268 research outputs found
Impact of Credit Default Swaps on Firms’ Operational Efficiency
As one of the most important financial innovations in the last two decades, credit default swap (CDS) contracts have been initiated and actively traded in the market to hedge against credit risks. However, little is known about how these financial innovations affect an underlying firm’s operations. In this empirical study, we find that an underlying firm’s operational efficiency is significantly improved with the inception of CDS trading. Our results are robust to multiple causal identification strategies. Further analysis suggests that the inception of CDS tends to enhance the operational efficiency of a firm through the supply chain financing capability and trade credit. We also postulate that CDS leads to enhanced efficiency through institutional monitoring and improvements in management effectiveness. We then obtain suggestive evidence. Our findings have direct implications concerning the ongoing policy debate surrounding CDS. We contribute to operations management research by exploring how innovations in the financial market would, in turn, affect the operational performance of firms
GeneNarrator: Mining the Literaturome for Relations Among Genes
The rapid development of microarray and other genomic technologies now enables biologists to monitor the expression of hundreds, even thousands of genes in a single experiment. Interpreting the biological meaning of the expression patterns still relies largely on biologist\u27s domain knowledge, as well as on information collected from the literature and various public databases. Yet individual experts’ domain knowledge is insufficient for large data sets, and collecting and analyzing this information manually from the literature and/or public databases is tedious and time-consuming. Computer-aided functional analysis tools are therefore highly desirable. We describe the architecture of GeneNarrator, a text mining system for functional analysis of microarray data. This system’s primary purpose is to test the feasibility of a more general system architecture based on a two-stage clustering strategy that is explained in detail. Given a list of genes, GeneNarrator collects abstracts about them from PubMed, then clusters the abstracts into functional topics in a first clustering stage. In the second clustering stage, the genes are clustered into groups based on similarities in their distributions of occurrence across topics. This novel two-stage architecture, the primary contribution of this project, has benefits not easily provided by onestage clustering
Grounding Classical Task Planners via Vision-Language Models
Classical planning systems have shown great advances in utilizing rule-based
human knowledge to compute accurate plans for service robots, but they face
challenges due to the strong assumptions of perfect perception and action
executions. To tackle these challenges, one solution is to connect the symbolic
states and actions generated by classical planners to the robot's sensory
observations, thus closing the perception-action loop. This research proposes a
visually-grounded planning framework, named TPVQA, which leverages
Vision-Language Models (VLMs) to detect action failures and verify action
affordances towards enabling successful plan execution. Results from
quantitative experiments show that TPVQA surpasses competitive baselines from
previous studies in task completion rate
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A snoRNA modulates mRNA 3' end processing and regulates the expression of a subset of mRNAs.
mRNA 3' end processing is an essential step in gene expression. It is well established that canonical eukaryotic pre-mRNA 3' processing is carried out within a macromolecular machinery consisting of dozens of trans-acting proteins. However, it is unknown whether RNAs play any role in this process. Unexpectedly, we found that a subset of small nucleolar RNAs (snoRNAs) are associated with the mammalian mRNA 3' processing complex. These snoRNAs primarily interact with Fip1, a component of cleavage and polyadenylation specificity factor (CPSF). We have functionally characterized one of these snoRNAs and our results demonstrated that the U/A-rich SNORD50A inhibits mRNA 3' processing by blocking the Fip1-poly(A) site (PAS) interaction. Consistently, SNORD50A depletion altered the Fip1-RNA interaction landscape and changed the alternative polyadenylation (APA) profiles and/or transcript levels of a subset of genes. Taken together, our data revealed a novel function for snoRNAs and provided the first evidence that non-coding RNAs may play an important role in regulating mRNA 3' processing
Integrating Action Knowledge and LLMs for Task Planning and Situation Handling in Open Worlds
Task planning systems have been developed to help robots use human knowledge
(about actions) to complete long-horizon tasks. Most of them have been
developed for "closed worlds" while assuming the robot is provided with
complete world knowledge. However, the real world is generally open, and the
robots frequently encounter unforeseen situations that can potentially break
the planner's completeness. Could we leverage the recent advances on
pre-trained Large Language Models (LLMs) to enable classical planning systems
to deal with novel situations?
This paper introduces a novel framework, called COWP, for open-world task
planning and situation handling. COWP dynamically augments the robot's action
knowledge, including the preconditions and effects of actions, with
task-oriented commonsense knowledge. COWP embraces the openness from LLMs, and
is grounded to specific domains via action knowledge. For systematic
evaluations, we collected a dataset that includes 1,085 execution-time
situations. Each situation corresponds to a state instance wherein a robot is
potentially unable to complete a task using a solution that normally works.
Experimental results show that our approach outperforms competitive baselines
from the literature in the success rate of service tasks. Additionally, we have
demonstrated COWP using a mobile manipulator. Supplementary materials are
available at: https://cowplanning.github.io/Comment: arXiv admin note: substantial text overlap with arXiv:2210.0128
Improving Surgical Situational Awareness with Signed Distance Field: A Pilot Study in Virtual Reality
The introduction of image-guided surgical navigation (IGSN) has greatly
benefited technically demanding surgical procedures by providing real-time
support and guidance to the surgeon during surgery. \hi{To develop effective
IGSN, a careful selection of the surgical information and the medium to present
this information to the surgeon is needed. However, this is not a trivial task
due to the broad array of available options.} To address this problem, we have
developed an open-source library that facilitates the development of multimodal
navigation systems in a wide range of surgical procedures relying on medical
imaging data. To provide guidance, our system calculates the minimum distance
between the surgical instrument and the anatomy and then presents this
information to the user through different mechanisms. The real-time performance
of our approach is achieved by calculating Signed Distance Fields at
initialization from segmented anatomical volumes. Using this framework, we
developed a multimodal surgical navigation system to help surgeons navigate
anatomical variability in a skull base surgery simulation environment. Three
different feedback modalities were explored: visual, auditory, and haptic. To
evaluate the proposed system, a pilot user study was conducted in which four
clinicians performed mastoidectomy procedures with and without guidance. Each
condition was assessed using objective performance and subjective workload
metrics. This pilot user study showed improvements in procedural safety without
additional time or workload. These results demonstrate our pipeline's
successful use case in the context of mastoidectomy.Comment: First two authors contributed equally. 6 page
Morphological asymmetries of quasar host galaxies with Subaru Hyper Suprime-Cam
How does the host galaxy morphology influence a central quasar or vice versa?
We address this question by measuring the asymmetries of 2424 SDSS quasar hosts
at using broad-band () images from the Hyper Suprime-Cam
Subaru Strategic Program. Control galaxies (without quasars) are selected by
matching the redshifts and stellar masses of the quasar hosts. A two-step
pipeline is run to decompose the PSF and \sersic\ components, and then measure
asymmetry indices (, , and ) of each
quasar host and control galaxy. We find a mild correlation between host
asymmetry and AGN bolometric luminosity () for the full sample
(spearman correlation of 0.37) while a stronger trend is evident at the highest
luminosities (). This then manifests itself into quasar hosts
being more asymmetric, on average, when they harbor a more massive and highly
accreting black hole. The merger fraction also positively correlates with
and reaches up to 35\% for the most luminous. Compared to control
galaxies, quasar hosts are marginally more asymmetric (excess of 0.017 in
median at 9.4 level) and the merger fractions are similar (). We quantify the dependence of asymmetry on optical band which
demonstrates that mergers are more likely to be identified with the bluer bands
and the correlation between and asymmetry is also stronger in
such bands. We stress that the band dependence, indicative of a changing
stellar population, is an important factor in considering the influence of
mergers on AGN activity.Comment: 27 pages, 28 figure
Ferroelectric BaTiO3/SrTiO3 multilayered thin films for room-temperature tunable microwave elements
Ferroelectric BaTiO3/SrTiO3 with optimized c-axis-oriented multilayered thin films were epitaxially fabricated on (001) MgO substrates. The microstructural studies indicate that the in-plane interface relationships between the films as well as the substrate are determined to be (001)SrTiO3//(001)BaTiO3//(001)MgO and [100]SrTiO3//[100]BaTiO3//[100]MgO. The microwave (5 to 18 GHz) dielectric measurements reveal that the multilayered thin films have excellent dielectric properties with large dielectric constant, low dielectric loss, and high dielectric tunability, which suggests that the as-grown ferroelectric multilayered thin films can be developed for room-temperature tunable microwave elements and related device applications
In the eye of a hurricane there is quiet, for just a moment,-
CHI can be a multisensory overload. Attendees endure days of workshops, presentations, evening parties, and ephemeral interactions. This paper attempts to disrupt that onslaught of activities [9]. It draws inspiration from theories and methods already in HCI-eg mindfulness [1], reflective design [8], and slow design [4, 7]-to bring eight pages of silence to the conference. This is meant to disrupt CHI's busy schedule and help attendees foster resilience. In pursuit of these aims, the authors will use the time and pages offered by this paper to facilitate a group silence; quiet, for just a moment, in the midst of the hurricane that is CHI
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