The origin of mafic–ultramafic rocks and felsic plutons along the Clarke River suture zone: implications for porphyry exploration in the northern Tasmanides

The Clarke River Fault in northeast Queensland records an early Paleozoic history of subduction, accretion and continental suturing. Samples of mafic–ultramafic rocks collected proximal to the Clarke River Fault record oceanic geochemical affinities and comprise alteration assemblages consistent with an ophiolitic origin. The ca 456 Ma Falls Creek Tonalite records a continental-arc geochemical signature and was formed in response to long-lived subduction beneath the Thomson Orogen. Ordovician subduction beneath the Thomson Orogen is broadly coeval with arc magmatism documented in the Lachlan Orogen, which has been associated with the formation of several large porphyry ore deposits. The Falls Creek Tonalite yields adakite-like geochemical signatures that reflect a fertile melt source conducive to the formation of porphyry ore deposits. The outcropping plutons record ductile deformation consistent with mid-crustal depths, and they were emplaced during late syntectonic activity. This implies that the Falls Creek Tonalite was emplaced at too great a depth to have formed porphyry ore deposits. The northern Charters Towers Province shares many geological similarities to the Greenvale Province, where the erosional level may be shallower, and the potential for porphyry deposit formation and preservation may be greater

Schaffenrathʼs Inscription Column in Pisani rov, Postojnska jama

Napisi lahko pripomorejo k razjasnitvi nezadostno dokumentirane zgodovine odkrivanja glavnih rovov Postojnske jame. Ta čas je bil povezan s tremi osebami: Josipom Jeršinovičem plemenitim Löwengreif, Alojzom Schaffenrathom in grofom Francem Hohenwartom. Temelječ na sodobnih zapisih Schaffenratha (1834), Hohenwarta (1830, 1832a,b) in Schmidla (1854), avtorji razpravljajo o okoliščinah in času njihovih raziskovanj glavne jame ter menijo, da ta ni bila odkrita do prihoda nadvojvode Ferdinanda avgusta 1819. Eden najstarejših napisov iz tega časa je na kapniškem stebru v Pisanem rovu, 90 m od tam, kjer se odcepi od glavnega rova. Tu je Schaffenrath 1825 zapisal imeni Löwengreifa, Gospodaritscha in svoje. Ta steber je morda edino mesto v Postojnski jami, kjer so vsa tri imena skupaj. Če upoštevamo razmeroma pozne raziskave glavnega rova, je letnica 1825 morda leto odkritja tega dela jame. To potrjuje tudi dejstvo, da tega dela jame ni na prvem objavljenem zemljevidu (Bronn, 1826, temelječ na zemljevidu Foÿker/Schaffenrath iz okoli 1821). 1832 je bil odprt notranji del Pisanega rova in imenovan v čast nadvojvode Janeza. Na steber so dodali še več napisov, več pa jih je tudi dalje po rovu. Iz 1836 je podpis J(ozef) Hauer, to je paleontolog in oče Franca plemenitega Hauerja. Tudi Anton Perko, mlajši brat Ivana Andreja, je zapustil svoje ime. I.A. Perko je podpisan 1892 v Rovu brez imena, v letu preden so on, njegov brat in drugi v Trstu ustanovili študentsko jamarsko društvo “Hades”. Raziskovanje in dokumentiranje zgodovinskih napisov lahko pomaga pri rekonstrukciji in razlagi zgodovine raziskav in odkrivanj te najpomembnejše turistične jame.Inscriptions may help to clarify the incompletely documented early history of the discovery of the main passages in Postojnska jama. This period is associated with three people: Josef (Josip) Jeršinovič Ritter von Löwengreif, Alois Schaffenrath, and Franz Graf von Hohenwart. Based on the contemporary writings of Schaffenrath (1834), Hohenwart (1830, 1832a,b) and Schmidl (1854) the authors discuss the circumstances and timing of the exploration of the main cave, suggesting that the main passage was not discovered until after the visit of Erzherzog Ferdinand in August 1819. One of the earliest inscriptions from that period is found on a column in Pisani rov, 90 m from its branch from the main passage. Here Schaffenrath left in 1825 the names of Löwengreif, of Gospodaritsch, and of himself. This column may be the only site in Postojnska jama featuring all three names in one place. In view of the rather late exploration of the main passage, the date 1825 may be the discovery date of this section of the cave since it does not appear on the earliest map published (Bronn, 1826, based on a map of Foÿker/Schaffenrath ca. 1821). In 1832 the back part of Pisani rov was opened and named in honour of Erzherzog Johann. Several more inscriptions were placed on the column. Further down the passage a few more inscriptions exist. One was dated 1836 by J(ozef) Hauer, a paleontologist and the father of Franz Ritter von Hauer. Also Anton Perko, the younger brother of Ivan Andrej Perko left his name. I.A. Perko signed as well, but in the Rov brez imena, in the year 1892, a year before he, his brother and others founded the student caversʼ club “Hades” in Trieste. Search and documentation of historic inscriptions may therefore aid in reconstructing the exploration and visitation history of this most important show cave

Cu isotopes in groundwater for hydrogeochemical mineral exploration: A case study using the world-class Mount Isa Cu–Pb–Zn deposit (Australia)

Copper is the crux resource in the transition to renewable energy sources, with green technologies such as solar panels, wind turbines and batteries all relying on this critical metal for their componentry, and more importantly for connection to electrical grids. While demand intensifies, copper discovery rates continue to fall due to increased scarcity of deposits that are outcropping and/or detectable by conventional means. This has engendered novel methods of detecting Cu-bearing ore under cover, such as hydrogeochemical analyses to trace ore mineral interaction with natural waters. This notably includes the development of Cu isotope systematics in natural waters, wherein proximal to Cu-bearing ore bodies enrichment of water in the heavier Cu isotope occurs (e.g. from oxidative weathering), thus providing a fingerprint of water interaction with Cu-bearing sulfides. Here, Cu isotope compositions for eighteen groundwater samples overlying and distal to the world-class, sediment-hosted stratiform Mount Isa Cu–Zn–Pb deposit were analyzed to assess the utility of groundwater Cu isotope compositions as an exploration tool for Cu-bearing ore under cover. A further 12 chalcopyrite Cu isotope compositions were determined from two drill cores directly overlying the main Cu-bearing ore body, to establish a baseline Cu isotope composition for the Mt Isa deposit. Cu isotope data were synthesized together with field water parameters and placed within a geological context to construct a framework for interpretation. When accounting for industrially impacted sites and underlying geology, results show a clear trend towards heavy Cu isotope enrichment in groundwater proximal to known mineralization, with enrichments of ∼1 per mil (‰) or more relative to distal groundwater and primary deposit chalcopyrite. These results corroborate and expand upon similar work from surface and groundwater samples around porphyry, exotic and IOCG Cu-bearing deposits. Moreover, these results strongly indicate that groundwater Cu isotope systematics for exploration under cover has great potential as a vectoring tool, illustrating that thus far the technique is applicable across deposit types

Amino acid residues that are important for Hyal2 function as a receptor for jaagsiekte sheep retrovirus

BACKGROUND: Infection by jaagsiekte sheep retrovirus (JSRV) and by enzootic nasal tumor virus (ENTV) depends on cell-surface expression of the virus entry receptor, hyaluronidase 2 (Hyal2). Human Hyal2 binds the envelope (Env) proteins of these viruses and is functional as a receptor, but Hyal2 from mice does not bind Env nor does it mediate entry of either virus. Here we have explored the amino acid determinants that account for the difference in receptor function. RESULTS: Analysis of human-mouse Hyal2 chimeric proteins showed that amino acid differences responsible for the difference in Hyal2 receptor activity were localized to the central third of Hyal2. Human Hyal2 mutants containing single or double amino acid replacements with the respective mouse amino acids were generated across this region and were assayed for activity. None of the single or double mutation reduced the receptor activity of human Hyal2 by more than 10-fold, whereas mouse Hyal2 activity is reduced 1,000-fold from that of human Hyal2. While the 3-dimensional structures of mammalian Hyal2 proteins are unknown, bee venom hyaluronidase shows significant amino acid similarity to human and mouse Hyal2 and its structure has been determined. Many mutations having the largest negative effects on human Hyal2 function mapped to a small region of the bee venom hyaluronidase close to but not overlapping the active site of the enzyme, suggesting that this site represents the binding site for Env. Analysis of synonymous and non-synonymous nucleotide substitutions in the coding sequences of multiple mammalian Hyal2 proteins shows that the proteins are undergoing strong selection for amino acid conservation. We found no evidence for positive selection of amino acid changes that might reflect evolution of mammalian hosts to resist JSRV or ENTV infection. CONCLUSION: These results show that the greatly reduced receptor activity of mouse Hyal2 in comparison to that of human Hyal2 is determined by multiple amino acid changes acting in concert. In particular, no one amino acid change blocks infection. However, the most important amino acids map to a small patch on a predicted 3-dimensional Hyal2 structure, which may represent the binding site for Env

Blood product ratio in acute traumatic coagulopathy - effect on mortality in a Scandinavian level 1 trauma centre

BACKGROUND: Trauma is the leading cause of loss of life expectancy worldwide. In the most seriously injured patients, coagulopathy is often present on admission. Therefore, transfusion strategies to increase the ratio of plasma (FFP) and platelets (PLT) to red blood cells (RBC), simulating whole blood, have been introduced. Several studies report that higher ratios improve survival in massively bleeding patients. Here, the aim was to investigate the potential effect of increased FFP and PLT to RBC on mortality in trauma patients. METHODS: In a retrospective before and after study, all trauma patients primarily admitted to a level-one Trauma Centre, receiving blood transfusion, in 2001-3 (n = 97) and 2005-7 (n = 156), were included. In 2001-3, FFP and PLT were administered in accordance with the American Society of Anesthesiologists (ASA) guidelines whereas in 2005-7, Hemostatic Control Resuscitation (HCR) entailing pre-emptive use of FFP and PLT in transfusion packages during uncontrolled haemorrhage and thereafter guided by thrombelastograph (TEG) analysis was employed. The effect of transfusion therapy and coagulopathy on mortality was investigated. RESULTS: Patients included in the early and late period had comparable demography, injury severity score (ISS), admission hematology and coagulopathy (27% vs. 34% had APTT above normal). There was a significant change in blood transfusion practice with shorter time interval from admission to first transfusion (median time 3 min vs.28 min in massive bleeders, p < 0.001), transfusion of higher ratios of FFP:RBC, PLT:RBC and PLT:FFP in the HCR group but 30-day mortality remained comparable in the two periods. In the 2005-7 period, higher age, ISS and Activated Partial Thromboplastin Time (APTT) above normal were independent predictors of mortality whereas no association was fund between blood product ratios and mortality. CONCLUSION: Aggressive administration of FFP and PLT did not influence mortality in the present trauma population

EFSUMB Recommendations and Guidelines for Gastrointestinal Ultrasound - Part 1: Examination Techniques and Normal Findings (Short version)

Abstract ▼ In October 2014 the European Federation of Societies for Ultrasound in Medicine and Biology formed a Gastrointestinal Ultrasound (GIUS) task force group to promote the use of GIUS in a clinical setting. One of the main objectives of the task force group was to develop clinical recommendations and guidelines for the use of GIUS under the auspices of EFSUMB. The first part, gives an overview of the examination techniques for GIUS recommended by experts in the field. It also presents the current evidence for the interpretation of normal sonoanatomical and physiological features as examined with different ultrasound modalities

EFSUMB Recommendations and Guidelines for Gastrointestinal Ultrasound - Part 1: Examination Techniques and Normal Findings (Long version).

Abstract ▼ In October 2014 the European Federation of Societies for Ultrasound in Medicine and Biology formed a Gastrointestinal Ultrasound (GIUS) task force group to promote the use of GIUS in a clinical setting. One of the main objectives of the task force group was to develop clinical recommendations and guidelines for the use of GIUS under the auspices of EFSUMB. The first part, gives an overview of the examination techniques for GIUS recommended by experts in the field. It also presents the current evidence for the interpretation of normal sonoanatomical and physiological features as examined with different ultrasound modalities

Getting residents closer to public institutions through gamification

With the huge growth of mobile device users, in recent years, the need and the opportunity to create new digital services and platforms has arisen. These platforms and services not only make people’s daily life easier, but also facilitate and improve communication between institutions and people. Also, new ways of achieving the intended goals are being developed and tested. Gamification is an example, where institutions and people’s communication is encouraged through the offering of incentives/rewards that potentiate involvement with that particular institution. In practice, institutions offer rewards to participants who perform predetermined tasks, for recommendation, dissemination, evaluation or greater involvement of people with that particular institution. The concept of smart cities is also getting huge attention nowadays. Making a city “smart” is emerging as a strategy to mitigate the problems generated by the urban population growth and rapid urbanization. In this work, we propose a digital solution, in the form of a mobile application, which has as its main goal to improve city hall public services and people’s communication, bringing them closer. This is achieved using gamification techniques that aim to engage residents with city hall services. It is provided a report system that enables residents to communicate to the city hall services, some issues regarding their town that they wish to be solved, such as broken structures, clogged sewers, among others. The proposed system also has a lore that leads to extra motivation to complete missions, be part of player gatherings and events, and meet new people and to better explore the cities’ wonders. An admin platform for the maintenance and administration of the system is also proposed, to better help keeping the application’s content fresh and updated, allowing for a better user experience for the population. The proposed system is being prepared for testing in real environments, the simulation results, as showed in tThis work has been supported by COMPETE: POCI-01-0145-FEDER-007043 and FCT –Fundação para a Ciência e Tecnologia within the Project Scope: UID/CEC/00319/201

The structural history and mineralization controls of the world-class Geita Hill gold deposit, Geita Greenstone Belt, Tanzania

The Geita Hill gold deposit is located in the Archean Geita Greenstone Belt and is one of the largest gold deposits in East Africa. The Geita Greenstone Belt experienced a complex deformation and intrusive history that is well illustrated and preserved in and around the Geita Hill gold deposit. Deformation involved early stages of ductile shearing and folding (D1 to D5), during which episodic emplacement of large diorite intrusive complexes, sills, and dykes occurred. These ductile deformation phases were followed by the development of brittle-ductile shear zones and faults (D6 to D8). The last stages of deformation were accompanied by voluminous felsic magmatism involving the intrusion of felsic porphyry dykes, within the greenstone belt, and the emplacement of large granitic bodies now forming the margins of the greenstone belt. Early, folded lamprophyre dykes, and later lamprophyre dykes, crosscutting the folded sequence are common, although volumetrically insignificant. The gold deposit formed late during the tectonic history of the greenstone belt, post-dating ductile deformation and synchronous with the development of brittle-ductile shear zones that overprinted earlier structural elements. The main mineralizing process involved sulfide replacement of magnetite-rich layers in ironstone and locally the replacement of ferromagnesian phases and magnetite in the diorite intrusions. The intersection between the brittle-ductile (D6) Geita Hill Shear Zone and different structural elements of ductile origin (e.g., fold hinges), and the contact between banded ironstone and folded diorite dykes and sills provided the optimal sites for gold mineralization

Zircon U-Pb ages and Hf isotope data from the Kukuluma Terrain of the Geita Greenstone Belt, Tanzania Craton: Implications for stratigraphy, crustal growth and timing of gold mineralization

The Geita Greenstone Belt is a late Archean greenstone belt located in the Tanzania Craton, trending approximately E-Wand can be subdivided into three NW-SE trending terrains: the Kukuluma Terrain to the east, the Central Terrain in the middle and the Nyamullilima Terrain in the west. The Kukuluma Terrain, forms a NW-SE trending zone of complexly deformed sediments, intruded by the Kukuluma Intrusive Complex which, contains an early-syntectonic diorite-monzonite suite and a late-syntectonic granodiorite suite. Three gold deposits (Matandani, Kukuluma and Area 3W) are found along the contact between the Kukuluma Intrusive Complex and the sediments. A crystal tuff layer from the Kukuluma deposits returned an age of 2717 ± 12 Ma which can be used to constrain maximum sedimentation age in the area. Two granodiorite dykes from the same deposit and a small granodiorite intrusion found along a road cut yielded zircon ages of 2667 ± 17 Ma, 2661 ± 16 Ma and 2663 ± 11 Ma respectively. One mineralized granodiorite dyke from the Matandani deposit has an age of 2651 ± 14 Ma which can be used to constrain the maximum age of the gold mineralization in the area. The 2717 Ma crystal tuff has zircon grains with suprachondritic 176Hf/177Hf ratios (0.28108e0.28111 at 2717 Ma) and positive (þ1.6 to þ2.6) εHf values indicating derivation from juvenile mafic crust. Two of the granodiorite samples have suprachondritic 176Hf/177Hf ratios (avg. 0.28106 and 0.28107 at 2663 and 2651 Ma respectively) and nearly chondritic εHf values (avg. -0.5 and -0.3 respectively). The other two granodiorite samples have chondritic 176Hf/177Hf ratios (avg. 0.28104 and 0.28103 at 2667 and 2661 Ma respectively) and slightly negative εHf values (avg. -1.1 and -1.5 respectively). The new zircon age and isotope data suggest that the igneous activity in the Kukuluma Terrain involves a significant juvenile component and occurred within the 2720 to 2620 Ma period which, is the main period of crustal growth in the northern half of the Tanzania Craton