Efficacy of intermittent prophylaxis vis a vis no prophylactic interventions in febrile seizure recurrence: randomised controlled trail

Background: To compare efficacy of intermittent prophylaxis during subsequent febrile episodes with antipyretics alone or antipyretics with anticonvulsant (clobazam) vis a vis no prophylactic interventions except need-based antipyretic measures in preventing recurrence of febrile seizures.Methods: This prospective randomized controlled interventional study was carried out in neurologically normal children. Study conducted over 14 months (March 2014 - May 2015), tertiary care hospital Mumbai. Inclusion criteria was, children aged from 6 month to 5 years with history of simple febrile seizure, lasting for less than 15 minutes, with Frequency less than one episode in 24 hours. Children with history of afebrile or complex febrile seizure, CNS comorbidity, family history of epilepsy, abnormal electroencephalogram, Unwillingness or non-feasibility of follow up were excluded from study. The patients were randomly grouped in A (No Prophylaxis n= 60), B (Antipyretic prophylaxis n=57) and C (Antipyretics + clobazam prophylaxis n=55). All cases were followed up telephonically every 15 days from date of first seizure as well as personal follow up at 1,3,6 months either in the hospital or at home. End point of study was taken as six months of follow-up from enrolment or lost-to-follow up. Efficacy of intervention was compared using chi-square test, Pearson chi-square test with/without Yates continuity correction and/or Fisher exact test, with p value of <0.05 as test of significance.Results: Sixty cases in group A developed febrile episodes and 6 of them developed recurrence of febrile seizures, with a recurrence rate of 10% among total cases and 9.67% among all febrile episodes. Recurrence rate was significantly higher (10%) in cases who did not receive any prophylactic intervention (Group A) as compared to pooled recurrence rate in group B and C together 1.78% (p=0.022).Conclusion: Regular antipyretic prophylaxis, alone or along with clobazam does not reduce the risk of recurrence in simple febrile seizures as compared to those who receive antipyretic intervention

Performance of some apricot (Prunus armeniaca L.) germplasm accessions for fruit quality traits in Himachal Pradesh

The present investigation was carried out in field gene bank of NBPGR Regional Station Phagli, Shimla during the year 2014-15. Twenty accessions of Prunus armeniaca L. namely St. Ambroise, Wenatchee, Nugget, Stirling, Nari, Harogem, Rakovslik, Viva Gold, IC-432145, Erevani, Safed Perchinar, KS-1, AS-1, AS-2, NJ-A96, Jordan Early, Vitillo, Shahib, Kalola and Anglo Arsani were evaluated for their tree, foliage, floral and fruit characters. St. Ambroise recorded maximum tree height (10.10 m) whereas minimum (2.47 m) was in Stirling. Shedding of leaf started from 29 th October (Nugget) and extended till 27 th November (Vitillo). Time of full bloom extended from 16 th March in Shahib to 23 rd March in Safed Perchinar. The longest duration (22 days) of flowering was recorded in Erevani and shortest (9 days) in Wenatchee. Time of fruit maturity was early (25 th May) in Shahib and late (26 th June) in Vitillo. Largest and heaviest fruits were observed in St. Ambroise (77.59 g) whereas smallest and lightest fruits were in Viva Gold (19.37 g). Maximum pulp to stone ratio was recorded in Safed Perchinar (33.21) and minimum in Nari (15.57). TSS content was maximum (19.56 °B) in Nari whereas minimum (10.73°B) in Anglo Arseni. Titratable acidity was recorded maximum (1.86 %) in AS-1 and minimum (0.76%) in IC 432145. Total sugar content ranged from 8.40 per cent in Anglo Arseni to 16.53 per cent in Nari. Total phenol content was maximum (89.57 mg/100 g) in AS-1 and minimum (70.41 mg/100 g) in IC432145. From the present investigation it may be concluded that St. Ambroise, Nari and Shahib can be used for gene source for developing new hybrid cultivars and St. Am-broise may be suggested for cultivation in wet temperate condition of Himachal Pradesh for its better quality

Flexible Overdenture: A Clinical Case Report

Abstract &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; An overdenture is a complete or partial removable denture supported by retained roots or teeth or implant studs, that is intended to provide improved support, stability, tactile and proprioceptive sensation and to reduce ridge resorption. It is a prosthesis that is supported both by mucosa and by a few remaining natural teeth that have been altered to permit the denture to fit over them. A Flexible denture on the other hand is made up of a thermoplastic injectable resin that offers superior flexibility, transparency for optimal aesthetics and stress crack resistance. It is monomer-free dental polymer with low flexural modulus. This clinical case report is an attempt to combine the advantages of two treatment modalities i.e. over denture and flexible denture to provide comfort, esthetics and function to a partially edentulous patient. &nbsp

Proceedings of National Conference on Relevance of Engineering and Science for Environment and Society

This conference proceedings contains articles on the various research ideas of the academic community and practitioners presented at the National Conference on Relevance of Engineering and Science for Environment and Society (R{ES}2 2021). R{ES}2 2021 was organized by Shri Pandurang Pratishthan’s, Karmayogi Engineering College, Shelve, Pandharpur, India on July 25th, 2021. Conference Title: National Conference on Relevance of Engineering and Science for Environment and SocietyConference Acronym: R{ES}2 2021Conference Date: 25 July 2021Conference Location: Online (Virtual Mode)Conference Organizers: Shri Pandurang Pratishthan’s, Karmayogi Engineering College, Shelve, Pandharpur, India