583 research outputs found

    Here, there, in between, beyond…: Identity negotiation and sense of belonging among Southern Europeans in the UK and Germany

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    Whilst most of the research on intra-EU mobility has mainly focused on the reasons behind young Southern Europeans leaving their home countries, and secondly on their experiences within the new context, little is known about their sense of belonging and identities. This article aims to fill this gap by exploring Italian and Spanish migrants\u2019 social identity repositioning and the cultural change characterising their existential trajectories. Drawing on 69 semi-structured interviews with Italians and Spaniards living in London and Berlin, this article shows that the sense of belonging to one or more political communities and boundary work are related to individual experiences and can change due to structural eventualities such as the Brexit referendum. While identification with the host society is rare, attachment to the home country is quite common as a result of people\u2019s everyday experiences. Cultural changes and European/cosmopolitan identification are linked to exposure to new environments and interaction with new cultures, mostly concerning those with previous mobility experience, as well as to a sentiment of non-acceptance in the UK. However, such categories are not rigid, but many times self-identification and attachments are rather blurred also due to the uncertainty around the duration of the mobility project. This makes individual factors (gender, age, family status, employment, education) that are often considered as determinants of identification patterns all but relevant

    The Efficiency Gap

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    Parameter estimation via M- and Z-estimation is broadly considered to be equally powerful in semiparametric models for one-dimensional functionals. This is due to the fact that, under sufficient regularity conditions, there is a one-to-one relation between the corresponding objective functions - strictly consistent loss functions and oriented strict identification functions - via integration and differentiation. When dealing with multivariate functionals such as multiple moments, quantiles, or the pair (Value at Risk, Expected Shortfall), this one-to-one relation fails due to integrability conditions: Not every identification function possesses an antiderivative. The most important implication of this failure is an efficiency gap: The most efficient Z-estimator often outperforms the most efficient M-estimator, implying that the semiparametric efficiency bound cannot be attained by the M-estimator in these cases. We show that this phenomenon arises for pairs of quantiles at different levels and for the pair (Value at Risk, Expected Shortfall), where we illustrate the gap through extensive simulations

    Prvi nalaz tupousne barakude Sphyraena chrysotaenia (Klunzinger, 1884) i indopacifičke vrste ježinca Diadema setosum (Leske, 1778) u morskom zaštićenom području otoka Zakintos, Jonsko more, Grčka

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    In 2021, three specimens of the Lessepsian yellowstripe barracuda Sphyraena chrysotaenia and eight specimens of the Indo-Pacific needle-spined sea urchin Diadema setosum were recorded along the coasts of Zakynthos Island, some within the Marine Protected Area.U 2021. godini, tri primjerka lesepsijske tupousne barakude Sphyraena chrysotaenia i osam primjeraka indo-pacifičke vrste ježinca Diadema setosum su pronađeni u području oko otoka Zakintos, neki unutar morskog zaštićenog područja

    Stability of the non-extremal enhancon solution I: perturbation equations

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    We consider the stability of the two branches of non-extremal enhancon solutions. We argue that one would expect a transition between the two branches at some value of the non-extremality, which should manifest itself in some instability. We study small perturbations of these solutions, constructing a sufficiently general ansatz for linearised perturbations of the non-extremal solutions, and show that the linearised equations are consistent. We show that the simplest kind of perturbation does not lead to any instability. We reduce the problem of studying the more general spherically symmetric perturbation to solving a set of three coupled second-order differential equations.Comment: 20 pages, 1 figure, references added, typos fixed, version to appear in PR

    Leber's hereditary optic neuropathy with late disease onset: clinical and molecular characteristics of 20 patients

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    Background: Leber's hereditary optic neuropathy (LHON) is a mitochondrial disease that typically causes bilateral blindness in young men. Here we describe the clinical and molecular characteristics of 20 patients with disease onset after the age of 50 years (late onset-LHON). Methods: From a cohort of 251 affected and 277 unaffected LHON carriers, we identified 20 patients with onset of visual loss after the age of 50 years. Using structured questionnaires, data including basic demographic details, age of onset, progression of visual loss and severity as well as exposure to possible environmental triggers including alcohol, smoking and illicit drugs were retrospectively collected. Groups were compared using the Mann-Whitney-U-Test for two independent groups of sampled data. Results: The proportion of late onset-LHON in our cohort was 8% (20 patients, 15 males, 5 females). The mtDNA mutations m. 11778G  > A and m. 3460G  > A were found in 16 and 4 patients, respectively. Among 89 asymptomatic carriers above the age of 50 years (28 males, 61 females), the mtDNA mutations m. 11778G > A, m. 3460G  > A and m. 14484 T  > C were found in 60, 12 and 17 carriers, respectively. Late onset-LHON patients had significantly higher mean cumulative tobacco and alcohol consumption compared with unaffected carriers. However, there was no significant difference between late onset-and typical LHON patients with regard to daily tobacco and weekly alcohol consumption before disease onset. Conclusion: As already shown for typical LHON, alcohol consumption and smoking are important trigger factors also for the late manifestation. LHON should be considered in the differential diagnosis of subacute blindness even in older patients

    Cost-effectiveness of short-protocol emergency brain MRI after negative non-contrast CT for minor stroke detection

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    OBJECTIVES To investigate the cost-effectiveness of supplemental short-protocol brain MRI after negative non-contrast CT for the detection of minor strokes in emergency patients with mild and unspecific neurological symptoms. METHODS The economic evaluation was centered around a prospective single-center diagnostic accuracy study validating the use of short-protocol brain MRI in the emergency setting. A decision-analytic Markov model distinguished the strategies \textquotedblno additional imaging\textquotedbl and \textquotedbladditional short-protocol MRI\textquotedbl for evaluation. Minor stroke was assumed to be missed in the initial evaluation in 40% of patients without short-protocol MRI. Specialized post-stroke care with immediate secondary prophylaxis was assumed for patients with detected minor stroke. Utilities and quality-of-life measures were estimated as quality-adjusted life years (QALYs). Input parameters were obtained from the literature. The Markov model simulated a follow-up period of up to 30 years. Willingness to pay was set to 100,000perQALY.Costeffectivenesswascalculatedanddeterministicandprobabilisticsensitivityanalysiswasperformed.RESULTSAdditionalshortprotocolMRIwasthedominantstrategywithoverallcostsof100,000 per QALY. Cost-effectiveness was calculated and deterministic and probabilistic sensitivity analysis was performed. RESULTS Additional short-protocol MRI was the dominant strategy with overall costs of 26,304 (CT only: $27,109). Cumulative calculated effectiveness in the CT-only group was 14.25 QALYs (short-protocol MRI group: 14.31 QALYs). In the deterministic sensitivity analysis, additional short-protocol MRI remained the dominant strategy in all investigated ranges. Probabilistic sensitivity analysis results from the base case analysis were confirmed, and additional short-protocol MRI resulted in lower costs and higher effectiveness. CONCLUSION Additional short-protocol MRI in emergency patients with mild and unspecific neurological symptoms enables timely secondary prophylaxis through detection of minor strokes, resulting in lower costs and higher cumulative QALYs. KEY POINTS • Short-protocol brain MRI after negative head CT in selected emergency patients with mild and unspecific neurological symptoms allows for timely detection of minor strokes. • This strategy supports clinical decision-making with regard to immediate initiation of secondary prophylactic treatment, potentially preventing subsequent major strokes with associated high costs and reduced QALY. • According to the Markov model, additional short-protocol MRI remained the dominant strategy over wide variations of input parameters, even when assuming disproportionally high costs of the supplemental MRI scan

    New Mediterranean Biodiversity Records (April, 2014)

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    According to reports, the following 16 species have extended their distribution to other Mediterranean areas or have made a new appearance in other regions. The first category includes the following organisms: The rare and common Indo-Pacific seaweed Codium arabicum (Lebanese coasts), the acari Thalassarachna affinis (Marmara Sea), and the non-indigenous nudibranch Flabellina rubrolineata, which has also been found in many other areas of the Aegean Sea. In addition, the rare sea slug Thecacera pennigera (Piccolo of Taranto), the fangtooth moray Enchelycore anatina (National Marine Park of Zakynthos, Ionian Sea), the carangid Seriola fasciata (Gulf of Antalya), Lagocephalus sceleratus (SE. Ionian Sea), the reticulated leatherjacket Stephanolepis diaspros (Slovenia, N. Adriatic Sea), the marbled stingray, Dasyatis marmorata (NE Levantine), the starry smooth-hound Mustelus asterias (Iskenderun Bay, NE Mediterranean), the cephalopod Ommastrephes bartramii (Ionian Sea) have also been reported. The Atlantic crab Dyspanopeus sayi has expanded to many Italian areas and the blue crab Callinectes sapidus to a lake in N. Greece and in the S. Adriatic Sea. Finally, Farfantepenaeus aztecus has been found in the Ionian Sea, thus showing its wide expansion in the Mediterranean. The larval stages of Faccionella oxyrhyncha have been found, after many years, in the Aegean Sea and the first report of an existence on intersexual acari Litarachna duboscqi in Split(Adriatic Sea) was reported
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