10 research outputs found

    The Santorini-Amorgos Shear Zone: Evidence for Dextral Transtension in the South Aegean Back-Arc Region, Greece

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    Bathymetric and seismic data provide insights into the geomorphological configuration, seismic stratigraphy, structure, and evolution of the area between Santorini, Amorgos, Astypalea, and Anafi islands. Santorini-Amorgos Shear Zone (SASZ) is a NE-SW striking feature that includes seven basins, two shallow ridges, and hosts the volcanic centers of Santorini and Kolumbo. The SASZ initiated in the Early Pliocene as a single, W-E oriented basin. A major reorganization of the geodynamic regime led to (i) reorientation of the older faults and initiation of NE-SW striking ones, (ii) disruption of the single basin and localized subsidence and uplift, (iii) creation of four basins out of the former single one (Anafi, Amorgos South, Amorgos North, and Kinairos basins), (iv) rifting of the northern and southern margins and creation of Anydros, Astypalea North, and Astypalea South basins, and (v) uplift of the ridges. Dextral shearing and oblique rifting are accommodated by NE-SW striking, dextral oblique to strike-slip faults and by roughly W-E striking, normal, transfer faults. It is suggested here that enhanced shearing in NE-SW direction and oblique rifting may be the dominant deformation mechanism in the South Aegean since Early Quaternary associated with the interaction of North Anatolian Fault with the slab roll-back

    Genotoxic and Antigenotoxic Assessment of Chios Mastic Oil by the In Vitro Micronucleus Test on Human Lymphocytes and the In Vivo Wing Somatic Test on Drosophila

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    International audienceChios mastic oil (CMO), the essential oil derived from Pistacia lentiscus (L.) var. chia (Duham), has generated considerable interest because of its antimicrobial, anticancer, antioxidant and other beneficial properties. In the present study, the potential genotoxic activity of CMO as well as its antigenotoxic properties against the mutagenic agent mitomycin-C (MMC) were evaluated by employing the in vitro Cytokinesis Block MicroNucleus (CBMN) assay and the in vivo Somatic Mutation And Recombination Test (SMART). In the in vitro experiments, lymphocytes were treated with 0.01, 0.05 and 0.10% (v/v) of CMO with or without 0.05 μg/ml MMC, while in the in vivo assay Drosophila larvae were fed with 0.05, 0.10, 0.50 and 1.00% (v/v) of CMO with or without 2.50 μg/ml MMC. CMO did not significantly increase the frequency of micronuclei (MN) or total wing spots, indicating lack of mutagenic or recombinogenic activity. However, the in vitro analysis suggested cytotoxic activity of CMO. The simultaneous administration of MMC with CMO did not alter considerably the frequencies of MMC-induced MN and wing spots showing that CMO doesn't exert antigenotoxic or antirecombinogenic action. Therefore, CMO could be considered as a safe product in terms of genotoxic potential. Even though it could not afford any protection against DNA damage, at least under our experimental conditions, its cytotoxic potential could be of interest
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