Occurrence of HCV infection in patients viral hepatitis in the Infectious Diseases Clinic, Stip, 1991-1992

A number of 52 HBsAg negative patients were investigated for the presence of HCV antibodies and only in 3 patients was the test for HCV antibodies positive (5.77% of the patients with hepatitis which is HBsAg negative). The possible explanation for the low per cent of HCV antibodies is considered in the patients with NANB hepatitis

HCV-antibodies in orthopaedic patients

The presence of HCV antibodies in patients undergoing minor orthopedic operacions and in patients with inplanted endoprothesis in the postoperative period was determined: in the first group (38 patients) no patients were HCV antibodies positive, in the second group (82) patients) 4 patients were HCV antibodies positive (4,88% in orthopaedic patients and 1.15% in healthy blood donors, a prevalence of HCV antibodies 4,24 higher)

Clinical importance of imunoglobulin classes of HCV antibodies

In the Department of haemostasis and thrombosis of the Institute of Blood Transfusion, Skopje, a method has been developed for the identification of immunoglobulin classes of HCV antibodies, the differentiation of immunoglobulin classes of HCV antibodies gives the possibility of identifying the acute type of HCV infection (only IgM type of HCV antibodies present) and the chronic type of HCV infection (both IgG and IgM type of HCV antibodies present). Both the macro-and micro-ELISA system are employed in the immunoglobulin classes identification of HCV antibodies. The method we used is a double sandwich ELISA technique with the use of monospecific antisera for IgG and IgM