Psykosocial arbetsmiljö : Finns det samband med kön, ålder, stress och KASAM

Tidigare forskning har visat att den psykosociala arbetsmiljön är en viktig del av arbetslivet eftersom individer påverkar och påverkas av den. En betydande del är också upplevelse av begriplighet, hanterbarhet och meningsfullhet som samtliga tillhör begreppet KASAM. Syftet med denna undersökning är att studera om olika aspekter kring psykosocial arbetsmiljö kan förklaras utifrån känsla av sammanhang (KASAM), kön, ålder och stress. Studien undersöker även samband mellan KASAM i kön, ålder samt stress. Undersökningen är fokuserad på både offentlig och privat sektor i arbetslivet n=140, fördelat på 94 kvinnor och 46 män. För att mäta den psykosociala arbetsmiljön används Rubenowitz instrument för psykosocial arbetsmiljökartläggning (PAK). Antonovskys instrument för känsla av sammanhang användes vid mätning av KASAM och The perceived stress scale (PSS) användes vid mätning av stress. Resultatet visar bland annat att män i åldersgruppen 41-60 är minst stressad samt känner mest egenkontroll i sitt arbetsliv och hög KASAM gör individer mindre stressade samt bidrar till bättre psykosocial arbetsmiljö. Studiens resultat diskuterades utifrån tidigare forskning.Previous research has shown that the psychosocial work environments is an important part of working life as individual affect and are affected by it. An important part is also experiencing comprehensibility, manageability and meaningfulness, which all belong to the concept SOC. The aim of this survey was to examine if various aspects of psychosocial work environment might be explained by Sense of Coherence (SOC), gender, age and stress. This study also examined whether there is a relationship between SOC and gender, age and stress. This survey is focused in both the public and private sectors work environment with n=140, distributed to 94 women and 46 men. To measure the psychosocial work environment Rubenowitz instrument for psychosocial work environment survey (PAK) was used. Antonovskys instrument for Sense of Coherence was used to measure SOC and the Perceived stress scale (PSS) was used to measure level of stress. The results show, among other findings, that men in the age category 41-60 are least stressed and feel more in control of their work. High level of SOC makes individuals less stressed and contributes to better psychosocial work environment. Study results were discussed based on previous research

Presence of terminal N-acetylgalactosamineβ1-4N-acetylglucosamine residues on O-linked oligosaccharides from gastric MUC5AC: Involvement in Helicobacter pylori colonization?

Isolation of MUC5AC mucins from the gastric mucosa from two secretor individuals (one from normal mucosa from a patient with gastric cancer and one from a control) showed different abilities to bind and induce the proliferation of the Helicobacter pylori strain J99. Analysis of the released O-linked oligosaccharides by LC-MS from these individuals showed a very heterogeneous mixture of species from the cancer patient containing both neutral and sialylated structures, whereas the normal sample showed dominating neutral blood group H terminating structures as well as neutral structures containing the di-N-acetyllactosamine (lacdiNAc) unit GalNAc beta 1-4GlcNAc beta 1- on the C-6 branch of the reducing end GalNAc. The linkage configuration of these epitopes were determined using C-4-specific fragmentation for the GalNAc beta 1-4GlcNAc beta 1- glycosidic linkage, comparison of the MS3 fragmentation with standards for linkage configuration and N-acetylhexosamine type as well as exoglycosidase treatment. It was also shown that the lacdiNAc epitope is present in both human and porcine gastric mucins, indicating that this is an epitope preserved between species. We hypothesize that the termination on gastric MUC5AC with lacdiNAc is in competition with complex glycosylation such as the Le(b) and H type 1 as well as complex sialylated structures. These are epitopes known to bind the H. pylori BabA and SabA adhesins