Induced earthquake families reveal distinctive evolutionary patterns near disposal wells

The timing of events in seismic sequences can provide insights into the physical processes controlling fault slip. In southern Kansas, the rate of earthquakes rose rapidly starting in 2013 following expansion of energy production into the area, demanding the disposal of large volumes of wastewater into deep wells. Seismicity catalogs that are complete to low magnitudes can provide insights into the physical processes that induce seismicity near wastewater disposal. We develop a catalog of over 130,000 earthquakes recorded in southern Kansas from mid‐March 2014 through December 2017 by applying a matched filter algorithm to an original catalog of 5,831 template earthquakes. Detections have nearly identical waveforms to their associated template event and represent slip on nearly co‐located sections of a fault. We select template events with at least 100 associated detections and examine the characteristics of these prolific families of earthquakes. We find that families located close (<10 km) to areas with significant volumes of injected fluids have near‐Poissonian interevent times and the families remain active over longer durations. Families farther from high‐volume injection wells show strong clustering of interevent times and shorter sequence durations. We conclude that increasing pore fluid pressures from nearby disposal of large volumes of wastewater is the primary driver of these long duration episodes, with earthquake‐earthquake interactions driving sequences at greater distance from the wells

PROGRAM & PROCEEDINGS of the 2022 COLLOQUIUM OF THE STONY BROOK UNIVERSITY INTELLECTUAL PROPERTY PARTNERS Female Perspectives on Entrepreneurship and Research How diverse perspectives inspire creativity, drive innovation, and encourage inclusive economic growth

Diverse and varied perspectives are not only central to our institutional mission, but are essential to our society, as we hope to create a more inclusive, more sustainable and ultimately brighter world. Diverse perspectives and collaboration between different institutions, fields and industries must become the norm. This is the program and proceeding of Stony Brook University\u27s colloquium on female perspectives on entrepreneurship and research and how diverse perspectives inspire creativity, drive innovation, and encourage inclusive economic growth. This was a much-needed discussion in January 2022 that\u27s important for the development of entrepreneurship and research worldwide. At Stony Brook University, the entire research community believes that creating an equitable and integrated work environment is an essential part of the success of its innovation and culture. So, this proceeding provides a transcript of the meaningful moderated discussion between 6 expert panelists about female entrepreneurship and research

Female Perspectives on Entrepreneurship and Research How diverse perspectives inspire creativity, drive innovation, and encourage inclusive economic growth

Diverse and varied perspectives are not only central to our institutional mission, but are essential to our society, as we hope to create a more inclusive, more sustainable and ultimately brighter world. Diverse perspectives and collaboration between different institutions, fields and industries must become the norm. This is the program and proceeding of Stony Brook University\u27s colloquium on female perspectives on entrepreneurship and research and how diverse perspectives inspire creativity, drive innovation, and encourage inclusive economic growth. This was a much-needed discussion in January 2022 that\u27s important for the development of entrepreneurship and research worldwide. At Stony Brook University, the entire research community believes that creating an equitable and integrated work environment is an essential part of the success of its innovation and culture. So, this proceeding provides a transcript of the meaningful moderated discussion between 6 expert panelists about female entrepreneurship and research

Female Perspectives on Entrepreneurship and Research How diverse perspectives inspire creativity, drive innovation, and encourage inclusive economic growth

Diverse and varied perspectives are not only central to our institutional mission, but are essential to our society, as we hope to create a more inclusive, more sustainable and ultimately brighter world. Diverse perspectives and collaboration between different institutions, fields and industries must become the norm. This is the program and proceeding of Stony Brook University\u27s colloquium on female perspectives on entrepreneurship and research and how diverse perspectives inspire creativity, drive innovation, and encourage inclusive economic growth. This was a much-needed discussion in January 2022 that\u27s important for the development of entrepreneurship and research worldwide. At Stony Brook University, the entire research community believes that creating an equitable and integrated work environment is an essential part of the success of its innovation and culture. So, this proceeding provides a transcript of the meaningful moderated discussion between 6 expert panelists about female entrepreneurship and research

Uncovering Shakespeare\u27s Sisters in Special Collections and College Archives, Musselman Library

Foreword by Professor Suzanne J. Flynn I have taught the first-year seminar, Shakespeare’s Sisters, several times, and over the years I have brought the seminar’s students to the Folger Shakespeare Library in Washington, D.C. There, the wonderful librarians have treated the students to a special exhibit of early women’s manuscripts and first editions, beginning with letters written by Elizabeth I and proceeding through important works by seventeen and eighteenth-century women authors such as Aemelia Lanyer, Anne Finch, Aphra Behn, and Mary Wollstonecraft. This year I worked with Carolyn Sautter, the Director of Special Collections and College Archives, to give my 2018 seminar students the opportunity to produce a sequel to the Folger exhibit of early modern women writers. Special Collections houses an impressive array of first editions from the nineteenth and twentieth centuries, many of them acquired from Thomas Y. Cooper, the former editor of the Hanover Evening Sun newspaper, who donated over 1600 items to Musselman Library in 1965. Working with Kerri Odess-Harnish, we chose first editions of eight significant works of literature written by American and British women from the mid-nineteenth through the mid-twentieth centuries. The students worked in pairs, researching a single book and producing a report that outlines important biographical facts about the author, the book’s publication and reception history, and finally the significance of the book in the years since its publication. We hope that our project will draw attention to the wealth of literary treasures housed in Special Collections at Musselman Library, but especially to these works by eight of “Shakespeare’s Sisters.

Induced earthquake families reveal distinctive evolutionary patterns near disposal wells

The timing of events in seismic sequences can provide insights into the physical processes controlling fault slip. In southern Kansas, the rate of earthquakes rose rapidly starting in 2013 following expansion of energy production into the area, demanding the disposal of large volumes of wastewater into deep wells. Seismicity catalogs that are complete to low magnitudes can provide insights into the physical processes that induce seismicity near wastewater disposal. We develop a catalog of over 130,000 earthquakes recorded in southern Kansas from mid‐March 2014 through December 2017 by applying a matched filter algorithm to an original catalog of 5,831 template earthquakes. Detections have nearly identical waveforms to their associated template event and represent slip on nearly co‐located sections of a fault. We select template events with at least 100 associated detections and examine the characteristics of these prolific families of earthquakes. We find that families located close (<10 km) to areas with significant volumes of injected fluids have near‐Poissonian interevent times and the families remain active over longer durations. Families farther from high‐volume injection wells show strong clustering of interevent times and shorter sequence durations. We conclude that increasing pore fluid pressures from nearby disposal of large volumes of wastewater is the primary driver of these long duration episodes, with earthquake‐earthquake interactions driving sequences at greater distance from the wells

Bridging Alone: Religious Conservatism, Marital Homogamy, and Voluntary Association Membership

This study characterizes social insularity of religiously conservative American married couples by examining patterns of voluntary associationmembership. Constructing a dataset of 3938 marital dyads from the second wave of the National Survey of Families and Households, the author investigates whether conservative religious homogamy encourages membership in religious voluntary groups and discourages membership in secular voluntary groups. Results indicate that couples’ shared affiliation with conservative denominations, paired with beliefs in biblical authority and inerrancy, increases the likelihood of religious group membership for husbands and wives and reduces the likelihood of secular group membership for wives, but not for husbands. The social insularity of conservative religious groups appears to be reinforced by homogamy—particularly by wives who share faith with husbands

The transmembrane serine protease (TMPRSS3) mutated in deafness DFNB8/10 activates the epithelial sodium channel (ENaC) in vitro

TMPRSS3 encodes a transmembrane serine protease that contains both LDLRA and SRCR domains and is mutated in non-syndromic autosomal recessive deafness (DFNB8/10). To study its function, we cloned the mouse ortholog which maps to Mmu17, which is structurally similar to the human gene and encodes a polypeptide with 88% identity to the human protein. RT-PCR and RNA in situ hybridization on rat and mouse cochlea revealed that Tmprss3 is expressed in the spiral ganglion, the cells supporting the organ of Corti and the stria vascularis. RT-PCR on mouse tissues showed expression in the thymus, stomach, testis and E19 embryos. Transient expression of wild-type or tagged TMPRSS3 protein showed a primary localization in the endoplasmic reticulum. The epithelial amiloride-sensitive sodium channel (ENaC), which is expressed in many sodium-reabsorbing tissues including the inner ear and is regulated by membrane-bound channel activating serine proteases (CAPs), is a potential substrate of TMPRSS3. In the Xenopus oocyte expression system, proteolytic processing of TMPRSS3 was associated with increased ENaC mediated currents. In contrast, 6 TMPRSS3 mutants (D103G, R109W, C194F, W251C, P404L, C407R) causing deafness and a mutant in the catalytic triad of TMPRSS3 (S401A), failed to undergo proteolytic cleavage and activate ENaC. These data indicate that important signaling pathways in the inner ear are controlled by proteolytic cleavage and suggest: (i) the existence of an auto-catalytic processing by which TMPRSS3 would become active, and (ii) that ENaC could be a substrate of TMPRSS3 in the inner ea

Improving treatment plan evaluation with automation

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/135377/1/acm20016.pd

The dopamine D2 receptor gene and depressive and anxious symptoms in childhood: Associations and evidence for gene-environment correlation and gene-environment interaction

ObjectiveS: Research implicates the A1 allele of the dopamine D2 receptor gene (DRD2) Taq1A polymorphism in the development of depression and anxiety. Furthermore, recent papers suggest that children with A1 allele of this gene may receive less positive parenting, and that the effects of this gene on child symptoms may be moderated by parenting. We sought to replicate and extend these findings using behavioral measures in a nonclinical sample of young children. Methods: In a sample of 473 preschool-aged children and their mothers, structured clinical interview measures and maternal reports of child symptoms were collected, and standardized observations of parent-child interactions were conducted. Results: An association was detected between the DRD2 A1 allele and symptoms of depression and anxiety indexed using interview and parent report methods. As found in previous reports, children with the DRD2 A1 allele received less supportive parenting and displayed higher levels of negative emotionality during parent-child interactions. Tests of mediation and moderation were conducted. Conclusion: We found associations between the DRD2 A1 allele and early-emerging anxious and depressive symptoms in a community sample of preschool-aged children, and evidence of a gene-environment correlation and moderation of the main effect of child genotype on child symptoms by parenting. © 2010 Wolters Kluwer Health | Lippincott Williams & Wilkins