6,440 research outputs found

    Infrared heterodyne radiometer for airborne atmospheric transmittance measurements

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    An infrared heterodyne radiometer (IHR) was used to measure atmospheric transmittance at selected hydrogen fluoride (2.7 micrometer) and deuterium fluoride (3.8 micrometer) laser transitions. The IHR was installed aboard a KC-135 aircraft for an airborne atmospheric measurements program that used the sun as a backlighting source for the transmission measurements. The critical components are: a wideband indium antimonide (1nSb) photomixer, a CW HF/DF laser L0, a radiometric processor, and a 1900 K blackbody reference source. The measured heterodyne receiver sensitivity (NEP) is 1.3 x 10 to the -19th power W/Hz, which yields a calculated IHR temperature resolution accuracy of delta I sub S/-3 sub S = 0.005 for a source temperature of 1000 K and a total transmittance of 0.5. Measured atmospheric transmittance at several wavelengths and aircraft altitudes from 9.14 km (30,000 ft) to 13.72 km (45,000 ft) were obtained during the measurements program and have been compared with values predicted by the AFGL Atmospheric Line Parameter Compilation

    Elimination of pain improves specificity of clinical diagnostic criteria for adult chronic rhinosinusitis

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    Objective Determine whether the elimination of pain improves accuracy of clinical diagnostic criteria for adult chronic rhinosinusitis. Study Design Retrospective cohort study. Methods History, symptoms, nasal endoscopy, and computed tomography (CT) results were analyzed for 1,186 adults referred to an academic otolaryngology clinic with presumptive diagnosis of chronic rhinosinusitis. Clinical diagnosis was rendered using the 1997 Rhinosinusitis Taskforce (RSTF) Guidelines and a modified version eliminating facial pain, ear pain, dental pain, and headache. Results Four hundred seventy-nine subjects (40%) met inclusion criteria. Among subjects positive by RSTF guidelines, 45% lacked objective evidence of sinonasal inflammation by CT, 48% by endoscopy, and 34% by either modality. Applying modified RSTF diagnostic criteria, 39% lacked sinonasal inflammation by CT, 38% by endoscopy, and 24% by either modality. Using either abnormal CT or endoscopy as the reference standard, modified diagnostic criteria yielded a statistically significant increase in specificity from 37.1% to 65.1%, with a nonsignificant decrease in sensitivity from 79.2% to 70.3%. Analysis of comorbidities revealed temporomandibular joint disorder, chronic cervical pain, depression/anxiety, and psychiatric medication use to be negatively associated with objective inflammation on CT or endoscopy. Conclusion Clinical diagnostic criteria overestimate the prevalence of chronic rhinosinusitis. Removing facial pain, ear pain, dental pain, and headache increased specificity without a concordant loss in sensitivity. Given the high prevalence of sinusitis, improved clinical diagnostic criteria may assist primary care providers in more accurately predicting the presence of inflammation, thereby reducing inappropriate antibiotic use or delayed referral for evaluation of primary headache syndromes. Level of Evidence4. Laryngoscope, 127:1011-1016, 201

    Resistance of sugarcane cultivars to Diataea saccharalis.

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    The objective of this work was to evaluate the ovipositions preference of Diatraea saccharalis and the effect of ten sugarcane cultivars on larval development. Oviposition preference was assessed under greenhouse condition by three releases of couples of moths, with subsequent counting of egg masses and eggs per plant. In order to evaluate the effet of the cultivars on larval development, each plant was infected with about 150 eggs, and, 29 days later, the total number of internodes, number of bored internodes, number of life forms found, larval and pupal weight and length, and the width of larval head capsule were evaluated.TĂ­tulo em portuguĂȘs: ResistĂȘncia de cultivares de cana?de?açĂșcar a Diatraea saccharalis

    Electronic Band Structure of the Two-Dimensional Surface-State Bands of the (1×1) and (1×2) Phases of Bi/GaSb(110)

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    The surface-state bands of the (1×1) and (1×2) phases of Bi/GaSb(110) have been probed using angle-resolved ultraviolet photoemission spectroscopy with synchrotron radiation. Four Bi-induced surface-state bands have been identified for both the (1×1) and the (1×2) phases. The bands with the lowest binding energies (SI and SII) have been attributed to intrachain bonding in the Bi overlayer and the higher-binding-energy bands (SIII and SIV) to overlayer states involved in the back bonding of the overlayer to the substrate. Based on initial-state dispersion measurements, we conclude that the Bi chains in the epitaxial overlayer remain intact throughout the phase transition. We propose a model for the overlayer structure of the (1×2) phase of Bi/GaSb(110)

    Prospective longitudinal study of coagulation profiles in children with hypoplastic left heart syndrome from stage I through Fontan completion

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    ObjectiveThe risk for thrombosis is increased after the Fontan operation. It is unknown whether children with univentricular heart disease have an intrinsic coagulation anomaly or acquire a defect in coagulation during the course of the staged repair. This prospective, longitudinal study evaluated changes in coagulation profiles in a cohort of patients with hypoplastic left heart syndrome from stage I palliation through completion of the Fontan operation.MethodsThirty-seven patients with hypoplastic left heart syndrome were enrolled prospectively, and the concentration of factors II, V, VII, VIII, IX, X, proteins C and S, fibrinogen, antithrombin, serum albumin, and liver enzymes were measured before stage I palliation (mean age 4 ± 2 days), before bidirectional Glenn (mean age 5.9 ± 1.8 months), before the Fontan procedure (mean age 27.1 ± 6.6 months), and after the Fontan procedure (mean age 49 ± 17.6months). Healthy children were used as age-matched controls for coagulation factors. Demographic, hemodynamic variables, and elapsed time after the Fontan procedure were evaluated as possible predictors of coagulation abnormalities.ResultsSignificantly lower levels of both procoagulation and anticoagulation factors were demonstrated through to completion of the Fontan procedure. After the Fontan procedure, there was a significantly higher factor VIII level (P < .005) but no correlation with hemodynamic variables or liver function.ConclusionThis longitudinal study in patients with identical cardiac disease and staged surgical procedures confirms the increase in factor VIII level after the Fontan procedure. This is an acquired defect, and although the cause remains to be determined, monitoring factor VIII levels after the Fontan operation could indicate a subset of patients at risk for thrombosis

    Prospective longitudinal study of coagulation profiles in children with hypoplastic left heart syndrome from stage I through Fontan completion

    Get PDF
    ObjectiveThe risk for thrombosis is increased after the Fontan operation. It is unknown whether children with univentricular heart disease have an intrinsic coagulation anomaly or acquire a defect in coagulation during the course of the staged repair. This prospective, longitudinal study evaluated changes in coagulation profiles in a cohort of patients with hypoplastic left heart syndrome from stage I palliation through completion of the Fontan operation.MethodsThirty-seven patients with hypoplastic left heart syndrome were enrolled prospectively, and the concentration of factors II, V, VII, VIII, IX, X, proteins C and S, fibrinogen, antithrombin, serum albumin, and liver enzymes were measured before stage I palliation (mean age 4 ± 2 days), before bidirectional Glenn (mean age 5.9 ± 1.8 months), before the Fontan procedure (mean age 27.1 ± 6.6 months), and after the Fontan procedure (mean age 49 ± 17.6months). Healthy children were used as age-matched controls for coagulation factors. Demographic, hemodynamic variables, and elapsed time after the Fontan procedure were evaluated as possible predictors of coagulation abnormalities.ResultsSignificantly lower levels of both procoagulation and anticoagulation factors were demonstrated through to completion of the Fontan procedure. After the Fontan procedure, there was a significantly higher factor VIII level (P < .005) but no correlation with hemodynamic variables or liver function.ConclusionThis longitudinal study in patients with identical cardiac disease and staged surgical procedures confirms the increase in factor VIII level after the Fontan procedure. This is an acquired defect, and although the cause remains to be determined, monitoring factor VIII levels after the Fontan operation could indicate a subset of patients at risk for thrombosis

    Testbeam and Laboratory Characterization of CMS 3D Pixel Sensors

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    The pixel detector is the innermost tracking device in CMS, reconstructing interaction vertices and charged particle trajectories. The sensors located in the innermost layers of the pixel detector must be upgraded for the ten-fold increase in luminosity expected with the High- Luminosity LHC (HL-LHC) phase. As a possible replacement for planar sensors, 3D silicon technology is under consideration due to its good performance after high radiation fluence. In this paper, we report on pre- and post- irradiation measurements for CMS 3D pixel sensors with different electrode configurations. The effects of irradiation on electrical properties, charge collection efficiency, and position resolution of 3D sensors are discussed. Measurements of various test structures for monitoring the fabrication process and studying the bulk and surface properties, such as MOS capacitors, planar and gate-controlled diodes are also presented.Comment: 14 page

    Analysis and Modification of Amorphous and Partially-Crystalline Thin Films

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    Thin films of light atomic weight elements in amorphous, partially-crystalline, or crystalline forms have applications in a broad range of technologies. For example, amorphous tetrahedral carbon (a-tC) and polymeric thin films impact electronic materials technology as electron- and light-emitting device elements, respectively. A lack of crystallinity introduces complexity in the experimental and theoretical characterization of these materials but is not necessarily a limiting factor in their performance. While the growth process is clearly a major factor governing the physical properties of a film, interactions with the substrate are also important, so surface and interface analysis provides an important complement to bulk measurements. This paper focuses on several approaches in the characterization and modification of thin films made possible by recent experimental advances. The structural and electronic properties of two model systems are considered as examples: a-tC thin films grown by pulsed laser deposition (PLD) and polyaniline thin films grown by vapor deposition. First, scanning probe microscopies and X-ray scattering are used to investigate the structural aspects of a-tC films as a function of PLD growth conditions. The possible connection of nanoscale surface modification and characterization with electron emission properties will be discussed. Second, the results of inelastic scattering spectroscopy and other surface techniques will be discussed to obtain information on both interfacial aspects of the growth of polyaniline thin films and microscopic and macroscopic aspects of electrical conductivity upon doping. Comparisons will be made with other studies that address properties of analogous crystalline systems as appropriate. A brief assessment of the broader problem of analyzing these systems will be given

    Viewpoint: Estimating the causal effects of policies and programs

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    Estimation, inference and interpretation of the causal effects of programs and policies have all advanced dramatically over the past 25 years. We highlight three particularly important intellectual trends: an improved appreciation of the substantive importance of heterogeneous responses and of their methodological implications, a stronger focus on internal validity brought about by the “credibility revolution,” and the scientific value that follows from grounding estimation and interpretation in economic theory. We discuss a menu of commonly employed partial equilibrium approaches to the identification of causal effects, emphasizing that the researcher’s central intellectual contribution always consists of making an explicit case for a specific causal interpretation given the relevant economic theory, the data, the institutional context and the economic question of interest. We also touch on the importance of general equilibrium effects and full cost–benefit analyses.RĂ©sumĂ©Point de vue: Sur l’estimation des effets causatifs des politiques et programmes. Dans le monde de l’estimation, l’infĂ©rence et l’interprĂ©tation des effets causatifs des programmes et des politiques, il y a eu des progrĂšs dramatiques au cours des derniers 25 ans. Les auteurs soulignent trois tendances intellectuelles particuliĂšrement importantes : une apprĂ©ciation amĂ©liorĂ©e de l’importance substantielle des rĂ©ponses hĂ©tĂ©rogĂšnes et de leur importance mĂ©thodologique, une focalisation plus robuste sur la validitĂ© interne engendrĂ©e par la « rĂ©volution de la crĂ©dibilitĂ© », et la valeur scientifique qui dĂ©coule d’un ancrage de l’estimation et de l’interprĂ©tation dans la thĂ©orie Ă©conomique. On discute un Ă©ventail d’approches d’équilibre partiel Ă  l’identification des effets causatifs, mettant au premier plan que la contribution intellectuelle centrale du chercheur consiste Ă  bĂątir un argumentaire explicite pour une interprĂ©tation causale spĂ©cifique compte tenu de la thĂ©orie Ă©conomique pertinente, des donnĂ©es, du contexte institutionnel, et de la question Ă©conomique d’intĂ©rĂȘt. On mentionne aussi l’importance des effets d’équilibre gĂ©nĂ©ral et des analyses de tous les coĂ»ts et avantages.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/134884/1/caje12217.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/134884/2/caje12217_am.pd
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