NASYA-MOST VITAL THERAPEUTIC INTERVENTION OF PANCHAKARMA-A REVIEW

Ayurveda is a Science and art of appropriate living which helps to achieve longevity. Panchakarma present a unique approach of Ayurveda to therapy with specially designed five procedures of internal purification of the body. One of the Panchakarma, the Nasyakarma is considered the best and the most specific procedure for disease of Urdhvajatrugatarogas like Pratishyay, Shirahshoola etc. It is also useful in other systemic diseases like Ardita, Kampavata. According to Ayurveda, the nose is the gate way to Shirah. So, systemically performed Nasyakarma cures almost all the diseases of Urdhvajatrugata rogas. Other procedures of Panchakarma are also very effective in numerous diseases according to condition but Nasya Karma is very easy to perform and there are no many strict regimens to follow during Nasya Karma but it will give effectual results in loads of diseases due to direct contact with nerve terminals by the nasal mucosa. So, it is demand of time to know about Nasyakarma and its importance. In this direction, to evaluate the actual efficacy of different Ayurveda treatment modalities; few works on Nasya Karma are compiled here. In current attempt, it has been planned to review as such works done on Nasyakarma. By this Present study it can be stated that in various diseases Nasya Karma is found to be significantly effective. It proved to be a better therapy as compared to only oral drug because it provides affect for longer duration than oral drug

Skull-base Ewing sarcoma with multifocal extracranial metastases

Intracranial occurrence of Ewing sarcoma (ES) is unusual, with a skull-base location being anecdotal. We report a 29-year-old man who presented with rapidly progressive ophthalmoplegia, and was found to be harboring an infiltrative lesion involving the sphenoid sinus, sella, and clivus. He underwent trans-sphenoidal decompression of the lesion which was histologically suggestive of ES. He developed paraparesis 2 weeks after commencing adjuvant therapy. Imaging revealed two thoracic extradural lesions and florid vertebral and pulmonary metastases. This is the first report in indexed literature of a primary intracranial ES on the skull-base with disseminated extracranial disease

Sugammadex-Associated Hypotension, Bradycardia, Asystole, and Death

On December 16, 2015, the Food and Drug Administration (FDA) in the United States approved sugammadex (Bridion, Merck and Co), a modified gamma-cyclodextrin, to be used as a reversal agent. It is a first and unique selective nondepolarizing steroidal muscle relaxant (NDSMR) binding agent with a great affinity for rocuronium and vecuronium. However, there have been several recently published case reports of bradycardia and asystole immediately after sugammadex administration for the reversal. This report presents a case of sugammadex administration followed by rapidly progressing bradycardia leading to asystole and subsequent death. The family has provided the written consent to share this case report

Case report on intravenous octreotide for the treatment of intraoperative vasoplegia following thymoma resection

Octreotide is a somatostatin analog known for its role in the treatment of acute variceal bleeding, enterocutaneous fistula and carcinoid syndrome. The reduction of portal pressure from splanchnic vasoconstriction has been attributed to the inhibition of nitric oxide synthesis, guanylate cyclase and release of glucagon. Octreotide has many therapeutic applications as a result of the ubiquitous nature of somatostatin receptors throughout the body. The effects of octreotide on vascular tone make it potentially useful in the treatment of intraoperative vasoplegia, hypotension with low systemic vascular resistance with preserved cardiac output that is refractory to adrenergic agonists. We present a case in which a patient undergoing thymoma resection developed vasoplegia that was effectively treated with octreotide. We believe that this case illustrates the need for further investigation on the potential efficacy of octreotide as an adjunct for the treatment of vasoplegia and other forms of shock

The Impact of telemedicine in the postoperative care of the neurosurgery patient in an outpatient clinic : a unique perspective of this valuable resource in the developing world - an experience of more than 3000 teleconsultations

Telemedicine has always been used as a teleconsultation tool in neurological emergencies (e.g., triage in head injuries, stroke, and cerebrovascular accidents). At Sri Sathya Sai Institute of Higher Medical Sciences, Bangalore, India, we have been operating two teleconsultation sessions per week for the postoperative patient population, addressing routine follow-up and semiemergent conditions in this cohort of patients. At our center more than 80% of the neurosurgical procedures are conducted in patients traveling more than 1500 km. Telemedicine as a routine tool in clinical medicine has significant financial and psychosocial benefits versus routine outpatient clinics. There are very few reports of telemedicine use in routine outpatient teleconsultations in the available neurosurgical literature; those that are present do not differentiate or analyze the use in routine versus emergency neurosurgery. We discuss the role of this underused resource in the developing countries and retrospectively analyze the clinical data in more than 1500 patients and 3000 teleconsultations during a period of 6 years. We address the financial implications, psychosocial factors, and several other factors that could make this relatively modest technology an indispensible tool in current neurosurgical practice, especially in a developing country like India.14 page(s