A cross-sectional study investigating the relationship between urinary albumin creatinine ratio and abdominal aortic calcification in adults

IntroductionThe presence of abdominal aortic calcification (AAC) is strongly linked to the development of atherosclerosis and the incidence of morbidity and mortality related to cardiovascular diseases (CVD). Urinary albumin creatinine ratio (UACR) was found related with the increased risk of CVD. The aim of this study is to explore the relationship between the UACR and severe AAC (SAAC).Methods and ResultsThis study included a total of 2,379 individuals aged over 40 years, and their information was obtained from the National Health and Nutrition Examination Survey conducted (NHANES) in 2013–2014. The measurement of AAC was conducted through dual-energy x-ray absorptiometry and assessed using the Kauppila scoring system. SAAC was characterized by a Kauppila score of 6 or higher. Multivariate regression models were used to analyze the relationship between UACR level and SAAC, with covariate adjustment. In the completely adapted model, the top third subgroup exhibits increased likelihood of SAAC (odds ratio 1.50; 95%CI: 0.98, 2.29; p = 0.030) in contrast to the bottom third subgroup. The subgroup analyses revealed a more pronounced correlation among the older participants (p-value for interaction = 0.013).DiscussionIn the United States, SAAC was more likely to occur in adults who had a higher probability of UACR. The use of UACR has the potential to be a valuable method for forecasting the likelihood of SAAC

Antibacterial activity of isopropoxy benzene guanidine against Riemerella anatipestifer

Introduction:Riemerella anatipestifer (R. anatipestifer) is an important pathogen in waterfowl, leading to substantial economic losses. In recent years, there has been a notable escalation in the drug resistance rate of R. anatipestifer. Consequently, there is an imperative need to expedite the development of novel antibacterial medications to effectively manage the infection caused by R. anatipestifer.Methods: This study investigated the in vitro and in vivo antibacterial activities of a novel substituted benzene guanidine analog, namely, isopropoxy benzene guanidine (IBG), against R. anatipestifer by using the microdilution method, time-killing curve, and a pericarditis model. The possible mechanisms of these activities were explored.Results and Discussion: The minimal inhibitory concentration (MIC) range of IBG for R. anatipestifer was 0.5–2 μg/mL. Time-killing curves showed a concentration-dependent antibacterial effect. IBG alone or in combination with gentamicin significantly reduced the bacterial load of R. anatipestifer in the pericarditis model. Serial-passage mutagenicity assays showed a low probability for developing IBG resistance. Mechanistic studies suggested that IBG induced membrane damage by binding to phosphatidylglycerol and cardiolipin, leading to an imbalance in membrane potential and the transmembrane proton gradient, as well as the decreased of intracellular adenosine triphosphate. In summary, IBG is a potential antibacterial for controlling R. anatipestifer infections

Hydrothermal Synthesis of CeO₂-SnO₂ Nanoflowers for Improving Triethylamine Gas Sensing Property

Developing the triethylamine sensor with excellent sensitivity and selectivity is important for detecting the triethylamine concentration change in the environment. In this work, flower-like CeO2-SnO2 composites with different contents of CeO2 were successfully synthesized by the one-step hydrothermal reaction. Some characterization methods were used to research the morphology and structure of the samples. Gas-sensing performance of the CeO2-SnO2 gas sensor was also studied and the results show that the flower-like CeO2-SnO2 composite showed an enhanced gas-sensing property to triethylamine compared to that of pure SnO2. The response value of the 5 wt.% CeO2 content composite based sensor to 200 ppm triethylamine under the optimum working temperature (310 °C) is approximately 3.8 times higher than pure SnO2. In addition, CeO2-SnO2 composite is also significantly more selective for triethylamine than pure SnO2 and has better linearity over a wide range of triethylamine concentrations. The improved gas-sensing mechanism of the composites toward triethylamine was also carefully discussed

Influences of risk-aversion behavior and purchasing option in a cross-border dual-channel supply chain

Considering the rapid development of cross-border e-commerce, this paper constructs a cross-border dual-channel supply chain with a supplier and a retailer in different countries. The supplier directly sells products to overseas market through an online channel and a retail channel. Since the supplier expands the overseas market and bears the potential risk of exchange rate volatility, the supplier is risk-averse. In the presence of exchange rate volatility, the risk-averse supplier decides whether to purchase an option to hedge against the risk of exchange rate volatility. Conditional value at risk is applied as a measure of the supplier's risk-averse behavior. To identify the conditions under which the risk-averse supplier should purchase an option, we analyze two scenarios: the benchmark model and the option model. By comparing the benchmark model with the option model, we show that if the option premium is lower than a threshold, the risk-averse supplier prefers to purchase an option, which also makes the retailer better off. Interestingly, when the supplier becomes less risk-averse, as the exchange rate volatility increases, both players benefit a higher utility in the option model. Finally, we verify the results’ robustness using numerical analysis

Study on the formation of direct reduced iron by using biomass as reductants of carbon containing pellets in RHF process

To investigate the possibility of using biomass reductants instead of fossil fuels in the formation of direct reduced iron (DRI) in rotary hearth furnace (RHF), three kinds of cheap biomass such as bamboo char, straw fiber and charcoal were selected as reductants to compare with anthracite and graphite. The effect of reductants, temperature, dwelling time, C/O ratio and particle sizes on the shrinkage, strength and metallization of the biomass/ore pellets was investigated and discussed. The optimized reduction conditions were obtained as 1200 degrees C, 20min, C/O = 0.7 and the particle size range of &lt;0.15 mm, 1-2 mm and 015-0.3 mm for straw fiber, bamboo char and charcoal respectively. The results showed that straw fiber was considered as an optimal reductant in the formation of direct reduced iron instead of fossil fuels. By the techniques of scanning electron microscope (SEM), thermogravimetric analysis (TGA), and X-ray diffraction (XRD), the mechanism of biomass as reductants was revealed. Volatile matter was confirmed to play an important role in the formation of DRI when biomass used as reductants. (C) 2017 Elsevier Ltd. All rights reserved.</p

Effects of Farmland Landscape Fragmentation on Agricultural Irrigation in Hotan Oasis

Farmland landscape fragmentation is an important problem affecting the agricultural modernization process in China. However, farmland landscape fragmentation leads to land being wasted and increases management costs, particularly in the dryland’s oasis regions. Therefore, investigating the impact of farmland landscape fragmentation on agricultural irrigation is of great significance in developing oasis agriculture. This paper used the landscape quantitative index (DIVISION), the moving window method, and gradient analysis methods to study the temporal and spatial pattern changes in farmland fragmentation in the Hotan Oasis. Additionally, the impact of fragmentation on irrigation in the oasis was elaborated upon by exploring the relationship between evapotranspiration and its components in farmland fragmentation. The results showed that the farmland area of the Hotan Oasis increased from 1546.19 km2 in 2000 to 2068.23 km2 in 2020, and farmland landscape fragmentation increased with the expansion of the Hotan Oasis. In addition, a significant relationship between farmland fragmentation and evapotranspiration and its components was evident. A lower DIVISION value corresponded to a higher ET value, a lower ETs/ETc ratio, and a higher water use efficiency. When the total farmland area is assumed to remain unchanged, the irrigation water consumption is reduced by 4.82 × 108 m3 according to the size and proportion of arable land with the lowest degree of fragmentation (L1, division value of 0.46). In addition, with the increase in the proportion of farmland, the scale of oasis decreases by 2431.56 km2 for the reduction in field roads, shelterbelt, and bare land. These findings suggest that solving the problem of farmland fragmentation can effectively reduce irrigation water consumption, realize the internal expansion of the oasis through intensive land use, and relieve the pressure of the external expansion of the oasis

Interaction Simulation of Vadose Zone Water and Groundwater in Cele Oasis: Assessment of the Impact of Agricultural Intensification, Northwestern China

Agricultural intensification has boosted land productivity, but it has also created new sustainability issues. As one of the most important human habitations and agricultural farming areas in arid areas, the Cele Oasis has a very developed agricultural system. This paper studies the long-term effects of different types of agricultural intensification strategies on groundwater level fluctuations in the Cele Oasis. A soil water flow (HYDRUS-1D) and aquifer simulation (MODFLOW) coupling model were used to construct the geometric structures of the vadose zone and saturated zone in the Cele Oasis and to analyze the recharge and discharge mechanism of the oasis. The results showed that HYDRUS-1D accurately simulated soil moisture transport in the Cele Oasis, providing reliable data for calibration of the MODFLOW model. The groundwater level simulated by MODFLOW was in good agreement with the observed value. The results of the R2, RMSE, and NSE were ranges of 0.77–0.90, 0.45–0.74 m, and 0.76–0.87, respectively. The errors were acceptable limits. The coupling model predicted the responses of different agricultural types and cropping scenarios to groundwater. Predictions showed that the groundwater level in the Cele Oasis remained stable under the current cropping scenario (100% cropping intensity), and that the groundwater level decreased slightly under the cropping scenario (110% cropping intensity and 130% cropping intensity). When the cropping scenario was at 170% cropping intensity, the groundwater level decreased rapidly, and the maximum drawdown value was 7 m. Therefore, the maximum cropping intensity of the Cele Oasis in the future should be 130% of the current cropping intensity

Monomicelle‐Directed Engineering of Strained Carbon Nanoribbons as Oxygen Reduction Catalyst

Abstract To date, precisely tailoring local active sites of well‐defined earth‐abundant metal‐free carbon‐based electrocatalysts for attractive electrocatalytic oxygen reduction reaction (ORR), remains challenging. Herein, the authors successfully introduce a strain effect on active C–C bonds adjacent to edged graphitic nitrogen (N), which raises appropriate spin‐polarization and charge density of carbon active sites and kinetically favor the facilitation of O2 adsorption and the activation of O‐containing intermediates. Thus, the constructed metal‐free carbon nanoribbons (CNRs‐C) with high‐curved edges exhibit outstanding ORR activity with half‐wave potentials of 0.78 and 0.9 V in 0.5 m H2SO4 and 0.1 m KOH, respectively, overwhelming the planar one (0.52 and 0.81 V) and the N‐doped carbon sheet (0.41 and 0.71 V). Especially in acidic media, the kinetic current density (Jk) is 18 times higher than that of the planar one and the N‐doped carbon sheet. Notably, these findings show the spin polarization of the asymmetric structure by introducing a strain effect on the C–C bonds for boosting ORR