Valutazione di alcuni indici di stress correlati al differente tipo di management in bovini affetti da Diarrea Virale Bovina/Malattia delle Mucose (BVD-MD) e Theileriosi

Convegno virtuale - "Risultati dell'attività di ricerca dell'IZS Sicilia" , 14 settembre 2020, Istituto Zooprofilattico Sperimentale della Sicilia, Palerm

A capability-based security approach to manage access control in the Internet of Things

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Advanced Services for Supply Chain Design Processes in Collaborative Networks

Part 10: Services DesignInternational audienceDesign and production of small series for specific customer target groups in collaborative networks can help companies to increase their competitiveness. This paper aims to describe a new framework of services for collaborative networking for on-demand productions. After describing the business processes that need to be supported by innovative tools for partner search and collaborative production planning, we describe the developed services and how they are integrated to ease the communication between different activities

Evaluation of cytokine polymorphisms (TNFα, IFNγ and IL-10) in Down patients with celiac disease

Background In Down syndrome there is an increased prevalence of coeliac disease, but the reasons for this association are yet unknown. Aims To evaluate a possible correlation between TNFα, IFNγ and IL-10 genotype polymorphisms with the susceptibility to coeliac disease in Down syndrome patients. Methods Single nucleotide polymorphisms of TNFα (−308G → A promoter region), IFNγ (+874T → A promoter region) and IL-10 (−1082G → A promoter region) have been studied in 10 Down patients with coeliac disease, in 40 Down patients without coeliac disease and in 220 healthy controls. Clinical features were also studied in coeliac disease–Down syndrome patients. Results The 10 coeliac disease–Down syndrome patients had a biopsy proven coeliac disease afterward a serological testing positive to antigliadin, antiendomysium and antitransglutaminase antibodies. Intestinal biopsy showed total atrophy in 6/10 and partial villous atrophy in 4/10 of them. All coeliac disease–Down syndrome patients had silent forms of coeliac disease and classical trisomy 21. No significant differences were observed for the IFNγ and IL-10 polymorphisms in the studied groups. A significant trend for increase of TNFα −308A positive frequency was observed in coeliac disease–Down syndrome patients compared to healthy controls (p = 0.043). Conclusions Single nucleotide polymorphisms of IFNγ and IL-10 do not play a role in predisposing Down syndrome patients to coeliac disease, while the TNFα −308 allele could be an additional genetic risk factor for coeliac disease in trisomy 21