379 research outputs found
A new stability results for the backward heat equation
In this paper, we regularize the nonlinear inverse time heat problem in the
unbounded region by Fourier method. Some new convergence rates are obtained.
Meanwhile, some quite sharp error estimates between the approximate solution
and exact solution are provided. Especially, the optimal convergence of the
approximate solution at t = 0 is also proved. This work extends to many earlier
results in (f2,f3, hao1,Quan,tau1, tau2, Trong3,x1).Comment: 13 page
Random walks on mutual microRNA-target gene interaction network improve the prediction of disease-associated microRNAs
Background: MicroRNAs (miRNAs) have been shown to play an important role in pathological initiation, progression and maintenance. Because identification in the laboratory of disease-related miRNAs is not straightforward, numerous network-based methods have been developed to predict novel miRNAs in silico. Homogeneous networks (in which every node is a miRNA) based on the targets shared between miRNAs have been widely used to predict their role in disease phenotypes. Although such homogeneous networks can predict potential disease-associated miRNAs, they do not consider the roles of the target genes of the miRNAs. Here, we introduce a novel method based on a heterogeneous network that not only considers miRNAs but also the corresponding target genes in the network model. Results: Instead of constructing homogeneous miRNA networks, we built heterogeneous miRNA networks consisting of both miRNAs and their target genes, using databases of known miRNA-target gene interactions. In addition, as recent studies demonstrated reciprocal regulatory relations between miRNAs and their target genes, we considered these heterogeneous miRNA networks to be undirected, assuming mutual miRNA-target interactions. Next, we introduced a novel method (RWRMTN) operating on these mutual heterogeneous miRNA networks to rank candidate disease-related miRNAs using a random walk with restart (RWR) based algorithm. Using both known disease-associated miRNAs and their target genes as seed nodes, the method can identify additional miRNAs involved in the disease phenotype. Experiments indicated that RWRMTN outperformed two existing state-of-the-art methods: RWRMDA, a network-based method that also uses a RWR on homogeneous (rather than heterogeneous) miRNA networks, and RLSMDA, a machine learning-based method. Interestingly, we could relate this performance gain to the emergence of "disease modules" in the heterogeneous miRNA networks used as input for the algorithm. Moreover, we could demonstrate that RWRMTN is stable, performing well when using both experimentally validated and predicted miRNA-target gene interaction data for network construction. Finally, using RWRMTN, we identified 76 novel miRNAs associated with 23 disease phenotypes which were present in a recent database of known disease-miRNA associations. Conclusions: Summarizing, using random walks on mutual miRNA-target networks improves the prediction of novel disease-associated miRNAs because of the existence of "disease modules" in these networks
DEVELOPMENT AND APPLICATION OF THE ENVIRONMENTAL HYDRODYNAMIC 3D MODEL FOR COMPUTATION AND FORECASTING OF OIL POLLUTIONS IN COASTAL MARINE ENVIRONMENT
Joint Research on Environmental Science and Technology for the Eart
Benchmarking Jetson Edge Devices with an End-to-end Video-based Anomaly Detection System
Innovative enhancement in embedded system platforms, specifically hardware
accelerations, significantly influence the application of deep learning in
real-world scenarios. These innovations translate human labor efforts into
automated intelligent systems employed in various areas such as autonomous
driving, robotics, Internet-of-Things (IoT), and numerous other impactful
applications. NVIDIA's Jetson platform is one of the pioneers in offering
optimal performance regarding energy efficiency and throughput in the execution
of deep learning algorithms. Previously, most benchmarking analysis was based
on 2D images with a single deep learning model for each comparison result. In
this paper, we implement an end-to-end video-based crime-scene anomaly
detection system inputting from surveillance videos and the system is deployed
and completely operates on multiple Jetson edge devices (Nano, AGX Xavier, Orin
Nano). The comparison analysis includes the integration of Torch-TensorRT as a
software developer kit from NVIDIA for the model performance optimisation. The
system is built based on the PySlowfast open-source project from Facebook as
the coding template. The end-to-end system process comprises the videos from
camera, data preprocessing pipeline, feature extractor and the anomaly
detection. We provide the experience of an AI-based system deployment on
various Jetson Edge devices with Docker technology. Regarding anomaly
detectors, a weakly supervised video-based deep learning model called Robust
Temporal Feature Magnitude Learning (RTFM) is applied in the system. The
approach system reaches 47.56 frames per second (FPS) inference speed on a
Jetson edge device with only 3.11 GB RAM usage total. We also discover the
promising Jetson device that the AI system achieves 15% better performance than
the previous version of Jetson devices while consuming 50% less energy power.Comment: 18 pages, 7 figures, 5 table
Synthesis of ZnO nanorod for immunosensor application
This paper reported a facile method to synthesize ZnO nanorods for immunosensor application. The ZnO nanorods were synthesized by hydrothermal reaction. Synthesis time affecting on morphology of nanorods was also studied. The immobilization of anti-rotavirus onto ZnO nanorod-deposited sensor was performed via absorption method. The electrochemical responses of the immunosensor were studied by cyclic voltammetry (C-V) method with [Fe(CN)6]3−/4− as redox probe. A linear decreased response in C-V for cell of rotavirus concentration was found in the range of 7.8×105 CFU/mL to 7.8×108 CFU/mL. The detection limit of the immunosensor was 7.8×105 CFU/mL. The results indicated application of ZnO nanorod sensor for label-free real-time detection of a wide dynamics range of biological species
Corporate governance and firm performance: Evidence from Vietnamese listed companies
The research aims to provide empirical evidence on the relationship between corporate governance and firm performance in Vietnam – a developing economy in Asia. It focuses on the corporate governance of Vietnamese listed companies with a data-set of the five-year period from 2011 to 2015. Vietnamese listed companies are governed and controlled by two boards, Board of Directors and Supervisory Board. The research investigates the impacts of directors’ and supervisors’ characteristics and ownership structure on firm performance. The outcomes reveal that most governance mechanisms employed by Vietnamese listed companies were not effective and had no effect on the companies’ performance, except for managerial ownership and Supervisory Board size. Specifically, management ownership and firm performance were negatively correlated. Additional analyses show a positive relationship between the number of supervisors and firm performance, which was measured by market-based measurement
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