The relationship between microscales and wind-wave spectral development

Submitted in partial fulfillment of the requirements for the degree of Doctor of Philosophy at the Massachusetts Institute of Technology and the Woods Hole Oceanographic Institution October, 1971The objective of this study was to describe the mechanics of wind wave generation and spectral development. Intermittency, high frequency microstructure in wind and wave fields, and strong nonlinear coupling involving a wide range of scales are shown to be crucial elements in the transfer of momentum to, from, and within the wave field. None of these elements are included in available theories. Measurements of wave height and of the turbulent atmospheric and subsurface boundary layers were made, from a small surface following platform and from a stable 38.5m spar buoy. The structure of moving gust patterns (cat's paws) is described and related to the generation of surface waves. Results from this and other background studies are then applied to a discussion of spectral growth during a two day period of active wave generation. Cat's paws contain 'bursts' of intense turbulent stress and buoyancy fluctuations separated by quiescent 'intervals'. There is a difference of over three orders of magnitude in fluctuation strength between these features. Rapid growth rate generation of high frequency surface waves and atmospheric turbulence occurs during the bursts. The resultant microscale components aid the growth of lower frequency instabilities by strong nonlinear coupling between scales of motion and by acting as drag or roughness elements. Evidence of strong coupling between frequency bands and of weakly resonant capillary-gravity wave interactions is presented. Thermal stratification has a strong influence on fluctuation magnitude and can delay the onset of surface wave generation. Major spectral growth is highly unsteady. Much of the momentum flux from air to sea occurs during intermittent events that are similar in nature to cat's paws, and goes directly into high frequency waves. The bursts occur predominantly over large groups of surface waves and involve strong nonlinear interactions between media and frequency bands. The long-term equilibrium balance between wind and water is disrupted by variations in surface currents. There are 'critical' wind speeds characterized by anomalous relationships between parameters of the predominantly logarithmic velocity profile

Peculiar Multimodality on the Horizontal Branch of the Globular Cluster NGC 2808

We present distributions of colors of stars along the horizontal branch of the globular cluster NGC 2808, from Hubble Space Telescope WFPC2 imaging in B, V, and an ultraviolet filter (F218W). This cluster's HB is already known to be strongly bimodal, with approximately equal-sized HB populations widely separated in the color-magnitude diagram. Our images reveal a long blue tail with two gaps, for a total of four nearly distinct HB groups. These gaps are very narrow, corresponding to envelope-mass differences of only \sim 0.01 Msun. This remarkable multimodality may be a signature of mass-loss processes, subtle composition variations, or dynamical effects; we briefly summarize the possibilities. The existence of narrow gaps between distinct clumps on the HB presents a challenge for models that attempt to explain HB bimodality or other peculiar HB structures.Comment: LaTeX, including compressed figures. To appear in ApJL. Larger (851k) PostScript version, including high-quality figures, available from http://astro.berkeley.edu/~csosin/pub

Discovery of Extended Blue Horizontal Branches in Two Metal-Rich Globular Clusters

We have used WFPC2 to construct B, V color-magnitude diagrams of four metal-rich globular clusters, NGC 104 (47 Tuc), NGC 5927, NGC 6388, and NGC 6441. All four clusters have well populated red horizontal branches (RHB), as expected for their metallicity. However, NGC 6388 and 6441 also exhibit a prominent blue HB (BHB) extension, including stars reaching as faint in V as the turnoff luminosity. This discovery demonstrates directly for the first time that a major population of hot HB stars can exist in old, metal-rich systems. This may have important implications for the interpretation of the integrated spectra of elliptical galaxies. The cause of the phenomenon remains uncertain. We examine the possibility that NGC 6388 and 6441 are older than the other clusters, but a simple difference in age may not be sufficient to produce the observed distributions along the HB. The high central densities in NGC 6388 and 6441 suggest that the existence of the blue HB (BHB) tails might be caused by stellar interactions in the dense cores of these clusters, which we calculate to have two of the highest collision rates among globular clusters in the Galaxy. Tidal collisions might act in various ways to enhance loss of envelope mass, and therefore populate the blue side of the HB. However, the relative frequency of tidal collisions does not seem large enough (compared to that of the clusters with pure RHBs) to account for such a drastic difference in HB morphology. While a combination of an age difference and dynamical interactions may help, prima facie the lack of a radial gradient in the BHB/RHB star ratio seems to argue against dynamical effects playing a role.Comment: LaTeX, includes one Postscript figure. To appear in ApJ

Humans and Insects Decide in Similar Ways

Behavioral ecologists assume that animals use a motivational mechanism for decisions such as action selection and time allocation, allowing the maximization of their fitness. They consider both the proximate and ultimate causes of behavior in order to understand this type of decision-making in animals. Experimental psychologists and neuroeconomists also study how agents make decisions but they consider the proximate causes of the behavior. In the case of patch-leaving, motivation-based decision-making remains simple speculation. In contrast to other animals, human beings can assess and evaluate their own motivation by an introspection process. It is then possible to study the declared motivation of humans during decision-making and discuss the mechanism used as well as its evolutionary significance. In this study, we combine both the proximate and ultimate causes of behavior for a better understanding of the human decision-making process. We show for the first time ever that human subjects use a motivational mechanism similar to small insects such as parasitoids [1] and bumblebees [2] to decide when to leave a patch. This result is relevant for behavioral ecologists as it supports the biological realism of this mechanism. Humans seem to use a motivational mechanism of decision making known to be adaptive to a heterogeneously distributed resource. As hypothesized by Hutchinson et al. [3] and Wilke and Todd [4], our results are consistent with the evolutionary shaping of decision making because hominoids were hunters and gatherers on food patches for more than two million years. We discuss the plausibility of a neural basis for the motivation mechanism highlighted here, bridging the gap between behavioral ecology and neuroeconomy. Thus, both the motivational mechanism observed here and the neuroeconomy findings are most likely adaptations that were selected for during ancestral times

SARS-CoV-2 Omicron is an immune escape variant with an altered cell entry pathway

Vaccines based on the spike protein of SARS-CoV-2 are a cornerstone of the public health response to COVID-19. The emergence of hypermutated, increasingly transmissible variants of concern (VOCs) threaten this strategy. Omicron (B.1.1.529), the fifth VOC to be described, harbours multiple amino acid mutations in spike, half of which lie within the receptor-binding domain. Here we demonstrate substantial evasion of neutralization by Omicron BA.1 and BA.2 variants in vitro using sera from individuals vaccinated with ChAdOx1, BNT162b2 and mRNA-1273. These data were mirrored by a substantial reduction in real-world vaccine effectiveness that was partially restored by booster vaccination. The Omicron variants BA.1 and BA.2 did not induce cell syncytia in vitro and favoured a TMPRSS2-independent endosomal entry pathway, these phenotypes mapping to distinct regions of the spike protein. Impaired cell fusion was determined by the receptor-binding domain, while endosomal entry mapped to the S2 domain. Such marked changes in antigenicity and replicative biology may underlie the rapid global spread and altered pathogenicity of the Omicron variant

Genomic epidemiology of SARS-CoV-2 in a UK university identifies dynamics of transmission

AbstractUnderstanding SARS-CoV-2 transmission in higher education settings is important to limit spread between students, and into at-risk populations. In this study, we sequenced 482 SARS-CoV-2 isolates from the University of Cambridge from 5 October to 6 December 2020. We perform a detailed phylogenetic comparison with 972 isolates from the surrounding community, complemented with epidemiological and contact tracing data, to determine transmission dynamics. We observe limited viral introductions into the university; the majority of student cases were linked to a single genetic cluster, likely following social gatherings at a venue outside the university. We identify considerable onward transmission associated with student accommodation and courses; this was effectively contained using local infection control measures and following a national lockdown. Transmission clusters were largely segregated within the university or the community. Our study highlights key determinants of SARS-CoV-2 transmission and effective interventions in a higher education setting that will inform public health policy during pandemics.</jats:p

Investigation of hospital discharge cases and SARS-CoV-2 introduction into Lothian care homes

Background The first epidemic wave of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) in Scotland resulted in high case numbers and mortality in care homes. In Lothian, over one-third of care homes reported an outbreak, while there was limited testing of hospital patients discharged to care homes. Aim To investigate patients discharged from hospitals as a source of SARS-CoV-2 introduction into care homes during the first epidemic wave. Methods A clinical review was performed for all patients discharges from hospitals to care homes from 1st March 2020 to 31st May 2020. Episodes were ruled out based on coronavirus disease 2019 (COVID-19) test history, clinical assessment at discharge, whole-genome sequencing (WGS) data and an infectious period of 14 days. Clinical samples were processed for WGS, and consensus genomes generated were used for analysis using Cluster Investigation and Virus Epidemiological Tool software. Patient timelines were obtained using electronic hospital records. Findings In total, 787 patients discharged from hospitals to care homes were identified. Of these, 776 (99%) were ruled out for subsequent introduction of SARS-CoV-2 into care homes. However, for 10 episodes, the results were inconclusive as there was low genomic diversity in consensus genomes or no sequencing data were available. Only one discharge episode had a genomic, time and location link to positive cases during hospital admission, leading to 10 positive cases in their care home. Conclusion The majority of patients discharged from hospitals were ruled out for introduction of SARS-CoV-2 into care homes, highlighting the importance of screening all new admissions when faced with a novel emerging virus and no available vaccine