Effects of cinnamon supplementation on antioxidant status and serum lipids in women with polycystic ovary syndrome

Background The objectives of study were to investigate the effects of cinnamon supplementation on antioxidant status and serum lipids in women with polycystic ovary syndrome (PCOS). Methods This double-blind randomized controlled clinical trial was conducted on 84 overweight or obese PCOS patients; aged 20�38 years. Subjects in cinnamon (n = 42) and placebo (n = 42) groups were given 3 cinnamon capsules (each one contained 500 mg cinnamon) or placebo daily for 8 weeks. Fasting blood samples, anthropometric measurements and dietary intake data were gathered at the beginning and at the end of the study. Independent t test, paired t test and analysis of covariance were used to analyze of data. Results Cinnamon significantly increased serum total antioxidant capacity (P = 0.005). Malondialdehyde was significantly decreased compared with placebo (P = 0.014). Cinnamon supplementation significantly improved serum level of total cholesterol, low-density lipoprotein cholesterol and high-density lipoprotein cholesterol (all P < 0.05). No significant effect was detected on serum triglyceride level. Conclusions Cinnamon supplementation improved antioxidant status and serum lipid profile in women with PCOS and may be applicable for reducing PCOS risk factors. © 2017 Center for Food and Biomolecules, National Taiwan Universit

Effects of cinnamon supplementation on antioxidant status and serum lipids in women with polycystic ovary syndrome

Background The objectives of study were to investigate the effects of cinnamon supplementation on antioxidant status and serum lipids in women with polycystic ovary syndrome (PCOS). Methods This double-blind randomized controlled clinical trial was conducted on 84 overweight or obese PCOS patients; aged 20�38 years. Subjects in cinnamon (n = 42) and placebo (n = 42) groups were given 3 cinnamon capsules (each one contained 500 mg cinnamon) or placebo daily for 8 weeks. Fasting blood samples, anthropometric measurements and dietary intake data were gathered at the beginning and at the end of the study. Independent t test, paired t test and analysis of covariance were used to analyze of data. Results Cinnamon significantly increased serum total antioxidant capacity (P = 0.005). Malondialdehyde was significantly decreased compared with placebo (P = 0.014). Cinnamon supplementation significantly improved serum level of total cholesterol, low-density lipoprotein cholesterol and high-density lipoprotein cholesterol (all P < 0.05). No significant effect was detected on serum triglyceride level. Conclusions Cinnamon supplementation improved antioxidant status and serum lipid profile in women with PCOS and may be applicable for reducing PCOS risk factors. © 2017 Center for Food and Biomolecules, National Taiwan Universit

Food Pattern and Anthropometric Indices of Students in Kerman University of Medical Sciences in 2009

Abstract: Introduction: It is estimated that by 2020, non communicable diseases will account for approximately two-third of all diseases that are often related to life style and nutrition. This study was conducted to assess Food pattern and anthropometric indices of students in Kerman University of Medical Sciences. Methods: In this cross-sectional study, 375 students (225 females, 150 males) with mean age of 20±2. 5 years were selected by multistage cluster sampling method. Food pattern was determined using 24-hour dietary recall questionnaire. Daily intake of energy and macronutrients, fiber and cholesterol were extracted by using nutritional software N4 and compared with, DRI (Dietary Reference Intake) and RDA (Recommended Dietary Allowances). Weight, height, waist and hip circumferences were measured by standard instruments and methods and BMI and WHR were determined accordingly. Data analysis was performed using t-test and Pearson correlation coefficient. Results: Mean daily intake of energy (Kcal), fat, Carbohydrate, protein (g), cholesterol (mg) and fiber (g) were respectively 2071±584, 84±29, 268±80, 69±22, 245±126 and 16±6.8 in females and 2774±638, 108±27, 361±95.5, 97±25.5, 367±185 and 19± 6.3 in males. Mean daily intake of cholesterol in males was higher than the recommended amount. Mean daily intake of fiber was lower than adequate intake in both groups. The percentage of energy intake from fat sources was higher than the favorite amount in both groups. Mean BMI (Kg/m2) and WHR were respectively 21.6±3.1 and 0.76±0.05 in females and 22.1±4.3 and 0.82±0.05 in males. A significant correlation was found between daily energy intake and WHR (r=0. 25 and P=0. 000). Conclusion: The daily diet composition of studied students is not balanced. Decrease of fat and increase of fiber consumption in both groups and reducing cholesterol intake in males for a balanced diet composition are recommended. Keywords: Food habit, Anthropometry, Questionnaires, Student

Prevalence of household food insecurity among people living with HIV/AIDS (Kerman- the southeast of Iran)

Background: Household food insecurity is one of the major public health issues that may affect an individual�s nutritional state, especially in patients with chronic diseases. The aim of this study was to evaluate the prevalence of household food insecurity and its association with sociodemographic and clinical factors among patients with HIV/AIDS in Kerman province, Iran. Methods: A cross sectional study was performed among the 179 patients with HIV/AIDS in Kerman province. Participants completed a questionnaire focusing on personal information, health, and clinical status. Also, household food security status was evaluated by the USDA (US Department of Agriculture) questionnaire. Data were analyzed using SPSS (Version 22) by descriptive, univariate, and multivariate logistic regression. P<0.05 was considered statistically significant. Results: Overall, 98 responding men and women were classified as household food secure (n=41; 40.8) and household food insecure (n=58; 59.2). Among the household food insecure patients, 14 (n=8) experienced lower household food insecurity, 38 (n=22) moderate household food insecurity, and 48 (n=28) severe household food insecurity. No significant differences were observed between household food secure and insecure groups in demographic variables. In clinical variables, only BMI index was significantly different between the two groups (p=0.040), but CD4 count was not significant between groups (p=0.220). Conclusion: Prevalence of household food insecurity was high among people living with HIV/AIDS in Kerman. It seems clinical variables such as BMI index, which indicates the nutritional status of individuals, affect household food security status among people living with HIV/AIDS. © 2021. Iran University of Medical Science

APOA II genotypes frequency and their interaction with saturated fatty acids consumption on lipid profile of patients with type 2 diabetes

BACKGROUND & AIM: Several studies have suggested that APOA II-265T/C polymorphism affect lipid profile. The aim of this study was to investigate the effect of -265T/C APOA II polymorphism and saturated fatty acids (SFA) intake interaction on lipid profile in diabetic population who are at risk for lipid disorders. METHODS: In this cross sectional study, 697 type 2 diabetic patients participated. Food consumption data were collected using validated semi-quantitative FFQ during the last year. Realtime-PCR was used to determine APOA II-265T/C genotypes. The interaction between the genotypes and SFA intake with lipid profile was tested using analysis of covariance (ANCOVA). RESULTS: According to APOA II-265T/C (rs5082) genotype distribution results, CC genotype with a frequency of 12.9% and TC with that of 47.7% showed the lowest and highest frequency in our population, respectively. CC genotype subjects had significantly lower total cholesterol, triglyceride, Cholesterol/HDL-c ratio and non-HDL cholesterol than T allele carriers (p = 0.009, p = 0.02, p = 0.02 and p = 0.002, respectively). The interaction between genotype and SFA intake contributed to significant higher levels of LDL-c and LDL/HDL in CCs (p = 0.05 and p = 0.01), suggesting vulnerability of these individuals to high intake of SFA in the diet. CONCLUSION: APOA II polymorphism may influence the saturated fatty acid intake required to prevent dyslipidemia in the type 2 diabetic population. Copyright © 2015 Elsevier Ltd and European Society for Clinical Nutrition and Metabolism. All rights reserved