Mass estimates from optical modelling of the new TRAPUM redback PSR J1910−5320

Spider pulsars continue to provide promising candidates for neutron star mass measurements. Here we present the discovery of PSR J1910−5320, a new millisecond pulsar discovered in a MeerKAT observation of an unidentified Fermi-LAT gamma-ray source. This pulsar is coincident with a recently identified candidate redback binary, independently discovered through its periodic optical flux and radial velocity. New multicolour optical light curves obtained with ULTRACAM/New Technology Telescope in combination with MeerKAT timing and updated SOAR/Goodman spectroscopic radial velocity measurements allow a mass constraint for PSR J1910−5320. icarus optical light curve modelling, with streamlined radial velocity fitting, constrains the orbital inclination and companion velocity, unlocking the binary mass function given the precise radio ephemeris. Our modelling aims to unite the photometric and spectroscopic measurements available by fitting each simultaneously to the same underlying physical model, ensuring self-consistency. This targets centre-of-light radial velocity corrections necessitated by the irradiation endemic to spider systems. Depending on the gravity darkening prescription used, we find a moderate neutron star mass of either 1.6 ± 0.2 or 1.4 ± 0.2 M⊙. The companion mass of either 0.45 ± 0.04 or $0.43^{+0.04}_{-0.03}$M⊙ also further confirms PSR J1910−5320 as an irradiated redback spider pulsar

Mycobacterium ulcerans and Buruli Ulcer

Buruli Ulcer (BU) is the third most common mycobacterium disease following only tuberculosis and leprosy. Though BU is thought to be associated with large-and small-scale disturbances to the landscape and bodies of water frequented by human populations, primary prevention of BU is difficult because the mode of transmission is not known. This chapter reviews the most common environmental risk factors for BU and recent research into understanding its transmission. It is predicted that the proteins affected by mycolactone may share an underlying mechanism of production that could explain their co-regulation. Early work on the mechanism of suppression by mycolac-tone was carried out in Jurkat T cells using ASLs and focused on the suppression of IL-2 production. A multidisciplinary approach to treatment and patient care is essential for optimizing treatment outcomes. Physiotherapy is paramount minimizing and/or preventing disabilities