Full mouth crown lengthening: a case report

Aims and objectives: Crown lengthening is a surgical procedure which aims at removal of periodontal tissue to increase the clinical crown height and reestablishing the biologic width. It is procedure which helps to meet both restorative and aesthetic demands of the patient.Case description: A female patient presented with a chief complaint of generalized worn out teeth. On examination collapsed bite with reduced vertical dimensions was observed, for which prosthetic rehabilitation was not possible so full moth crown lengthening was selected as the treatment modality.Conclusion: This case report demonstrated that surgical crown lengthening technique improved the vertical dimension of the patient  and also helped to reestablish the biologic width

Antileukemic Potential of Momordica charantia Seed Extracts on Human Myeloid Leukemic HL60 Cells

Momordica charantia (bitter gourd) has been used in the traditional system of medicine for the treatment of various diseases. Anticancer activity of M. charantia extracts has been demonstrated by numerous in vitro and in vivo studies. In the present study, we investigated the differentiation inducing potential of fractionated M. charantia seed extracts in human myeloid HL60 cells. We found that the HL60 cells treated with the fractionated seed extracts differentiated into granulocytic lineage as characterized by NBT staining, CD11b expression, and specific esterase activity. The differentiation inducing principle was found to be heat-stable, and organic in nature. The differentiation was accompanied by a downregulation of c-myc transcript, indicating the involvement of c-myc pathway, at least in part, in differentiation. Taken together these results indicate that fractionated extracts of M. charantia seeds possess differentiation inducing activity and therefore can be evaluated for their potential use in differentiation therapy for leukemia in combination with other inducers of differentiation

Comparative Clinical Evaluation of Yogic Practices and Apamarga Tandula (Seeds) along with their Additive Effect in Sthaulya (Obesity)

Background: In Indian classical text of Ayurveda and Yoga, there has been many indication given for sthaulya. After literature review, the Apamarga tandula and yogic practices were found as medohar (anti-obesity) agents.Objective: The present study was conducted to assess the individual as well as synergistic effect of yogic practices and Apamarga Tandula Ksheer-pak in Sthaulya.Materials and Methods: This study was carried out in Department of Dravyaguna, Sir Sundarlal Hospital, I.M.S., B.H.U., Varanasi. 160 patients of obesity were randomized into four groups, group-I (control), group-II (yogic practices daily for 1 hour), group-III (Apamarga Tandula Ksheer-pak treatment group) and in group-IV (yogic practiced daily for 1 hour along with Apamarga Tandula Ksheer-pak treatment). All the groups were followed up for 3 months. BMI and lipid profile of the groups were compared at the end of 3 months with SPSS tool (version 16).Results: Analysis of data after treatment of 3 months in all three groups (II, III, IV) of the study showed significant decrease in weight, BMI, total cholesterol, triglycerides and LDL, VLDL along with significant improvement in HDL.Conclusion: At last the trial group-IV exhibits more therapeutic efficiency over group-II and III

Cassava storage : post-harvest deterioration and storage of fresh cassava roots

<p>Sum of squares of the errors (SSE) between data from patients <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0014531#pone.0014531-Shankarappa1" target="_blank">[36]</a> and our predictions of viral diversity, <i>d_G</i>, and divergence, <i>d_S</i>, for different values of the population size, <i>C</i>, (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0014531#pone-0014531-g005" target="_blank">Fig. 5</a>) and the viral generation time, τ, shown for each of the nine patients. <i>C</i> and τ that yield the lowest SSE provide the best fit to the data. The best-fit value of <i>C</i> yields <i>N_e</i> (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0014531#pone-0014531-t001" target="_blank">Table 1</a>).</p

Solar Photovoltaic Principles

Due to the limited supply of fossil fuels in the modern era, humankind’s need for new energy sources is of utmost importance. Consequently, solar energy is essential to society. Solar energy is an endless and pure source of energy. Solar energy research is being used to help solve the world’s energy dilemma, safeguard the environment, and promote significant sustainable economic growth. Humans have now constructed numerous solar photovoltaic power plants to produce electricity, and many people have installed solar panels on their homes’ roofs to do the same. The non-mathematical explanation of PV solar cell theory and its circuit architecture is covered in this chapter. It is written for a variety of groups, including engineers who need an introduction to the subject of photovoltaic cells, end users who require a deeper understanding of the theory to support their applications, students interested in PV science and technology, and others. The fundamentals of the individual electricity-producing solar cell—the photovoltaic cell—are discussed in this chapter. The reader is informed about the workings of PV cells. The chapter focuses on the operation and construction of PV cells. The advantages and disadvantages of the cell’s potential industrial applications are discussed. Here, we go over how to ensure that the PV cells used in contemporary renewable energy systems are up to snuff

Comprehensive Evaluation of Anti-hyperglycemic Activity of Fractionated Momordica charantia

The present study evaluates anti-hyperglycemic activity of fractionated Momordica charantia (bitter gourd) seed extracts. Fasting blood glucose levels were evaluated before and after administration of different fractions of the seed extract. Among the three fractions tested, fraction Mc-3 (15 mg/kg b.wt.) showed the maximum anti-hyperglycemic activity and reduced blood glucose levels in experimental diabetic rats significantly. The activities of the key regulatory enzymes of glucose metabolism (hexokinase, pyruvate kinase, lactate dehydrogenase, and glucose-6-phosphate dehydrogenase) were determined in Mc-3-treated diabetic animals. Once-daily administration of the fraction Mc-3 for prolonged period of 18 days to the experimental diabetic animals did not result in any nephrotoxicity or hepatotoxicity as evident from insignificant changes in biochemical parameters indicative of liver and kidney functions. Further fractionation of the fraction Mc-3 by size exclusion chromatography resulted in a fraction, designated Mc-3.2, possessing anti-hyperglycemic activity. The fraction Mc-3.2 showed the presence of a predominant protein band of ~11 kDa on SDS-PAGE. Loss in anti-hyperglycemic activity of the Mc-3.2 upon protease treatment indicates the proteinaceous nature of the anti-hyperglycemic principles. Overall, the results suggest that Momordica charantia seeds contain an effective anti-hyperglycemic protein(s) which may find application in treatment of diabetes without evident toxic effects