171 research outputs found
TESTING THE EFFICIENCY MARKET HYPOTHESIS FOR THE ROMANIAN STOCK MARKET
Efficient Market Hypothesis has dominated the field of research on capital markettheory. It states that asset prices are rationally connected to economic realities and alwaysincorporate all the information available to the market. In this way, securities markets are seen asefficient in reflecting information about individual stocks or about the stock market as a whole. Alarge number of theoretical, as well as empirical papers around the world have had as objectivetesting this hypothesis. Beside reviewing the most important part of literature in this respect, thepaper has as aim testing the Efficient Market Hypothesis on Bucharest Stock Exchange. The testedhypothesis is carried on time series of stock index BET (daily observations), for the period 2000-2009. The econometrical results assert that the weak form of the efficiency market hypothesis isaccomplished.efficiency market hypothesis, Romanian stock exchange, BET
An empirical analysis of the interlinkages between financial sector and economic growth
There is a growing literature body which examines the connections between financial status and economic growth. The aim of this paper is to examine the mechanism through which this positive connection is realized. The methodology is based on a pool data regression with dynamic of real GDP as dependent variable and some key variables of the financial sector. The main output of our study consists in the thesis that the financial status matter for the economic growth.finance, growth, cost of capital, yield
The companies financial architecture and the market values: is there an interlinkage ? The case of Bucharest Stock Exchange
Nowadays there is a large debate on whether the financial information proves any relevance for the investors´ prediction of the securities market values/stock prices. The paper focuses, besides reviewing some important literature concerning this issue, on an empirical analysis taking into consideration 44 companies listed on Bucharest Stock Exchange based on pool data linear regressions. It is true that the most recent research state that there is an important evidence of a deterioration of the relationship between accounting information and stock prices. Although, the main findings of this paper consist in that there are certain aspects which should be further examined for a more reliable conceptual approach. In addition, it concludes that - even in the case of an emergent capital market as Bucharest Stock Exchange - it can be found mixed evidences to support the importance of financial information in portfolio’ management decisions. In a sense or another, the paper state overall that the financial information matter for market determination of financial assets’ values.capital markets, financial information, financial assets’ valuation
WATER ENERGY IN HYDROAMELIORATIVE SYSTEMS USING THE HYDRAULIC TRANSFORMER TYPE A. BARGLAZAN AND THE HYDRAULIC HAMMER (HYDRAULIC PUMP)
This paper presents two examples of exploitation of water energy that can be used in the irrigation field. First of theseexamples is the hydraulic transformer type A. Barglazan used for irrigation, pumped water is taken directly from theriver’s well, using a hydraulic pump which simultaneously carried out a double transformation in this way: hydraulicenergy into mechanic energy and mechanical energy into hydraulic energy. Technology preparation and devices designwas done in record time, seeing that this constructive solution is more robust, reliable and with improved energyperformance versus the laboratory prototype. The experimental research which was made at 1:1 scale proved theirgood function over time. Another example is the hydraulic hammer (hydraulic pump) that uses low-head energy topump water, with a global efficiency of about 10 - 50%. Currently, the new situation of private ownership of landprovides conditions for new pumping microstations to be made where irrigation is necessary and optimal hydrauliclocations exist
Bioactive Plant Compounds in Coffee Charcoal (Coffeae carbo) Extract Inhibit Cytokine Release from Activated Human THP-1 Macrophages
The herbal preparation coffee charcoal is produced by over-roasting and milling green
dried Coffea arabica L. seeds, and has a long-standing tradition in the treatment of inflammatory and
gastrointestinal disorders. Its therapeutic properties are commonly attributed to adsorptive and
astringent effects. This insufficiently explains its mode of action, especially when used in the treatment
of inflammatory diseases in lower dosages. Our investigations aimed to identify bioactive secondary
plant metabolites affecting cytokine-signaling. Thus, a phytochemical analysis of coffee charcoal
extract was conducted using HPLC and LC/MS. Trigonelline, neochlorogenic acid, chlorogenic
acid, caffeine, cryptochlorogenic acid, feruloylquinic acid isomers, and a caffeoylquinolacton were
identified in the extract. Subsequently, the effects of coffee charcoal extract, chlorogenic acid isomers,
their metabolite caffeic acid, caffeine, and trigonelline on cytokine (TNF, IL-6, MCP-1) release from
LPS-challenged human THP-1 macrophages were examined to evaluate anti-inflammatory activity.
Coffee charcoal showed concentration-dependent mild-to-medium inhibitory effects. The chlorogenic
acid isomers and caffeic acid inhibited the TNF release, with cryptochlorogenic acid exerting the most
distinct effects, as well as decreasing the release of IL-6 and MCP-1. In addition, scanning electron
microscopic images provided an impression of the particle constitution, indicating a larger particle
size and less structured surface of coffee charcoal in comparison to activated charcoal. In conclusion,
our findings underline that beyond adsorptive effects, coffee charcoal exhibits pharmacological
properties, which derive from a spectrum of secondary plant metabolites and support the therapeutic
use in inflammatory diseases. Chlorogenic acids, particularly cryptochlorogenic acid, appear as
pivotal bioactive compounds
Reduced expression of THRβ in papillary thyroid carcinomas: relationship with BRAF mutation, aggressiveness and miR expression
Purpose
Down-regulation of thyroid hormone receptor beta (THRβ) gene has been described in several human malignancies, including thyroid cancer. In this study, we analyzed THRβ mRNA expression in surgical specimens from a series of human papillary thyroid carcinomas (PTCs), characterized by their genotypic and clinical–biological features.
Methods
Thirty-six PTCs were divided into two groups according to the 2009 American Thyroid Association risk classification (17 low, 19 intermediate), and each group was divided into subgroups based on the presence or absence of the BRAFV600E mutation (21 BRAF mutated, 15 BRAF wild type). Gene expression was analyzed using fluidic cards containing probes and primers specific for the THRβ gene, as well as for genes of thyroperoxidase (TPO), sodium/iodide symporter (NIS), thyroglobulin (Tg) and thyroid stimulating hormone receptor (TSH-R) and for some miRNAs involved in thyroid neoplasia and targeting THRβ. The mRNA levels of each tumor tissue were compared with their correspondent normal counterpart.
Results
THRβ transcript was down-regulated in all PTCs examined. No significant differences were found between intermediate- vs low-risk PTCs patients, and BRAF-mutated vs BRAF wild-type groups. THRβ expression was directly correlated with NIS, TPO, Tg and TSH-R, and inversely correlated to miR-21, -146a, -181a and -221 expression.
Conclusions
Our results demonstrate that down-regulation of THRβ is a common feature of PTCs. While it is not associated with a more aggressive phenotype of PTC, it correlates with the reduction of all the markers of differentiation and is associated with overexpression of some miRNAs supposed to play a role in thyroid tumorigenesis
The companies financial architecture and the market values: is there an interlinkage ? The case of Bucharest Stock Exchange
Nowadays there is a large debate on whether the financial information proves any relevance for the investors´ prediction of the securities market values/stock prices. The paper focuses, besides reviewing some important literature concerning this issue, on an empirical analysis taking into consideration 44 companies listed on Bucharest Stock Exchange based on pool data linear regressions. It is true that the most recent research state that there is an important evidence of a deterioration of the relationship between accounting information and stock prices. Although, the main findings of this paper consist in that there are certain aspects which should be further examined for a more reliable conceptual approach. In addition, it concludes that - even in the case of an emergent capital market as Bucharest Stock Exchange - it can be found mixed evidences to support the importance of financial information in portfolio’ management decisions. In a sense or another, the paper state overall that the financial information matter for market determination of financial assets’ values
An empirical analysis of the interlinkages between financial sector and economic growth
There is a growing literature body which examines the connections between financial status and economic growth. The aim of this paper is to examine the mechanism through which this positive connection is realized. The methodology is based on a pool data regression with dynamic of real GDP as dependent variable and some key variables of the financial sector. The main output of our study consists in the thesis that the financial status matter for the economic growth
An empirical analysis of the interlinkages between financial sector and economic growth
There is a growing literature body which examines the connections between financial status and economic growth. The aim of this paper is to examine the mechanism through which this positive connection is realized. The methodology is based on a pool data regression with dynamic of real GDP as dependent variable and some key variables of the financial sector. The main output of our study consists in the thesis that the financial status matter for the economic growth
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