12 research outputs found
Mutations in human genes that increase the risk for severe influenza infection
The system of genetic control of innate immune responses to influenza infection and gene function allows for the development of systemic treatment of influenza with a focus on the phenotype of mutations based on individual genetic susceptibility to severe disease and/or the development of complications
Socio-communication problems of distance education
Russian higher education, under the influence of globalization and the need for integration into the global scientific community, is faced with such problems as preservation quality of information flows (fundamental education), training a creative specialist, and the problem of an effective organizational form of education. Distance education as an opportunity to gain knowledge has existed for a very long time and there has always been a dismissive distrust of them in universities. However, directly or indirectly, the crisis caused stakeholders of education, as the most massive part of the world's population, to the necessity of making and testing distance forms of learning and communication to the full extent. The study analyzed the opinions of students about the possibilities and limitations of online learning, the degree of trust in the learning outcomes, and the quality and applicability of gain knowledge. The sociopsychological conditions for completing educational programs are also evaluated. © 2020 IEEE
Interaction of subjects of information and digital security: country-specific analysis
Воронин Юрий Александрович – доктор юридических наук, профессор кафедры уголовного и уголовно-исполнительного права, криминологии, Южно-Уральский государственный университет, г. Челябинск. E-mail: [email protected].
Дмитриева Анна Александровна – доктор юридических наук, заведующий кафедрой уголовного и уголовно-исполнительного права, криминологии, Южно-Уральский государственный университет, г. Челябинск. E-mail: [email protected].
Кухтина Татьяна Владимировна – старший преподаватель кафедры уголовного и уголовно-исполнительного права, криминологии, Южно-Уральский государственный университет, г. Челябинск, Российская Федерация. E-mail: [email protected]. Yuri Alexandrovich Voronin – Doctor of Sciences (Law), Professor of the Department of Crim-inal and Criminal-Executive Law, Criminology, South Ural State University, Chelyabinsk, Russian Federation. E-mail: [email protected]. Anna Alexandrovna Dmitrieva – Doctor of Sciences (Law), Head of the Department of Criminal and Criminal-Executive Law, Criminology, South Ural State University, Chelyabinsk, Russian Federa-tion. E-mail: [email protected].
Tatyana Vladimirovna Kukhtina – Research assistant of the Department of Criminal and Crim-inal-Executive Law, Criminology, South Ural State University, Chelyabinsk, Russian Federation. E-mail: [email protected].Интенсивный рост информационно-цифровой преступности в современном мире диктует настоятельную необходимость взаимодействия между субъектами, противодействующими ей как на национальном, так и межгосударственном уровнях. В полной мере это относится к России, Великобритании и США, в которых система борьбы с данной категорией преступлений складывается из совместных усилий целого ряда субъектов. При этом все в большей мере указанная система базируется на использовании современных достижений науки, совершенствовании информационно-коммуникационных технологий. Особенно важную роль в каждой из упомянутых стран играют сотрудничество в сфере межведомственного взаимодействия национальных правоохранительных структур, координация этой деятельности с органами власти и управления, институтами гражданского общества. Кроме того, как свидетельствует страноведческий анализ практики борьбы с цифровой преступностью, чрезвычайно актуальным является межгосударственное сотрудничество, в частности обмен оперативной информацией для успешного расследования соответствующей категории уголовных дел. Следует подчеркнуть, что эффективность всех перечисленных элементов взаимодействия субъектов противостояния с информационно-цифровой преступностью достигается лишь при добросовестном выполнении ими взятых на себя обязательств. The intensive growth of information and digital crime in the modern world dictates the urgent need for interaction between entities that counteract it both at the national and interstate levels. This fully applies to Russia, the United Kingdom and the United States, where the system of combating this category of crimes consists of the joint efforts of a number of subjects. At the same time, to an increasing extent, this system is based on the use of modern scientific achievements, the improvement of information and communication technologies. A particularly important role in each of the above-mentioned countries is played by cooperation in the field of interdepartmental interaction of national law enforcement agencies, coordination of this activity with authorities and management bodies, civil society institutions. In addition, as evidenced by the country-specific analysis of the practice of com-bating digital crime, interstate cooperation is extremely relevant, in particular, the exchange of operational information for the successful investigation of the relevant category of criminal cases. It should be emphasized that the effectiveness of all these elements of interaction between the subjects of confrontation with information and digital crime is achieved only if they faithfully fulfill their obligation
Development and concentration efficiency study of enterprises innovation activity in real sector of economy
The relevance of the issue under investigation is reasoned by the fact that in growing global competition and expansion context, on the one hand, and economic constraints related to geopolitical tensions, on the other hand, a key factor in the enterprises competitiveness and priority positions achievement in the world market will be their transition to innovative production technologies and business. Topical and promising one in this case is to achieve competitive excellence, increase business efficiency through the innovations' projecting and commercialization. The paper purpose is to investigate the efficiency and specificity level of the ongoing innovation processes in the real sector of the economy as innovative transformations key segment and the basis for increasing the territory competitiveness. The leading method to the problem study is the method of systemic economic analysis, which allows revealing the essence, regularities, trends of the processes occurring at all levels of innovative transformations. To assess the innovative activity concentration and enterprises' innovative development nature, it is proposed to use analysis methods based on the cost efficiency evaluation, depending on the effect magnitude achieved as a result of innovations practical use, enabling to diagnose competitive and non-competitive producing groups, to determine the resource and innovation potential with strategy development further construction. The research materials can be used in innovative transformations management in organizations of the real sector of the economy, economic regional systems formation, the territories competitiveness management and innovative development's strategies construction. © 2017, Authors
Development and concentration efficiency study of enterprises innovation activity in real sector of economy
The relevance of the issue under investigation is reasoned by the fact that in growing global competition and expansion context, on the one hand, and economic constraints related to geopolitical tensions, on the other hand, a key factor in the enterprises competitiveness and priority positions achievement in the world market will be their transition to innovative production technologies and business. Topical and promising one in this case is to achieve competitive excellence, increase business efficiency through the innovations' projecting and commercialization. The paper purpose is to investigate the efficiency and specificity level of the ongoing innovation processes in the real sector of the economy as innovative transformations key segment and the basis for increasing the territory competitiveness. The leading method to the problem study is the method of systemic economic analysis, which allows revealing the essence, regularities, trends of the processes occurring at all levels of innovative transformations. To assess the innovative activity concentration and enterprises' innovative development nature, it is proposed to use analysis methods based on the cost efficiency evaluation, depending on the effect magnitude achieved as a result of innovations practical use, enabling to diagnose competitive and non-competitive producing groups, to determine the resource and innovation potential with strategy development further construction. The research materials can be used in innovative transformations management in organizations of the real sector of the economy, economic regional systems formation, the territories competitiveness management and innovative development's strategies construction. © 2017, Authors
The Olkhon metamorphic terrane in the Baikal region: An Early Paleozoic collage of Neoproterozoic active margin fragments
Trophic associations and specialization of phytophagous beetles (Coleoptera: Chrysomeloidea, Curculionoidea) in the east of the Russian Plain
РЕКОМЕНДАЦИИ ПО ВЕДЕНИЮ ПЕРВИЧНЫХ ПАЦИЕНТОВ С СИМПТОМАМИ ДИСПЕПСИИ
Aim: To develop evidence-based recommendations for primary care physicians and general practitioners (GP) on choosing the proper management tactics and making valuable & quick diagnostic decisions at outpatient phase for patients with symptoms of dyspepsia, and also reveal possible oncology on time. Summary of recommendations: Approximately 40% of the patients in Russia presenting to primary care with symptoms of dyspepsia. A doctor has to focus on the warning signs, which may require an urgent additional examination & the consultation with a surgeon/onco-surgeon or other specialists if required. With regard to a risk of cancer, a doctor should be more cautious in patients over 45 years of age. Early diagnosis of oncology depends mainly on cautiousness of GP, primary care physicians and their knowledge, future tactics with regard to the patients. From the mandatory diagnostic tests during the first visit, esophagogastroduodenoscopy and H. pylori diagnostics helps to exclude any organic esophagus and stomach pathology, possible oncology. While waiting for endoscopy results, a physician should use the preliminary diagnoses “Uninvestigated Dyspepsia” (ICD-10 К 31.9) (disease of stomach and duodenum, unspecified). After exclusion of all warning signs, therapy of dyspepsia should be in accordance to the order of the Ministry of Health No 248 which gives an option to use proton pump inhibitors (omeprazole or rabeprazole 20 mg daily) in combination with prokinetic (domperidone 30 mg daily). Fixed drug combination of omeprazole 20 mg and modified-release domperidone 30 mg/daily (Omez® DSR) is medically reasonable. Conclusion: The introduction of this recommendation into clinical practice will help clinicians to prevent diagnostic mistakes, unreasonable use of expensive diagnostic examinations and inappropriate treatment leads to improvement in the overall prognosis and quality of life for the patients.Цель. Представить рекомендации диагностики и лечения пациентов с симптомами диспепсии на этапе амбулаторно-поликлинической помощи, обобщающие зарубежный и отечественный опыт ведения данной категории больных. Основная цель рекомендаций - помочь терапевту и врачу общей практики (ВОП) на амбулаторном этапе принять правильное решение о тактике ведения больного, и в максимально короткий срок поставить правильный диагноз, а также вовремя выявить у пациента наличие онкологической патологии. Основные положения. Около 40% обращений пациентов на амбулаторно-поликлиническом приеме в России связано с симптомами диспепсии. Врач, в первую очередь, должен исключить наличие «тревожных признаков», которые требуют незамедлительного дополнительного обследования пациента, привлечения хирурга и/или других специалистов и госпитализации больного. Доктор должен иметь онкологическую настороженность, особенно, при обращении пациентов в возрасте 45 лет и старше, так как ранняя диагностика злокачественных новообразований (ЗНО) зависит главным образом от онкологической настороженности терапевтов, врачей общей практики и их знаний, дальнейшей тактики в отношении больного. Эзофагогастродуоденоскопия и тесты на H. pylori являются обязательными методами исследования на этапе диагностического поиска и позволяют исключить органические заболевания пищевода и желудка, наличие онкологии. До получения результатов эндоскопического исследования следует выставлять предварительный диагноз «Диспепсия Неуточненная» и шифровать под рубрикой МКБ-10 К 31.9 (болезнь желудка и двенадцатиперстной кишки неуточненная). После исключения «тревожных признаков» терапия диспепсии проводится согласно Приказу МЗ РФ № 248 и включает назначение ингибиторов протонной помпы (омепразол или рабепразол 20 мг/сут) в комбинации с прокинетиком (домперидон 30 мг/сут). Оправдано применение фиксированной комбинации омепразола 20 мг с домперидоном модифицированного высвобождения 30 мг/сут (Омез® ДСР). Заключение. Внедрение рекомендаций в клиническую практику поможет врачу избежать ошибок при постановке диагноза, применения необоснованных и нередко дорогостоящих методов обследования, нерационального лечения, что позволит улучшить прогноз и качество жизни пациентов