Immersive technologies as a solution for general data protection regulation in Europe and impact on the COVID-19 pandemic

Background: General data protection regulation (GDPR) provides rules according to which datashould be managed and processed in a secure and appropriate way for patient requirements and security.Currently, everyone in Europe is covered by GDPR. Thus, the medical practice also requires accessto patient data in a safe and secure way.Methods: Holographic technology allows users to see everything visible on a computer screen in a newand less restricted way, i.e. without the limitations of traditional computers and screens.Results: In this study, a three-dimensional holographic doctors’ assistant is designed and implementedin a way that meets the GDPR requirements. The HoloView application, which is tailored to run onMicrosoft HoloLens, is proposed toallow display and access to personal data and so-called sensitiveinformation of all individual patients without the risk that it will be presented to unauthorized persons.Conclusions: To enhance the user experience and remain consistent with GSPR, a holographic deskis proposed that allows displaying patient data and sensitive information only in front of the doctor’seyes using mixed reality glasses. Last but not least, it boasts of a reduction in infection risk for the staffduring the COVID-19 pandemic, affording medical care to be carried out by as few doctors as possible

Media - popular culture - politics: interactions and new phenomena

Praca recenzowana / peer-reviewed pape

Mixed reality-based technology to visualize and facilitate treatment planning of impacted teeth: Proof of concept.

OBJECTIVE We propose a method utilizing mixed reality (MR) goggles (HoloLens 2, Microsoft) to facilitate impacted canine alignment, as planning the traction direction and force delivery could benefit from 3D data visualization using mixed reality (MR). METHODS Cone-beam CT scans featuring isometric resolution and low noise-to-signal ratio were semi-automatically segmented in Inobitec software. The exported 3D mesh (OBJ file) was then optimized for the HoloLens 2. Using the Unreal Engine environment, we developed an application for the HoloLens 2, implementing HoloLens SDK and UX Tools. Adjustable pointers were added for planning attachment placement, traction direction, and point of force application. The visualization was presented to participants of a course on impacted teeth treatment, followed by a 10-question survey addressing potential advantages (5-point scale: 1 = totally agree, 5 = totally disagree). RESULTS Out of 38 respondents, 44.7% were orthodontists, 34.2% dentists, 15.8% dental students, and 5.3% dental technicians. Most respondents (44.7%) were between 35 and 44 years old, and only 1 (2.6%) respondent was 55-64 years old. Median answers for six questions were 'totally agree' (25th percentile 1, 75th percentile 2) and for four questions 'agree' (25th percentile 1, 75th percentile 2). No correlation was found between age, profession, and responses. CONCLUSION Our method generated substantial interest among clinicians. The initial responses affirm the potential benefits, supporting the continued exploration of MR-based techniques for the treatment of impacted teeth. However, the recommendation for widespread use awaits validation through clinical trials

Cold-crystallization and physical stability of glassy carbamazepine

Physical stability as well as isothermal and non-isothermal cold-crystallization of quench-cooled drug carbamazepine (CBZ) was studied using powder X-ray diffraction (XRD), differential scanning calorimetry (DSC) and Fourier-transform infrared spectroscopy (FT-IR). Three phase transitions on heating were reported: glass softening (∼329 K), cold-crystallization (∼389 K) and melting (∼463 K). XRD results and evaluation of DSC data using Adam-Gibbs model extended to the glassy state revealed, that the amorphous sample of CBZ remains physically stable for 8 h at room temperature (i.e. about 30 K below glass transition temperature). Isothermal XRD measurements showed that amorphous CBZ is prone to rapid nucleation even about 50 K below the glass transition, but crystal growth is considerably slowed down in such conditions. Fragility parameter m was calculated and quench-cooled CBZ was identified as moderately fragile glass. FT-IR measurements coupled with moving-window two-dimensional correlation spectroscopy proved that changes in vibrational dynamics accompanied all phase transitions. Considerable strengthening of hydrogen bonding was observed during cold crystallization