Versatility of an 810 NM Diode Laser in Pediatric Dentistry

Purpose: During the last few years, the use of laser techniques has dominated the dentistry world as an alternative to different traditional methods or in combination with these. Diode laser is the most frequently used in dentistry due to its reliability, versatility and convenience, together with its handiness and simple setting-up. The aim of this paper is to review the use of diode laser (810 nm) in pediatric dentistry. Methods: We illustrate, according to the recent literature review, the clinical approach in deciduous teeth endodontics (like pulpotomy and root canal therapy) and in soft tissues surgery with description of techniques used in labial and lingual fraenectomy, operculectomy for tooth retention and hypertrophic lesions removal. Results: 810 nm diode laser has been used in all these different therapies at 0,8 to 3 W power either in continuous or pulsed mode. Diode laser has one of the most versatile ranges of wavelengths available due to the number of different therapies that can be performed in several tissues

Riga-Fede Disease and Neonatal Teeth

AIM: The aim of this study is to present a case of Riga-Fede disease (RFD). RFD is a benign and uncommon mucosal disorder, characterized by an ulceration of the tongue, often caused by repetitive traumatic injuries due to backward and forward movements of the tongue over the mandibular anterior incisors. RFD is most commonly associated with the eruption of primary lower incisor in older infants or natal-neonatal teeth in newborns. METHODS: A 2-month-old female infant was referred to our Paediatric Dentistry Unit for ulceration (13 mm diameter) on the ventral surface of the tongue and neonatal teeth. The extraction of neonatal teeth was selected as treatment of choice, over more conservative treatments, for the rapid resolution of the lesion and for the limited risk of inadequate nutrients intake. The extracted teeth underwent a macroscopic/microscopic examination. The complete healing of the lesion took 4 weeks; subsequently, the infant, revised at the 1-year follow-up visit. CONCLUSION: Early detection of RFD is recommended because such lesions properly may induce deformity or mutilation of tongue, dehydration, inadequate nutrients intake by the infant and growth retardatio

Cardiovascular Disease and Its Association With Histological Changes of the Left Stellate Ganglion

Mounting evidence has demonstrated that the autonomic system plays a role in the morbidity and mortality of certain cardiovascular disease states. Ventricular arrhythmias have been associated with the level of sympathetic activation. We attempted to determine if the presence of fibrosis, a marker for previous ischemic events, correlates with an increase in the number of left stellate ganglion nerve cell bodies which is indicative of hypersympathetic stimulation to the myocardial tissue. Left stellate ganglia were removed, sectioned and prepared using hematoxylin and eosin and Masson’s trichrome stain. The interventricular septum of the heart corresponding to the stellate ganglion samples were removed, serially sectioned, and stained with hematoxylin and eosin and Masson’s trichrome stain. The samples were described using a grading scale to quantify the percentage of fibrosis. Ganglion nerve cell bodies were then individually counted in three separate high-powered fields. A student’s T-test was used to statistically evaluate the data. Stellate ganglions were sampled from 32 cadavers. Fibrosis was present within 72% (23/32) of the interventricular septums that were sampled. Nine interventricular septums were found to be free of fibrosis. For those interventricular septums that were positive for the presence of fibrosis, the mean left stellate ganglion nerve cell bodies was 39.8 (Range: 26–51). For those interventricular septums that were negative for the presence of fibrosis, the mean left stellate ganglion nerve cell bodies was 34.3 (Range: 27–46). The difference between the mean nerve cell bodies for interventricular septums with fibrosis and without fibrosis was found to be statistically significant (P = 0.048). Histological changes in terms of the number of left stellate ganglion nerve cell bodies seem to be dependent upon the presence of fibrosis within the interventricular septum. Considering fibrosis of the interventricular septum is a marker for previous ischemic events, an increase in the number of nerve cell bodies of the left stellate ganglion in the presence of fibrosis suggests an association does exist between hypersympathetic stimulation to the myocardial tissue and myocardial infarction. Further research into this association is warranted in order to determine if left stellate ganglion blockade is a viable treatment option for arrhythmias following myocardial infarctions

Specialized metabolites and valuable molecules in crop and medicinal plants: The evolution of their use and strategies for their production

Plants naturally produce a terrific diversity of molecules, which we exploit for promoting our overall well-being. Plants are also green factories. Indeed, they may be exploited to biosynthesize bioactive molecules, proteins, carbohydrates and biopolymers for sustainable and large-scale production. These molecules are easily converted into commodities such as pharmaceuticals, antioxidants, food, feed and biofuels for multiple industrial processes. Novel plant biotechnological, genetics and metabolic insights ensure and increase the applicability of plant-derived compounds in several industrial sectors. In particular, synergy between disciplines, including apparently distant ones such as plant physiology, pharmacology, ‘omics sciences, bioinformatics and nanotechnology paves the path to novel applications of the so-called molecular farming. We present an overview of the novel studies recently published regarding these issues in the hope to have brought out all the interesting aspects of these published studies

Relationship between postoperative venous thromboembolism and hemorrhage in patients undergoing total thyroidectomy without preoperative prophylaxis

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Jefferson Health: Clinical Integration: Focus on Value

Anne Docimo, MD, MBA, Senior Executive Vice President and Chief Medical Officer at the Jefferson Health System. Dr. Docimo, served as CMO for the University of Pittsburgh Medical Center (UPMC) Health Plan and as Senior Medical Director for the Hospital Division of UPMC, a non-profit integrated health system operating more than 20 academic, community and specialty hospitals. All medical programs at UPMC Health Plan and all activities related to the delivery of health care, reported up through Dr. Docimo. Prior to her roles at UPMC, she was Director of Urgent Care and Community Medicine at Johns Hopkins Health System. This Forum presentation will provide an overview of the various forces driving healthcare reform. The notion of patients as consumers and game changers will be discussed along with ways in which we can provide value to consumers. Dr. Docimo received her bachelor\u27s degree from the University of Notre Dame and her MD from Johns Hopkins School of Medicine. She completed her residency in emergency medicine at Georgetown University/George Washington University, and earned a Certificate in Medical Management from Johns Hopkins University. Dr. Docimo also has an MBA from Johns Hopkins University. Presentation: 51 minute