The Knowledge Society at Crossroads: The Road Map and Incubating Role of the Competitive Intelligence, Digitalization and Neurosciences

The today human being is part of the technological and scientific development dominated by information as a both raw material and base of knowledge. The easy and open accesses to information thrust forward the frontiers of development and communication, enlarge the development\u27s paths and generate amazing changes, faster than ever happened. The way that data bases increase its volume becomes the most actual and complex problem. The ability to extract and process the knowledge and the speed of its processing represent unknown and provocative challenges for business profit and the intelligent society success. Their extraction from the informational noise and the ability to react and rapidly communicate are also important to be accurately customized and harmonised with the social elements. This paper demonstrates the usefulness of neuroscience, neuro-technologies and cognitive computing in finding innovative and customized solutions for solving complex problems in business. The conclusion of our study is that, in order to have an advanced and competitive European Union, it is absolutely necessary to develop innovative solutions for Competitive Intelligence that would include the fundamental elements of neuro-technologies and advanced Artificial Intelligence as Cognitive Business profitable keys

THE KNOWLEDGE SOCIETY AT CROSSROADS: THE ROAD MAP AND INCUBATING ROLE OF THE COMPETITIVE INTELLIGENCE, DIGITALISATION AND NEUROSCIENCES

The today human being is part of the technological and scientific development dominated by information as a both raw material and base of knowledge.The easy and open accesses to information thrust forward the frontiers of development and communication, enlarge the development's paths and generate amazing changes, faster than ever happened. The way that data bases increase its volume becomes the most actual and complex problem.The ability to extract and process the knowledge and the speed of its processing represent unknown and provocative challenges for business profit and the intelligent society success. Their extraction from the informational noise and the ability to react and rapidly communicate are also important to be accurately customized and harmonised with the social elements.This paper demonstrates the usefulness of neuroscience, neuro-technologies and cognitive computing in finding innovative and customized solutions for solving complex problems in business.The conclusion of our study is that, in order to have an advanced and competitive European Union, it is absolutely necessary to develop innovative solutions for Competitive Intelligence that would include the fundamental elements of neuro-technologies and advanced Artificial Intelligence as Cognitive Business profitable keys

Competitive Intelligence and Neuro-Technologies: The New Strategic Tools to Boost The Digital Economy

Purpose – This paper aims to bridge the conceptual gap between the competitive intelligence domain and the current digital transformation and adaptation to the new values, norms, requests and expectations of Industry 4.0. Starting with the theoretical and chronological background attributed to the current developments, the following pages proceed to developing the argument that the Competitive Intelligence domain has become an imperative for the whole process of decision-making involved in Industry 4.0, applied to all businesses, disregard their status, domain, or turnover. Design/methodology/approach – Adopting a multidisciplinary perspective, the paper uses both a theoretical and practical approach to the main concepts involved: Competitive Intelligence, neuro-technologies, Industry 4.0. While defining those central concepts and presenting the chronological evolution of the economic domain, it also provides examples of key tools and their application in the current Digital Era. Findings – The current times are marked by a process of transition from digital transformation to digitization in almost all global businesses. The transition to digitalization affects the entire organizational ecosystem by integrating with digital solutions the value chain of global business. While the paper limits itself to setting the stage for future research, it still provides a valid range of theoretical knowledge and pragmatic applicability of the discussed concepts in the context of the current developing global reality. Originality/value – Beyond the theoretical and chronological analysis, a valuable content of this paper is the discussion of innovative tools within the domain of competitive intelligence and neuro-technologies to enhance the adaptability to rapidly changing conditions, the agility in decision-making and the flexibility to redesign the existing strategies based on pertinent analysis of a great influx of informatio

Competitive Intelligence and Academic Entrepreneurship as Innovative Vectors of a Resilient, Business-Oriented Education

Purpose – The present paper substantiates that the concepts of competitive intelligence and academic entrepreneurship are genuinely connected to the modern society and, through their perpetual and versatile evolution, have an important role in moving the development on the right way. Design/methodology/approach – Their evolutive is completed by a comparative analysis as appropriate method to point out similarities and differences and identify the way their application may serve innovation as a tool for those activating in the related domains of education, within our highly dynamic world. Findings – The development of the concepts is meant to link and accelerate the technological and operational innovation to a highly competitive academic environment, business-oriented, as a contribution to its wide potential for profit. Originality/value – The correlation between the two concepts provides an innovative tool able to serve as a platform helping the competitive intelligence, as design and functions, for any academic entrepreneurship business-oriented

The effects of tryptophan loading on Attention Deficit Hyperactivity in adults:A remote double blind randomised controlled trial

BackgroundDespite the impact and prevalence of Attention Deficit Hyperactivity Disorder (ADHD), current treatment options remain limited and there is a drive for alternative approaches, including those building on evidence of a role for tryptophan (TRP) and serotonin (5-HT). This study aimed to evaluate the effect of acute TRP loading on attention and impulsivity in adults with ADHD.Trial design and methods We conducted a remote double blind randomised controlled trial (RCT) using TRP loading to examine the effects of a balanced amino acid load in comparison to low and high TRP loading in individuals with ADHD (medicated, N = 48, and unmedicated, N = 46) and controls (N = 50). Participants were randomised into one of three TRP treatment groups using stratified randomisation considering participant group and gender using a 1:1:1 ratio. Baseline testing of attention and impulsivity using the Test of Variables of Attention Task, Delay Discounting Task, and Iowa Gambling Task was followed by consumption of a protein drink (BAL, LOW, or HIGH TRP) before repeated testing. Results and ConclusionsNo effects of TRP were observed for any of the measures. In the present study, TRP loading did not impact on any measure of attention or impulsivity in those with ADHD or Controls. The findings need to be confirmed in another trial with a larger number of patients that also considers additional measures of dietary protein, plasma TRP and aggression. (Registration ID ISRCTN15119603)<br/

Effects of captions, transcripts and reminders on learning and perceptions of lecture capture: A mixed-methods case study

Lecture capture is popular within Higher Education, but previous research suggests that students do not always optimally select content to review, nor do they make the most of specific functions. In the current study conducted in the 2019/20 academic year, we used a repeated-measures crossover design to establish the effects of transcripts with closed captioning, and email reminders, on use (self-reported and system analytics), perceptions of lecture capture and student performance, as measured by multiple-choice question (MCQ) tests designed to assess the module learning outcomes. System analytics (N = 129) and survey data (N = 42) were collected from students alongside qualitative data from semi-structured interviews (N = 8). We found that students value lecture capture highly, but do not access it extensively during the teaching period. The availability of transcripts and closed captions did not impact the amount of capture use or performance on MCQ tests, but did result in more positive perceptions of capture, including increased likelihood of recommending it to others. The use of email reminders referring students to specific segments of capture and reminding them of the functionality had no impact on any measure, although qualitative data suggested that the content of reminders may be used in revision rather than during the teaching period, which fell outside the period we investigated. Collectively, these data suggest that the use of captions and transcripts may be beneficial to students by allowing dual processing of visual and audio content, and a searchable resource to help consolidate their learning but there is little evidence to support reminders

The effects of different exercise approaches on Attention Deficit Hyperactivity in adults: a randomised controlled trial

Attention Deficit Hyperactivity Disorder results in significant functional impairment and current treatments, particularly for adults are limited. Previous research indicates that exercise may offer an alternative approach to managing ADHD but research into different types of exercise and adult populations is limited. The aim of this study was to examine the effects of acute exercise (aerobic cycling vs mind-body yoga exercises) on symptoms of ADHD in adults. Adults with ADHD (N=82) and controls (N=77) were randomly allocated to 10 minutes of aerobic (cycling) or mind-body (Hatha yoga) exercise. Immediately before and after exercise, participants completed the Test of Variables of Attention Task, Delay Discounting Task, and Iowa Gambling Task to measure attention and impulsivity. Actigraphy measured movement frequency and intensity. Both groups showed improved temporal impulsivity post-exercise, with cycling beneficial to all, whilst yoga only benefited those with ADHD. There were no effects of exercise on attention, cognitive or motor impulsivity, or movement in those with ADHD. Exercise reduced attention and increased movement in controls. Exercise can improve temporal impulsivity in adult ADHD but did not improve other symptoms and worsened some aspects of performance in controls. Exercise interventions should be further investigate

Do engagement and behavioural mechanisms underpin the effectiveness of the Drink Less app?

This is a process evaluation of a large UK-based randomised controlled trial (RCT) (n = 5602) evaluating the effectiveness of recommending an alcohol reduction app, Drink Less, compared with usual digital care in reducing alcohol consumption in increasing and higher risk drinkers. The aim was to understand whether participants’ engagement (‘self-reported adherence’) and behavioural characteristics were mechanisms of action underpinning the effectiveness of Drink Less. Self-reported adherence with both digital tools was over 70% (Drink Less: 78.0%, 95% CI = 77.6–78.4; usual digital care: 71.5%, 95% CI = 71.0–71.9). Self-reported adherence to the intervention (average causal mediation effect [ACME] = −0.250, 95% CI = −0.42, −0.11) and self-monitoring behaviour (ACME = −0.235, 95% CI = −0.44, −0.03) both partially mediated the effect of the intervention (versus comparator) on alcohol reduction. Following the recommendation (self-reported adherence) and the tracking (self-monitoring behaviour) feature of the Drink Less app appear to be important mechanisms of action for alcohol reduction among increasing and higher risk drinkers

Clinical complexity and impact of the ABC (Atrial fibrillation Better Care) pathway in patients with atrial fibrillation: a report from the ESC-EHRA EURObservational Research Programme in AF General Long-Term Registry

Background: Clinical complexity is increasingly prevalent among patients with atrial fibrillation (AF). The ‘Atrial fibrillation Better Care’ (ABC) pathway approach has been proposed to streamline a more holistic and integrated approach to AF care; however, there are limited data on its usefulness among clinically complex patients. We aim to determine the impact of ABC pathway in a contemporary cohort of clinically complex AF patients. Methods: From the ESC-EHRA EORP-AF General Long-Term Registry, we analysed clinically complex AF patients, defined as the presence of frailty, multimorbidity and/or polypharmacy. A K-medoids cluster analysis was performed to identify different groups of clinical complexity. The impact of an ABC-adherent approach on major outcomes was analysed through Cox-regression analyses and delay of event (DoE) analyses. Results: Among 9966 AF patients included, 8289 (83.1%) were clinically complex. Adherence to the ABC pathway in the clinically complex group reduced the risk of all-cause death (adjusted HR [aHR]: 0.72, 95%CI 0.58–0.91), major adverse cardiovascular events (MACEs; aHR: 0.68, 95%CI 0.52–0.87) and composite outcome (aHR: 0.70, 95%CI: 0.58–0.85). Adherence to the ABC pathway was associated with a significant reduction in the risk of death (aHR: 0.74, 95%CI 0.56–0.98) and composite outcome (aHR: 0.76, 95%CI 0.60–0.96) also in the high-complexity cluster; similar trends were observed for MACEs. In DoE analyses, an ABC-adherent approach resulted in significant gains in event-free survival for all the outcomes investigated in clinically complex patients. Based on absolute risk reduction at 1 year of follow-up, the number needed to treat for ABC pathway adherence was 24 for all-cause death, 31 for MACEs and 20 for the composite outcome. Conclusions: An ABC-adherent approach reduces the risk of major outcomes in clinically complex AF patients. Ensuring adherence to the ABC pathway is essential to improve clinical outcomes among clinically complex AF patients

Impact of renal impairment on atrial fibrillation: ESC-EHRA EORP-AF Long-Term General Registry

Background: Atrial fibrillation (AF) and renal impairment share a bidirectional relationship with important pathophysiological interactions. We evaluated the impact of renal impairment in a contemporary cohort of patients with AF. Methods: We utilised the ESC-EHRA EORP-AF Long-Term General Registry. Outcomes were analysed according to renal function by CKD-EPI equation. The primary endpoint was a composite of thromboembolism, major bleeding, acute coronary syndrome and all-cause death. Secondary endpoints were each of these separately including ischaemic stroke, haemorrhagic event, intracranial haemorrhage, cardiovascular death and hospital admission. Results: A total of 9306 patients were included. The distribution of patients with no, mild, moderate and severe renal impairment at baseline were 16.9%, 49.3%, 30% and 3.8%, respectively. AF patients with impaired renal function were older, more likely to be females, had worse cardiac imaging parameters and multiple comorbidities. Among patients with an indication for anticoagulation, prescription of these agents was reduced in those with severe renal impairment, p&nbsp;&lt;.001. Over 24&nbsp;months, impaired renal function was associated with significantly greater incidence of the primary composite outcome and all secondary outcomes. Multivariable Cox regression analysis demonstrated an inverse relationship between eGFR and the primary outcome (HR 1.07 [95% CI, 1.01–1.14] per 10&nbsp;ml/min/1.73&nbsp;m2 decrease), that was most notable in patients with eGFR &lt;30&nbsp;ml/min/1.73&nbsp;m2 (HR 2.21 [95% CI, 1.23–3.99] compared to eGFR ≥90&nbsp;ml/min/1.73&nbsp;m2). Conclusion: A significant proportion of patients with AF suffer from concomitant renal impairment which impacts their overall management. Furthermore, renal impairment is an independent predictor of major adverse events including thromboembolism, major bleeding, acute coronary syndrome and all-cause death in patients with AF