A description of the transverse momentum distributions of charged particles produced in heavy ion collisions at RHIC and LHC energies

By assuming the existing of memory effects and long-range interactions in the hot and dense matter produced in high energy heavy ion collisions, the nonextensive statistics together with the relativistic hydrodynamics including phase transition is used to discuss the transverse momentum distributions of charged particles produced in heavy ion collisions. It is shown that the combined contributions from nonextensive statistics and hydrodynamics can give a good description to the experimental data in Au+Au collisions at sqrt(s_NN )= 200 GeV and in Pb+Pb collisions at sqrt(s_NN) )= 2.76 TeV for pi^(+ -) , K^(+ -) in the whole measured transverse momentum region, and for p(p-bar) in the region of p_T<= 2.0 GeV/c. This is different from our previous work, where, by using the conventional statistics plus hydrodynamics, the describable region is only limited in p_T<= 1.1 GeV/c.Comment: 14 pages, 3 figures, 2 table

CD73 promotes proliferation and migration of human cervical cancer cells independent of its enzyme activity

100 ΟM Adenosine treatment did not change the expression of EGFR, VEGF and Akt. (JPG 335 kb

Effects of suppressor of cytokine signaling 3 (SOCS3) on the development of colon cancer via regulation of HIF-1α

Purpose: To investigate the influence of suppressor of cytokine signaling 3 (SOCS3) on rats with colon cancer (CC). Methods: Sprague-Dawley (SD) rats were randomly divided into CC group and control group. CC models were constructed. The expression of SOCS3 in CC tissues was determined by quantitative real time-polymerase chain reaction (qRT-PCR). Hematoxylin-eosin staining (H&amp;E) was used to examine colon tissue morphology, while immunohistochemistry (IHC) staining assay was performed to determine the expression of SOCS3 protein in colon tissues. The content of HIF-1α, phosphorylated phosphatidylinositol 3-hydroxy kinase (p-PI3K), and phosphorylated protein kinase B (p-AKT) proteins was determined by Western blotting (WB). Results: Compared with that in the control group, the number of tumors in the CC group was significantly increased (p &lt; 0.05). Protein and messenger ribonucleic acid (mRNA) expressions of SOCS3 were down-regulated in CC group (p &lt; 0.05), while protein expressions of p-PI3K, p-AKT and HIF-1α were significantly elevated in CC group (p &lt; 0.05). Conclusion: SOCS3 is poorly expressed in CC rats, and promotes the expression of HIF-1α by activating PI3K/AKT signaling pathway. The findings, thus, provide a probable strategy for management of colon cancer

Effects of SOCS3 on the development of colon cancer via regulation of HIF-1α

Purpose: To investigate the influence of suppressor of cytokine signaling 3 (SOCS3) on rats with colon cancer (CC). Methods: Sprague-Dawley (SD) rats were randomly divided into CC group and control group, and then CC rat model was constructed. The expression of SOCS3 in CC tissues was determined by quantitative real time-polymerase chain reaction (qRT-PCR). Hematoxylin-eosin staining (H&amp;E) was used to examine colon tissue morphology. Immunohistochemistry (IHC) staining assay was performed to determine the expression of SOCS3 protein in colon tissues. The contents of HIF-1α, phosphorylated phosphatidylinositol 3-hydroxy kinase (p-PI3K), and phosphorylated protein kinase B (p-AKT) proteins were determined by Western blotting (WB). Results: Compared with that in the control group, the number of tumors in CC group was significantly increased (p &lt; 0.05). 2). On the other hand, protein and message ribonucleic acid (mRNA) expressions of SOCS3 were down-regulated in CC group (p &lt; 0.05). 3), while protein expressions of p-PI3K, p-AKT and HIF-1α were raised in CC group (p &lt; 0.05). Conclusion: SOCS3 is lowly expressed in CC rats, and promotes the expression of HIF-1α by activating PI3K/AKT signaling pathway. Thus, SOCS3 provides a therapeutic strategy for the management of colon cancer. Keywords: Colon cancer; Suppressor of cytokine signaling protein 3 (SOCS3); Hypoxia inducible factor-1

Magnetic Borophenes from an Evolutionary Search

A computational methodology based on ab initio evolutionary algorithms and spin-polarized density functional theory was developed to predict two-dimensional magnetic materials. Its application to a model system borophene reveals an unexpected rich magnetism and polymorphism. A metastable borophene with nonzero thickness is an antiferromagnetic semiconductor from first-principles calculations, and can be further tuned into a half-metal by finite electron doping. In this borophene, the buckling and coupling among three atomic layers are not only responsible for magnetism, but also result in an out-of-plane negative Poisson\u27s ratio under uniaxial tension, making it the first elemental material possessing auxetic and magnetic properties simultaneously

Observation of the chiral anomaly induced negative magneto-resistance in 3D Weyl semi-metal TaAs

Weyl semi-metal is the three dimensional analog of graphene. According to the quantum field theory, the appearance of Weyl points near the Fermi level will cause novel transport phenomena related to chiral anomaly. In the present paper, we report the first experimental evidence for the long-anticipated negative magneto-resistance generated by the chiral anomaly in a newly predicted time-reversal invariant Weyl semi-metal material TaAs. Clear Shubnikov de Haas oscillations (SdH) have been detected starting from very weak magnetic field. Analysis of the SdH peaks gives the Berry phase accumulated along the cyclotron orbits to be {\pi}, indicating the existence of Weyl points.Comment: Submitted in February'1