The effects of flavonoids on cardiovascular health: a review of human intervention trials and implications for cerebrovascular function

Research has suggested a number of beneficial effects arising from the consumption of dietary flavonoids, found in foods such as cocoa, apples, tea, citrus fruits and berries on cardiovascular risk factors such as high blood pressure and endothelial dysfunction. These effects are thought to have a significant impact upon both vascular and cerebrovascular health, ultimately with the potential to prevent cardiovascular and potentially neurodegenerative disease with a vascular component, for example vascular dementia. This review explores the current evidence for the effects of flavonoid supplementation on human endothelial function and both peripheral and cerebral blood flow (CBF). Evidence presented includes their potential to reduce blood pressure in hypertensive individuals, as well as increasing peripheral blood perfusion and promoting CBF in both healthy and at-risk populations. However, there is great variation in the literature due to the heterogeneous nature of the randomised controlled trials conducted. As such, there is a clear need for further research and understanding within this area in order to maximise potential health benefits

Long-range sound-mediated dark soliton interactions in trapped atomic condensates

A long-range soliton interaction is discussed whereby two or more dark solitons interact in an inhomogeneous atomic condensate, modifying their respective dynamics via the exchange of sound waves without ever coming into direct contact. An idealized double well geometry is shown to yield perfect energy transfer and complete periodic identity reversal of the two solitons. Two experimentally relevant geometries are analyzed which should enable the observation of this long-range interaction

Slow 4He^{4}He Quenches Produce Fuzzy, Transient Vortices

We examine the Zurek scenario for the production of vortices in quenches of liquid $^{4}He$ in the light of recent experiments. Extending our previous results to later times, we argue that short wavelength thermal fluctuations make vortices poorly defined until after the transition has occurred. Further, if and when vortices appear, it is plausible that that they will decay faster than anticipated from turbulence experiments, irrespective of quench rates.Comment: 4 pages, Revtex file, no figures Apart from a more appropriate title, this paper differs from its predecessor by including temperature, as well as pressure, quenche

The asymptotic quasi-stationary states of the two-dimensional magnetically confined plasma and of the planetary atmosphere

We derive the differential equation governing the asymptotic quasi-stationary states of the two dimensional plasma immersed in a strong confining magnetic field and of the planetary atmosphere. These two systems are related by the property that there is an intrinsic constant length: the Larmor radius and respectively the Rossby radius and a condensate of the vorticity field in the unperturbed state related to the cyclotronic gyration and respectively to the Coriolis frequency. Although the closest physical model is the Charney-Hasegawa-Mima (CHM) equation, our model is more general and is related to the system consisting of a discrete set of point-like vortices interacting in plane by a short range potential. A field-theoretical formalism is developed for describing the continuous version of this system. The action functional can be written in the Bogomolnyi form (emphasizing the role of Self-Duality of the asymptotic states) but the minimum energy is no more topological and the asymptotic structures appear to be non-stationary, which is a major difference with respect to traditional topological vortex solutions. Versions of this field theory are discussed and we find arguments in favor of a particular form of the equation. We comment upon the significant difference between the CHM fluid/plasma and the Euler fluid and respectively the Abelian-Higgs vortex models.Comment: Latex 126 pages, 7 eps figures included. Discussion on various forms of the equatio

Heavy hydrocarbon main injector technology program

The Heavy Hydrocarbon Main Injector Program was an analytical, design, and test program to demonstrate an injection concept applicable to an Isolated Combustion Compartment of a full-scale, high pressure, LOX/RP-1 engine. Several injector patterns were tested in a 3.4-in. combustor. Based on these results, features of the most promising injector design were incorporated into a 5.7-in. injector which was then hot-fire tested. In turn, a preliminary design of a 5-compartment 2D combustor was based on this pattern. Also the additional subscale injector testing and analysis was performed with an emphasis on improving analytical techniques and acoustic cavity design methodology. Several of the existing 3.5-in. diameter injectors were hot-fire tested with and without acoustic cavities for spontaneous and dynamic stability characteristics

Mydriatics: Drop the dose

This study investigated the difference in pupillary dilation between a normal dose and a substandard dose of a topical ophthalmic mydriatic agent, the combination of hydroxyamphetamine hydrobromide 1% and tropicamide 0.25% (Paremyd™ solution). The manufacturer\u27s recommended dosage is 1-2 drops per eye. A typical opthalmic drop ranges in volume from 30 - 75. We hypothesized that a small, substandard dose of 10 will create a pupillary dilation clinically and statistically equivalent to that of the larger, standard dose of 30 in part due to the reflex tear response and increased lacrimal drainage. Our research found that the smaller dose of the mydriatic does indeed provide a clinically and statistically equivalent pupillary dilation to the larger dose. Clinically, the use of a reduced dose of a topical mydriatic will reduce the inherent risks and side effects to the patient (especially to the high-risk patient), while still allowing the eye care practitioner ample pupillary dilation to provide a quality dilated fundus examination

Phase diagram of quantized vortices in a trapped Bose-Einstein condensed gas

We investigate the thermodynamic stability of quantized vortices in a dilute Bose gas confined by a rotating harmonic trap at finite temperature. Interatomic forces play a crucial role in characterizing the resulting phase diagram, especially in the large $N$ Thomas-Fermi regime. We show that the critical temperature for the creation of stable vortices exhibits a maximum as a function of the frequency of the rotating trap and that the corresponding transition is associated with a discontinuity in the number of atoms in the condensate. Possible strategies for approaching the vortical region are discussed.Comment: Revtex, 4 pages, 2 figure