Efeitos da Reeducação Postural Global em escolares com escoliose Global Posture Reeducation effects in students with scoliosis

O objetivo deste estudo foi analisar o efeito do método da Reeducação Postural Global (RPG) em escolares com diagnóstico de escoliose torácica não estrutural (ETNE). Os escolares com indicativo de ETNE ao exame postural e teste de Adams negativo foram encaminhados ao exame radiográfico para comprovação diagnóstica. Foram selecionados 20 participantes (11 meninos e 9 meninas, com 10±3 anos), divididos randomicamente em dois grupos homogêneos: o que realizou o RPG (GRPG) durante 12 semanas com duração de 25 a 30 minutos cada sessão, de acordo com o que aguentou permanecer na postura; e o grupo controle (GC), sem intervenção. Após três meses, os dois grupos repetiram a avaliação postural e o exame radiográfico. Para avaliação das estatísticas, foi utilizada análise de variância (ANOVA) univariada, com medidas repetidas, seguida do Post Hoc de Tukey para identificar as possíveis diferenças intra e intergrupos. O valor de &#945; foi de 0,05. O GRPG apresentou redução significativa no ângulo de Cobb na comparação intragrupo (&#916;%=-35,100; p=0,009), mas o GC não (&#916;%=9,520; p=0,789). Pode-se concluir que escolares submetidos ao método da RPG apresentaram melhora do quadro de escoliose torácica não estrutural.<br>The aim of this study was to analyze the effect of Global Reeducation Postural (RPG) method in scholars diagnosed with thoracic nonstructural scoliosis (ETNE). Scholars with indicative of ETNE to postural exam and Adams test negative were directed to radiographic exam to diagnostic. Twenty participants were selected (11 boys and 9 girls, 10±3 years old) and randomly divided in two homogeneous groups: group treated by RPG (GRPG) and control group (CG). The GRPG was submitted a RPG treatment during 12 weeks in sessions from 25 to 30 minutes in agreement with each student tolerance at posture. The CG didn't suffer intervention. After three months, both groups repeated the postural and radiographic exam. For statistics, it was used ANOVA univariated with repeated measures, followed by Tukey Post Hoc Test to identify the possible differences intra and intergroups. The &#945; value used was 0.05. The GRPG present significant reduction at Cobb angle between pre and posttest (&#916;%=-35.100; p=0.009), but the CG didn´t show (&#916;%=9.520; p=0.789). It was concluded that scholars submitted to RPG method presented improvement in thoracic nonstructural scoliosis

Exploring Stem Cells and Inflammation in Tendon Repair and Regeneration

Tendon injuries are frequent and are responsible for substantial morbidity both in sports and in the workplace. Despite the endogenous mechanisms of tendon repair and regeneration, tendon healing upon injury is slow and often insufficient to restore complete biomechanics functionality. Inflammation has a pivotal role in tendon healing and failed healing responses contribute to the progression of tendinopathies. However, the molecular and cellular mechanisms involved are poorly understood requiring further insights. During inflammation, bioactive molecules such as cytokines secreted locally at the injury site, influence resident stem cells that contribute as modulatory agents over the niche towards homeostasis, holding great promise as therapeutic agents for tendon pathological conditions associated to unresolved inflammation and failed healing. This review overviews the role of cytokines and resident cells, focusing on the participation of tendon stem cell population in inflammation and tendon healing upon injury and their potential action in resolution of pathological conditionsFundação para a Ciência e Tecnologia (FCT) for the doctoral grant PD/BD/128089/2016, the project NORTE-01-0145-FEDER-000021 supported by Norte Portugal Regional Operational Programme (NORTE 2020) and HORIZON 2020 under the TEAMING GRANT agreement No 739572 – The Discoveries CTRinfo:eu-repo/semantics/publishedVersio