31 research outputs found
Mean platelet volume and its relationship with carotid atherosclerosis in subjects with non-alcoholic fatty liver disease
The effects of transversus abdominis plane block on analgesic and anesthetic consumption during total abdominal hysterectomy: a randomized controlled study
Background and objectives: A transversus abdominis plane block is a peripheral block method that has been used successfully for pain relief after total abdominal hysterectomy. However, the effects of the combination of the transversus abdominis plane block and general anesthesia on analgesic and anesthetic requirements remain unclear. This randomized placebo-controlled study is aimed to evaluate the effects of transversus abdominis plane block on analgesic and anesthetic consumption during total abdominal hysterectomy under general anesthesia. Methods: Sixty-six women undergoing total abdominal hysterectomy were randomized into two groups to receive general anesthesia alone (control group) or with transversus abdominis plane block using 20 mL of 0.25% bupivacaine (transversus abdominis plane group). Intraoperative remifentanil and sevoflurane consumption were recorded. We also evaluated the postoperative pain, nausea, quality of recovery scores and rescue analgesic requirement during postoperative 24 hours. Results: The total remifentanil and sevoflurane consumption is significantly lower in transversus abdominis plane group; respectively mean (SD) 0.130 (0.25) vs. 0.094 (0.02) mcg.kgâ1.minâ1; p < 0.01 and 0.295 (0.05) vs. 0.243 (0.06) mL.minâ1; p < 0.01. In the postoperative period, pain scores were significantly reduced in transversus abdominis plane group soon after surgery; median (range) 6 (2â10) vs. 3 (0â5); p < 0.001, at 2 h (5 [3â9] vs. 2.5 [0â6]; p < 0.001), at 6 h (4 [2â7] vs. 3[0â6], p < 0.001), at 12 h (3.5 [1â6] vs. 2 [1â5]; p = 0.003). The patients in the transversus abdominis plane group had significantly higher QoR-40 scores 190.5 (175â197) vs. 176.5 (141â187); p < 0.001). Conclusion: Combining transversus abdominis plane block with general anesthesia can provide reduced opioid and anesthetic consumption and can improve postoperative pain and quality of recovery scores in patients undergoing total abdominal hysterectomy. Resumo: Justificativa e objetivos: O bloqueio do plano transverso abdominal Ă© um mĂ©todo de bloqueio perifĂ©rico que tem sido usado com sucesso para alĂvio da dor apĂłs histerectomia abdominal total. No entanto, os efeitos da combinação do bloqueio do plano transverso abdominal e da anestesia geral sobre a necessidade de analgĂ©sico e anestĂ©sico ainda nĂŁo estĂŁo claros. Este estudo randĂŽmico e controlado com placebo tem como objetivo avaliar os efeitos do bloqueio do plano transverso abdominal sobre o consumo de analgĂ©sico e anestĂ©sico durante histerectomia abdominal total sob anestesia geral. MĂ©todos: Foram randomizadas em dois grupos 66 mulheres submetidas Ă histerectomia abdominal total para receber apenas anestesia geral (grupo controle) ou associada a bloqueio do plano transverso abdominal usando 20 mL de bupivacaĂna a 0,25% (grupo plano transverso abdominal). O consumo de remifentanil e sevoflurano no perĂodo intraoperatĂłrio foi registrado. TambĂ©m avaliamos a dor pĂłs-cirurgia, nĂĄusea, qualidade dos escores de recuperação e necessidade de analgĂ©sico de resgate durante as 24 horas de pĂłs-operatĂłrio. Resultados: O consumo total de remifentanil e sevoflurano foi significativamente menor no grupo plano transverso abdominal, respectivamente, mĂ©dia (DP): 0,130 (0,25) vs. 0,094 (0,02) mcg.kgâ1.minâ1; p < 0,01 e 0,295 (0,05) vs. 0,243 (0,06) mL.minâ1; p < 0,01. No pĂłs-operatĂłrio, os escores de dor foram significativamente reduzidos no grupo plano transverso abdominal logo apĂłs a cirurgia; mediana (intervalo): 6 (2-10) vs. 3 (0-5); p < 0,001, em 2 h (5 [3-9] vs. 2,5 [0-6]; p < 0,001), em 6 h (4 [2-7] vs. 3 [0-6], p < 0,001), em 12 h (3,5 [1-6] vs. 2 [1-5]; p = 0,003). As pacientes do grupo plano transverso abdominal apresentaram escores QoR-40 significativamente maiores: 190,5 (175-197) vs. 176,5 (141-187); p < 0,001). ConclusĂŁo: A combinação de bloqueio do plano transverso abdominal e anestesia geral pode proporcionar um consumo reduzido de opioides e anestĂ©sicos e melhorar a dor pĂłs-cirĂșrgica e a qualidade dos escores de recuperação em pacientes submetidas Ă histerectomia abdominal total. Keywords: Anesthesia, general, Anesthesia, regional, Transversus abdominis plane block, Hysterectomy, Palavras-chave: Anestesia, geral, Anestesia, regional, Bloqueio do plano transverso abdominal, Histerectomi
The effects of transversus abdominis plane block on analgesic and anesthetic consumption during total abdominal hysterectomy: a randomized controlled study
Abstract Background and objectives: A transversus abdominis plane block is a peripheral block method that has been used successfully for pain relief after total abdominal hysterectomy. However, the effects of the combination of the transversus abdominis plane block and general anesthesia on analgesic and anesthetic requirements remain unclear. This randomized placebo-controlled study is aimed to evaluate the effects of transversus abdominis plane block on analgesic and anesthetic consumption during total abdominal hysterectomy under general anesthesia. Methods: Sixty-six women undergoing total abdominal hysterectomy were randomized into two groups to receive general anesthesia alone (control group) or with transversus abdominis plane block using 20 mL of 0.25% bupivacaine (transversus abdominis plane group). Intraoperative remifentanil and sevoflurane consumption were recorded. We also evaluated the postoperative pain, nausea, quality of recovery scores and rescue analgesic requirement during postoperative 24 hours. Results: The total remifentanil and sevoflurane consumption is significantly lower in transversus abdominis plane group; respectively mean (SD) 0.130 (0.25) vs. 0.094 (0.02) mcg.kg-1.min-1; p < 0.01 and 0.295 (0.05) vs. 0.243 (0.06) mL.min-1; p < 0.01. In the postoperative period, pain scores were significantly reduced in transversus abdominis plane group soon after surgery; median (range) 6 (2-10) vs. 3 (0-5); p < 0.001, at 2 h (5 [3-9] vs. 2.5 [0-6]; p < 0.001), at 6 h (4 [2-7] vs. 3[0-6], p < 0.001), at 12 h (3.5 [1-6] vs. 2 [1-5]; p = 0.003). The patients in the transversus abdominis plane group had significantly higher QoR-40 scores 190.5 (175-197) vs. 176.5 (141-187); p < 0.001). Conclusion: Combining transversus abdominis plane block with general anesthesia can provide reduced opioid and anesthetic consumption and can improve postoperative pain and quality of recovery scores in patients undergoing total abdominal hysterectomy
From extended feature models to constraint logic programming
Since feature models for realistic product families may be quite complicated, the automated analysis of feature models is desirable. Although several approaches reported in the literature address this issue, complex cross-tree relationships involving attributes in extended feature models have not been handled. In this article, we introduce a mapping from extended feature models to constraint logic programming over finite domains. This mapping is used to translate into constraint logic programs; basic, cardinality-based and extended feature models, which can include complex cross-tree relationships involving attributes. This translation enables the use of off-the-shelf constraint solvers for the automated analysis of extended feature models involving such complex relationships. We also present the performance results of some well-known analysis operations on an example translated model