Body structural and cellular aging of women with low socioeconomic status in Hungary: A pilot study.

OBJECTIVES: The health status of an individual is determined not only by their genetic background but also by their physical environment, social environment and access and use of the health care system. The Roma are one of the largest ethnic minority groups in Hungary. The majority of the Roma population live in poor conditions in segregated settlements in Hungary, with most experiencing higher exposure to environmental health hazards. The main aim of this study was to examine the biological health and aging status of Roma women living in low socioeconomic conditions in Hungary. METHODS: Low SES Roma (n: 20) and high SES non-Roma women (n: 30) aged between 35 and 65 years were enrolled to the present analysis. Body mass components were estimated by body impedance analysis, bone structure was estimated by quantitative ultrasound technique. Cellular aging was assessed by X chromosome loss estimation. Data on health status, lifestyle and socioeconomic factors were collected by questionnaires. RESULTS: The results revealed that low SES women are prone to be more obese, have a higher amount of abdominal body fat, and have worse bone structure than the national reference values. A positive relationship was found between aging and the rate of X chromosome loss was detected only in women with low SES. Waist to hip ratio, existence of cardiovascular diseases and the number of gravidities were predictors of the rate of X chromosome loss in women. CONCLUSIONS: The results suggested that age-adjusted rate of X chromosome loss could be related to the socioeconomic status

Sport Activity Load and Skeletomuscular Robustness in Elite Youth Athletes

In an earlier report, bone mineral reference values for young athletes were developed. This study addressed variations in bone mineral parameters of young athletes participating in sports with different mechanical loads. The bone mineral status of 1793 male and female athletes, 11 to 20 years of age, in several sports was measured with DEXA. Specific bone mineral parameters were converted to z-scores relative to age- and sex-specific reference values specified by the DEXA software. Z-score profiles and principal components analyses were used to identify body structural components in the young athletes and to evaluate the associations between the identified component and type of sport defined by mechanical load. A unique skeletomuscular robusticity of male wrestlers, pentathletes, and cyclists was noted: wrestlers had significantly more developed skeletomuscular robusticity and bone mineral density compared to the age-group average among elite athletes, while pentathletes and cyclists had lower bone mineral parameters than the age-group references among elite athletes. Among female athletes, bone mineral parameters of both the trunk and extremities of rhythmic gymnasts and pentathletes were significantly lower compared to the age-group means for elite athletes. The bone mineral development of elite young athletes varies with the impact forces associated with their respective sports. The skeletal development of cyclists, pentathletes, and rhythmic gymnasts should be monitored regularly as their bone development lags behind that of their athlete peers and the reference for the general population

The Oral Microbiome Profile of Water Polo Players Aged 16–20

Objectives: Chlorine has a strong antibacterial property and is the disinfectant most frequently used in swimming pools. Therefore, the microbiota community in the oral cavity of those who practice water sports is assumed to be special due to their regular immersion in water. Adverse changes in the composition of oral cavity microbiota may have serious health consequences. We aimed to compare the oral microbiome between water polo players and non-athletes. We hypothesized that the oral cavity microbiota community differed between water polo players and non-athletes. Materials and Methods: Altogether, 124 water polo players (62 males and 62 females, aged between 9 and 20 years) and 16 non-athlete youths (control group, eight males and eight females, aged between 16 and 20 years, mean age + SD = 17.1 + 1.4 years) who participated in body structure examinations voluntarily agreed to participate in the study. In a randomly selected subsample of water polo players (n: 29, aged between 16 and 20 years, mean age + SD = 17.3 + 1.0 years), saliva samples were also collected. Saliva samples were collected from all non-athlete youths (n: 16, aged between 16 and 20 years). The oral microbiome was determined from a saliva sample, and DNA was isolated using the QIAmp DNA Blood Mini Kit. The 16S rRNA gene amplicon sequencing method was used to analyze the microbiome community. PCR primers were trimmed from the sequence reads with Cutadapt. R library DADA2 was used to process reads in the abundance analysis. Results: In general, Streptococcus, Veilonella, and Prevotella genera constituted more than 50% of the oral microbiome community in the two participant groups combined (n = 45). The oral microbial profile had significant sexual dimorphism and differed between water polo players and the non-athletes. Compared to females, males had a higher (p Atopobium (medium effect size) and Pravotella_7 (very large effect size) genera and a lower (p Fusobacterium (large effect size), Gemella (large effect size), and Streptococcus (large effect size) genera. Compared to non-athletes, water polo players had higher (p Veillonella and lower (p < 0.05, large effect size) relative abundance of the genus Gemella. Conclusions: The results suggest that regular water training can unfavorably alter the composition of the oral microbial community