327 research outputs found

    Effectiveness of Clery Act Timely Warnings and Emergency Notifications

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    The Clery Act (20 USC. § 1092(f)) is a federal law intended to improve campus safety by making information about crime as well as safety and security policies more accessible. Research has shown that the law’s requirements to collect crime statistics and publish annual security reports have limited impact. Little research has examined the effectiveness of the timely warning and emergency notification provisions. This study explored the perceptions of Campus Security Authorities (CSAs) to determine whether timely warning and emergency notification messages are an effective tool for improving campus safety; to what degree they result in unintended harmful effects; and whether current training of CSAs is adequate to develop CSAs’ knowledge and skills related to writing Clery Act message content. A 28-item questionnaire was distributed to a random sample of 5,000 individuals from a national list provided by the Clery Center. The completion rate was 10% (n=514) and the margin of error was +/-5% at the 95% confidence level. The results indicate that CSA’s perceive Clery Act messages to be effective at informing campus communities about crime, influencing safety-related behavior, prompting tips that solve crimes, and deterring crime. However, CSAs also indicated sizeable unintended harmful effects including that messages mislead people to believe that campuses are less safe than they actually are, provoke panic, reinforce racial stereotypes, are victim blaming, expose the identity of victims who report crime, trigger retaliation, re-traumatize victims of past crime, and cause chilling effects on crime reporting. Most CSAs (97%) receive training. However, only 44% reported receiving training that covered best practices for drafting messages that are trauma-informed regarding victims of sexual violence and only 33% reported receiving training that covered best practices for handling information about the race of suspects in crime reports

    Efficacy of Clery Act Timely Warning and Emergency Notification Messages

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    The Clery Act (20 U.S.C. § 1092(f)) was passed following the rape and murder of Jeanne Clery in 1986 at Lehigh University. The intent of the law was to improve campus safety by making information about crime as well as safety and security policies more accessible to students, parents, employees, and others. This study explored the efficacy of the emergency notification and timely warnings provisions of the law. The study found these messages to be useful in promoting campus safety, particularly by informing people about safety issues and impacting people’s behavior related to self-protection. However, safety related behavior changes are perceived to be short-term rather than long-term. Problems were also reported in relation to timeliness of messages, message content and the unintended impacts or consequences that messages can have. Unintended impacts or consequences include the potential for messages to lead to perceptions that a campus is an unsafe campus environment when in fact risks are small; to reinforce racial stereotypes; to be perceived as victim blaming, or revealing information that causes victims who report crime to be outed; or trigger psychological complications. The potential for these issues to cause a “chilling effect” or impede law enforcement efforts were also reported

    Automated Isolation of Translational Efficiency Bias that Resists the Confounding Effect of GC(AT)-Content

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    Genomic sequencing projects are an abundant source of information for biological studies ranging from the molecular to the ecological in scale; however, much of the information present may yet be hidden from casual analysis. One such information domain, trends in codon usage, can provide a wealth of information about an organism\u27s genes and their expression. Degeneracy in the genetic code allows more than one triplet codon to code for the same amino acid, and usage of these codons is often biased such that one or more of these synonymous codons is preferred. Detection of this bias is an important tool in the analysis of genomic data, particularly as a predictor of gene expressivity. Methods for identifying codon usage bias in genomic data that rely solely on genomic sequence data are susceptible to being confounded by the presence of several factors simultaneously influencing codon selection. Presented here is a new technique for removing the effects of one of the more common confounding factors, GC(AT)-content, and of visualizing the search-space for codon usage bias through the use of a solution landscape. This technique successfully isolates expressivity-related codon usage trends, using only genomic sequence information, where other techniques fail due to the presence of GC(AT)-content confounding influences

    Genetic loci regulating cadmium content in rice grains

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    Open Access via the Springer Compact Agreement Acknowledgements: Plant material was imported into the UK under import licence IMP/SOIL/19/2014. The authors would like to thank reviewers of the manuscript who helped improve the presentation. Funding: The bulk of this work was supported by the Biotechnology and Biological Sciences Research Council, mostly from project BB/J003336/1. A small part of the work by AJT was supported by project BB/N013492/1 (NEWS-India-UK). PR was financially supported by a Royal Thai Government Scholarship and National Science and Technology Development Agency (NSTDA), Thailand and AAA supported by the Elphinstone Scholarship Scheme (University of Aberdeen).Peer reviewedPublisher PD

    Thermodynamic parameters of bonds in glassy materials from viscosity-temperature relationships

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    Doremus's model of viscosity assumes that viscous flow in amorphous materials is mediated by broken bonds (configurons). The resulting equation contains four coefficients, which are directly related to the entropies and enthalpies of formation and motion of the configurons. Thus by fitting this viscosity equation to experimental viscosity data these enthalpy and entropy terms can be obtained. The non-linear nature of the equation obtained means that the fitting process is non-trivial. A genetic algorithm based approach has been developed to fit the equation to experimental viscosity data for a number of glassy materials, including SiO2, GeO2, B2O3, anorthite, diopside, xNa2O–(1-x)SiO2, xPbO–(1-x)SiO2, soda-lime-silica glasses, salol, and α-phenyl-o-cresol. Excellent fits of the equation to the viscosity data were obtained over the entire temperature range. The fitting parameters were used to quantitatively determine the enthalpies and entropies of formation and motion of configurons in the analysed systems and the activation energies for flow at high and low temperatures as well as fragility ratios using the Doremus criterion for fragility. A direct anti-correlation between fragility ratio and configuron percolation threshold, which determines the glass transition temperature in the analysed materials, was found

    Winter and spring controls on the summer food web of the coastal West Antarctic Peninsula

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    Understanding the mechanisms by which climate variability affects multiple trophic levels in food webs is essential for determining ecosystem responses to climate change. Here we use over two decades of data collected by the Palmer Long Term Ecological Research program (PAL-LTER) to determine how large-scale climate and local physical forcing affect phytoplankton, zooplankton and an apex predator along the West Antarctic Peninsula (WAP). We show that positive anomalies in chlorophyll-a (chl-a) at Palmer Station, occurring every 4-6 years, are constrained by physical processes in the preceding winter/spring and a negative phase of the Southern Annular Mode (SAM). Favorable conditions for phytoplankton included increased winter ice extent and duration, reduced spring/summer winds, and increased water column stability via enhanced salinity-driven density gradients. Years of positive chl-a anomalies are associated with the initiation of a robust krill cohort the following summer, which is evident in Adelie penguin diets, thus demonstrating tight trophic coupling. Projected climate change in this region may have a significant, negative impact on phytoplankton biomass, krill recruitment and upper trophic level predators in this coastal Antarctic ecosystem

    Safety and Feasibility of Minimally Invasive Inguinal Lymph Node Dissection in Patients With Melanoma (SAFE-MILND): Report of a Prospective Multi-institutional Trial.

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    BACKGROUND: Minimally invasive inguinal lymph node dissection (MILND) is a novel approach to inguinal lymphadenectomy. SAFE-MILND (NCT01500304) is a multicenter, phase I/II clinical trial evaluating the safety and feasibility of MILND for patients with melanoma in a group of surgeons newly adopting the procedure. METHODS: Twelve melanoma surgeons from 10 institutions without any previous MILND experience, enrolled patients into a prospective study after completing specialized training including didactic lectures, participating in a hands-on cadaveric laboratory, and being provided an instructional DVD of the procedure. Complications and adverse postoperative events were graded using the National Cancer Institute (NCI) Common Terminology Criteria for Adverse Events Version 4.0. RESULTS: Eighty-seven patients underwent a MILND. Seventy-seven cases (88.5%) were completed via a minimally invasive approach. The median total inguinal lymph nodes pathologically examined (SLN + MILND) was 12.0 (interquartile range 8.0, 14.0). Overall, 71% of patients suffered an adverse event (AE); the majority of these were grades 1 and 2, with 26% of patients experiencing a grade 3 AE. No grade 4 or 5 AEs were observed. CONCLUSIONS: After a structured training program, high-volume melanoma surgeons adopted a novel surgical technique with a lymph node retrieval rate that met or exceeded current oncologic guidelines and published benchmarks, and a favorable morbidity profile

    Constraints to Implementing the Essential Health Package in Malawi

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    Increasingly seen as a useful tool of health policy, Essential or Minimal Health Packages direct resources to interventions that aim to address the local burden of disease and be cost-effective. Less attention has been paid to the delivery mechanisms for such interventions. This study aimed to assess the degree to which the Essential Health Package (EHP) in Malawi was available to its population and what health system constraints impeded its full implementation. The first phase of this study comprised a survey of all facilities in three districts including interviews with all managers and clinical staff. In the second and third phase, results were discussed with District Health Management Teams and national level stakeholders, respectively, including representatives of the Ministry of Health, Central Medical Stores, donors and NGOs. The EHP in Malawi is focussing on the local burden of disease; however, key constraints to its successful implementation included a widespread shortage of staff due to vacancies but also caused by frequent trainings and meetings (only 48% of expected man days of clinical staff were available; training and meetings represented 57% of all absences in health centres). Despite the training, the percentage of health workers aware of vital diagnostic and therapeutic approaches to EHP conditions was weak. Another major constraint was shortages of vital drugs at all levels of facilities (e.g. Cotrimoxazole was sufficiently available to treat the average number of patients in only 27% of health centres). Although a few health workers noted some improvement in infrastructure and working conditions, they still considered them to be widely inadequate. In Malawi, as in similar resource poor countries, greater attention needs to be given to the health system constraints to delivering health care. Removal of these constraints should receive priority over the considerable focus on the development and implementation of essential packages of interventions
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