How Postpartum Women with Depressive Symptoms Manage Sleep Disruption and Fatigue

Postpartum sleep and fatigue have bidirectional relationships with depressive symptoms and challenge women\u27s everyday functioning. The everyday process of managing postpartum sleep and fatigue in the context of depressive symptoms remains unexplored. We conducted a grounded theory study with a sample of 19 women who screened positive on the Postpartum Depression Screening Scale (PDSS™) Short Form at 3 weeks postpartum. Women completed semi‐structured in‐home interviews and the full PDSS and Modified Fatigue Symptoms Checklist at 1, 3, and 6 months postpartum. The sample was on average 27 years old, with 2.8 children, and 63% were African‐American. They described a basic social process of Finding a Routine Together, during which women\u27s experiences with their infants progressed from Retreating at month 1 toward Finding a New Normal at month 6. In their work to Find a Routine Together, mothers’ patterns of change over time were continuous, gradual, or prolonged. Their progress was influenced by depressive symptoms, social support, work and daycare, stability in social circumstances, and underlying stressors. This study\u27s findings suggest the need to allocate resources and tailor interventions to meet the needs of women who are most vulnerable to the health effects of ongoing persistent severe fatigue, disordered sleep, and sub‐clinical and clinical levels of depressive symptoms

High power RF solid state power amplifier system

A high power, high frequency, solid state power amplifier system includes a plurality of input multiple port splitters for receiving a high-frequency input and for dividing the input into a plurality of outputs and a plurality of solid state amplifier units. Each amplifier unit includes a plurality of amplifiers, and each amplifier is individually connected to one of the outputs of multiport splitters and produces a corresponding amplified output. A plurality of multiport combiners combine the amplified outputs of the amplifiers of each of the amplifier units to a combined output. Automatic level control protection circuitry protects the amplifiers and maintains a substantial constant amplifier power output

Radio frequency power load and associated method

A radio frequency power load and associated method. A radio frequency power load apparatus includes a container and a fluid having an ion source therein, the fluid being contained in the container. Two conductors are immersed in the fluid. A radio frequency transmission system includes a radio frequency transmitter, a radio frequency amplifier connected to the transmitter and a radio frequency power load apparatus connected to the amplifier. The apparatus includes a fluid having an ion source therein, and two conductors immersed in the fluid. A method of dissipating power generated by a radio frequency transmission system includes the steps of: immersing two conductors of a radio frequency power load apparatus in a fluid having an ion source therein; and connecting the apparatus to an amplifier of the transmission system

Mars Rover Sample Return: A sample collection and analysis strategy for exobiology

For reasons defined elsewhere it is reasonable to search for biological signatures, both chemical and morphological, of extinct life on Mars. Life on Earth requries the presence of liquid water, therefore, it is important to explore sites on Mars where standing bodies of water may have once existed. Outcrops of layered deposits within the Valles Marineris appear to be ancient lake beds. Because the outcrops are well exposed, relatively shallow core samples would be very informative. The most important biological signature to detect would be organics, microfossils, or larger stromato-like structures, although the presence of cherts, carbonates, clays, and shales would be significant. In spite of the limitations of current robotics and pattern recognition, and the limitations of rover power, computation, Earth communication bandwidth, and time delays, a partial scenario was developed to implement such a scientific investigation. The rover instrumentation and the procedures and decisions and IR spectrometer are described in detail. Preliminary results from a collaborative effort are described, which indicate the rover will be able to autonomously detect stratification, and hence will ease the interpretation burden and lead to greater scientific productivity during the rover's lifetime

The Attitude of New South Wales Registered Nurses to Nursing Research: Factors and Influences

Attitude is considered to have a major influence on the way a person understands, learns and behaves in a given situation. The type of attitude held by an individual may be positive or negative. This study was concerned with Australian nurses' attitude to nursing research. Guided by the literature, attitude to nursing research was considered to consist of several elements that may be modified by other influences such as self-esteem, job satisfaction and the unique characteristics of the nurse. Factor analysis and reliability estimates of results following a mail survey of 1,304 registered nurses in NSW revealed four factors (subscales): motivation, knowledge, support and enactment that could represent the construct 'attitude to nursing research'. The explained variance for the factors was below an acceptable standard and Rasch measurement analysis was used to provide an alternative method for validation of the subscales and subscale interval level scores through logistic transformation of the data. Multiple regression analysis was used to test the model including the effects of self esteem and job satisfaction. The model failed to support the conceptual hypothesis. Multivariate analysis of variance, together with univariate analysis of significant relationships was conducted to determine differences with subgroups in the sample. Significant differences (

Reviews

Peter Pan\u27s Shadows in the Literary Imagination. Kirsten Stirling. Reviewed by Kayla McKinney Wiggins. C.S. Lewis and the Church: Essays in Honour of Walter Hooper. Ed. Judith Wolfe and B.N. Wolfe. Reviewed by Joe R. Christopher. Deadly Powers: Animal Predators and the Mythic Imagination. Paul A. Trout. Reviewed by Lizzy Walker. The Mythological Dimensions of Neil Gaiman. Anthony S. Burdge, Jessica Burke, and Kristine Larsen, eds. Reviewed by Nicholas Birns. Animals and Humans: Recurrent Symbiosis in Archaeology and Old Norse Religion. Kristina Jennbert. Reviewed by Emily E. Auger. Tolkien in Translation. Edited by Thomas Honegger. Reviewed by Harley J. Sims. Translating Tolkien: Text and Film. Ed. Thomas Honegger. Reviewed by Sara Brown. Critical Discourses on the Fantastic, 1712-1831. David Sandner. Reviewed by Joe Young. Arthurian Figures of History and Legend: A Biographical Dictionary. Frank D. Reno. Reviewed by Donald T. Williams. The Loss and the Silence: Aspects of Modernism in the Works of C.S. Lewis, J.RR. Tolkien, and Charles Williams. Margaret Hiley. Reviewed by Holly Ordway. Buffy and the Heroine’s Journey: Vampire Slayer as Feminine Chosen One. Valerie Estelle Frankel. Reviewed by Janet Brennan Croft. North Wind: A Journal of George MacDonald Studies. #30 (2011). Edited by Fernando Soto and John Pennington. Reviewed by Janet Brennan Croft. Mallorn: The Journal of the Tolkien Society. #53 (Spring 2012). Ed. Henry Gee. Reviewed by Janet Brennan Croft. Tolkien Studies: An Annual Scholarly Review. #9 (2012). Ed. Verlyn Flieger and Michael D.C. Drout. Reviewed by Janet Brennan Croft. Fastitocalon: Studies in Fantasticism Ancient to Modern. #2.1&2 (2011). Ed. Thomas Honegger and Fanfan Chen. Reviewed by Janet Brennan Croft

A simple group of order 44,352,000

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/46258/1/209_2005_Article_BF01110435.pd

Kindlin-1 promotes pulmonary breast cancer metastasis

Abstract In breast cancer, increased expression of the cytoskeletal adaptor protein Kindlin-1 has been linked to increased risks of lung metastasis, but the functional basis is unknown. Here, we show that in a mouse model of polyomavirus middle T antigen–induced mammary tumorigenesis, loss of Kindlin-1 reduced early pulmonary arrest and later development of lung metastasis. This phenotype relied on the ability of Kindlin-1 to bind and activate β integrin heterodimers. Kindlin-1 loss reduced α4 integrin–mediated adhesion of mammary tumor cells to the adhesion molecule VCAM-1 on endothelial cells. Treating mice with an anti–VCAM-1 blocking antibody prevented early pulmonary arrest. Kindlin-1 loss also resulted in reduced secretion of several factors linked to metastatic spread, including the lung metastasis regulator tenascin-C, showing that Kindlin-1 regulated metastatic dissemination by an additional mechanism in the tumor microenvironment. Overall, our results show that Kindlin-1 contributes functionally to early pulmonary metastasis of breast cancer. Significance: These findings provide a mechanistic proof in mice that Kindin-1, an integrin-binding adaptor protein, is a critical mediator of early lung metastasis of breast cancer. Cancer Res; 78(6); 1484–96. ©2018 AACR.</jats:p