we
measure to those from Brillouin scattering and to values reported for pure PT.
We show that while the values of C44 are quite similar, those for C11 and C12
are significantly less in PMN and result in a softening of (C11-C12) over PT.
There is also an increased elastic anisotropy (2C44/(C11-C12)) versus that in
PT. These results suggest an instability to TA2 acoustic fluctuations in
relaxors. We discuss our results in the context of the debate over the
"waterfall" effect and show that they are inconsistent with TA-TO phonon
coupling or other models that invoke the presence of a second optic mode.Comment: (21 pages, 16 figures, to be published in Physical Review B
Charged and Pseudoscalar Higgs production at a Muon Collider
We consider single charged Higgs () and pseudoscalar Higgs ()
production in association with a gauge boson at colliders. We find
that the tree-level t-channel and s-channel contributions to are enhanced for large values of , allowing
sizeable cross-sections whose analogies at colliders would be very
small. These processes provide attractive new ways of producing such particles
at colliders and are superior to the conventional methods in
regions of parameter space.Comment: 11 pages Latex, 5 figures, formulae added in sections 2.2 and 2.3,
extra discussion in section 2.3, references adde
Predicting sexual problems in women: The relevance of sexual excitation and sexual inhibition
This is the post-print version of the article. The official published version can be obtained from the link below.Data from a non-clinical sample of 540 heterosexual women were used to examine the relationships between scores on the Sexual Excitation/Sexual Inhibition Inventory for Women (SESII-W) and ratings of current sexual problems, lifetime arousal difficulty, lifetime orgasm difficulty, and lifetime problems with low sexual interest. Multiple regression analyses also included several demographic/background variables as predictors: age, full-time employment, completed college, children in household, married, health ratings, importance of sex, and whether the woman was in a sexual relationship. The strongest statistical predictors of both current and lifetime sexual problems were the SESII-W inhibition factors Arousal Contingency and Concerns about Sexual Function. Demographic factors did not feature largely in any of the models predicting sexual problems even when statistically significant relationships were found. If future research supports the predictive utility of the SESII-W in identifying women who are more likely to experience sexual difficulties, these scales may be used as prognostic factors in treatment studies.This study was funded, in part, by a grant from the Lilly Centre for Women's Health
Dual-barrel conductance micropipet as a new approach to the study of ionic crystal dissolution kinetics
A new approach to the study of ionic crystal dissolution kinetics is described, based on the use of a dual-barrel theta conductance micropipet. The solution in the pipet is undersaturated with respect to the crystal of interest, and when the meniscus at the end of the micropipet makes contact with a selected region of the crystal surface, dissolution occurs causing the solution composition to change. This is observed, with better than 1 ms time resolution, as a change in the ion conductance current, measured across a potential bias between an electrode in each barrel of the pipet. Key attributes of this new technique are: (i) dissolution can be targeted at a single crystal surface; (ii) multiple measurements can be made quickly and easily by moving the pipet to a new location on the surface; (iii) materials with a wide range of kinetics and solubilities are open to study because the duration of dissolution is controlled by the meniscus contact time; (iv) fast kinetics are readily amenable to study because of the intrinsically high mass transport rates within tapered micropipets; (v) the experimental geometry is well-defined, permitting finite element method modeling to allow quantitative analysis of experimental data. Herein, we study the dissolution of NaCl as an example system, with dissolution induced for just a few milliseconds, and estimate a first-order heterogeneous rate constant of 7.5 (±2.5) × 10–5 cm s–1 (equivalent surface dissolution flux ca. 0.5 μmol cm–2 s–1 into a completely undersaturated solution). Ionic crystals form a huge class of materials whose dissolution properties are of considerable interest, and we thus anticipate that this new localized microscale surface approach will have considerable applicability in the future
Safeguarding the future of genomic research in South Africa: Broad consent and the protection of Personal Information Act No. 4 of 2013
Genomic research has been identified in South Africa (SA) as important in developing a strong bio-economy that has the potential to improve human health, drive job creation and offer potential solutions to the disease burden harboured by low- and middle-income countries. Central to the success of genomic research is the wide sharing of biological samples and data, but the true value of data can only be unlocked if there are laws and policies in place that foster the legal and ethical sharing of genomic data. The introduction and entry into force of SA's Protection of Personal Information Act (POPIA) No. 4 of 2013 is to be welcomed, but the wording of POPIA as it pertains to consent for the processing of personal information for research purposes has sparked a debate about the legal status of broad consent. We argue that a purposive interpretation of the legislation would permit broad consent for the processing of personal information for research. Although there are ongoing debates surrounding the ethical use of broad consent in Africa, the objective of this article is not to engage with the ethics of broad consent itself, but rather to focus on the legal status of broad consent for genomic data sharing under POPIA
Tn-Seq reveals hidden complexity in the utilization of host-derived glutathione in \u3cem\u3eFrancisella tularensis\u3c/em\u3e
Host-derived glutathione (GSH) is an essential source of cysteine for the intracellular pathogen Francisella tularensis. In a comprehensive transposon insertion sequencing screen, we identified several F. tularensis genes that play central and previously unappreciated roles in the utilization of GSH during the growth of the bacterium in macrophages. We show that one of these, a gene we named dptA, encodes a proton-dependent oligopeptide transporter that enables growth of the organism on the dipeptide Cys-Gly, a key breakdown product of GSH generated by the enzyme γ-glutamyltranspeptidase (GGT). Although GGT was thought to be the principal enzyme involved in GSH breakdown in F. tularensis, our screen identified a second enzyme, referred to as ChaC, that is also involved in the utilization of exogenous GSH. However, unlike GGT and DptA, we show that the importance of ChaC in supporting intramacrophage growth extends beyond cysteine acquisition. Taken together, our findings provide a compendium of F. tularensis genes required for intracellular growth and identify new players in the metabolism of GSH that could be attractive targets for therapeutic intervention
- …