32 research outputs found
Assessing Physical Activity During a High Altitude Trek in Peru
Please view abstract in the attached PDF file
The Association Between Body Composition and Acute Mountain Sickness
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Greater Energy Cost During Standardized Walking is Associated With Diminished Fitness in Older Adults
Please refer to the pdf version of the abstract located adjacent to the title
Effects of Weight Loss and Exercise In Older Adults With Apnea
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Assessing the Prevalence of Sleep Apnea among Collegiate Football Players
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Aerobic Capacity Independently Predicts Central Augmentation Index Among Apparently Healthy Adults
poste
Biphasic responses of the brachial artery diameter following forearm occlusion: a blunted response in the elderly
BACKGROUND: The purpose was to examine the temporal response of the brachial artery diameter following 5 minutes of forearm occlusion in young men. A secondary objective was to compare the main features of the temporal pattern between young and old. METHODS: Sixteen young (28 ± 8 yrs) and fifteen older (85 ± 8 yrs) men underwent high-resolution ultrasonography of the brachial artery before and after five minutes of forearm occlusion. RESULTS: Following release of the pressure cuff the brachial artery diameter exhibits a temporal biphasic response. Initially, there is a significant reduction in brachial diameter (NIL) compared to baseline (BASE), followed by a rapid increase to a PEAK at 41 sec post release. When comparing the magnitude of the decrease in diameter and the Brachial Artery Flow Mediated Dilation (BAFMD) between Young and Old, older subjects demonstrated a blunted response (Magnitude of Decrease: Young: 2.0%; Old: 0.4%, p = 0.015, and BAFMD: Young: 7.7%; Old: 2.3%, p = 0.001). Finally, a significant relationship was noted between the magnitude of decrease and BAFMD (r = -0.44, p = 0.04). CONCLUSION: Examination of the temporal response of the brachial artery diameter following 5 minutes of forearm occlusion reveals a biphasic pattern in all participants. Specific features of this pattern are blunted in older adults compared with younger subjects. Finally, the magnitude of the drop in diameter following forearm occlusion correlates with the magnitude of the BAFMD