X-ray diffraction study on Cu-Pd and Cu-Pt alloys

Thesis (Ph.D. in Engineering)--University of Tsukuba, (A), no. 1237, 1994.3.2

Little Higgs after the little one

At the LHC, the Littlest Higgs Model with $T$-parity is characterised by various production channels. If the $T$-odd quarks are heavier than the exotic partners of the $W$ and the $Z$, then associated production can be as important as the pair-production of the former. Studying both, we look for final states comprising at least one lepton, jets and missing transverse energy. We consider all the SM processes that could conspire to contribute as background to our signals, and perform a full detector level simulation of the signal and background to estimate the discovery potential at the current run as well as at the scheduled upgrade of the LHC. We also show that, for one of the channels, the reconstruction of two tagged $b$-jets at the Higgs mass $(M_h = 125~{\rm GeV})$ provides us with an unambiguous hint for this model.Comment: 22 pages, 3 captioned figures, 8 Tables; minor modifications, version published in JHE

Targeting Estrogen Receptor Sites in Human Breast Cancer Cell Line T47D With Copper Conjugates of Nonsteriodal Anti-inflammatory Drug Derivatives: Antiproliferative Activity of Ketoprofen Derivative and its Copper Complex

A square planar copper complex of derivatized NSAID drug (Ketoprofen thiosemicarbazone [3-benzoyl-α-methyl benzene acetic acid thiosemicarbazone]), is characterized by elemental analysis, spectroscopy, electrochemistry and magnetic susceptibility studies which exhibits dose-dependent and enhanced antiproliferative effects on human breast cancer cell line T47D rich in progesterone receptors

Anti-inflammatory and analgesic activities of imidazolyl triazolo hydroxamic acid derivatives

280-285Hydroxamic acids are directly related with cancer and its progression. Long term exposure with inflammatory responses, dysplasia develops which leads to cancer. Metastasis of cancer and expression of transient potential receptor ankyrin-1 are known to cause severe pain. Here, we explored the possibility of developing newer hydroxamic acid derivatives as anti-inflammatory and analgesic agent. Animals were administered with 100 mg/kg dose of the synthesized imidazolyl triazolo hydroxamic acid derivatives (FP1-FP12) and 50 mg/kg dose of standard diclofenac sodium. Carrageenan induced rat paw edema and Eddy’s hot plate methods were considered for anti-inflammatory and analgesic activities. Among all the synthesized molecules, FP10 and FP4 were the most effective anti-inflammatory and analgesic agent, respectively. The activity profile of remaining molecules as anti-inflammatory agents was as follows: FP4>FP9> FP8> FP2 and as analgesic activity profile was FP10>FP3>FP8 >FP11 >FP2 > FP12. Presence of ethyl- benzyl and furan groups in linker portion of the structure minimized both the anti-inflammatory and analgesic activities. Results have shown that compounds with electron releasing groups considerably enhance both anti-inflammatory and analgesic activities