30 research outputs found
Acute toxicity and antioxydant property of Striga hermonthica (Del.) Benth (Scrophulariaceae)
Plants containing flavonoids have been reported to possess strong antioxidant properties. The aqueous acetone extract of Striga hermonthica was further separated into aqueous and ethyl acetate fractions and assayed for their in vitro antioxidant properties using 2,2-diphenyl-1-picrylhydrazyl (DPPH). Thecrude extract exhibits a weak antioxidant activity (IC50 of 95.27±2.30 ìg/ml) and an insignificant acute toxicity on mice (LD50: 1753±44 mg/kg). Luteolin was isolated and identified by mean of its spectral data as the main DPPH radical scavenger of the ethyl acetate fraction, exhibiting an IC50 value of 6.80±1.46 ìg/ml. These results suggest an antioxidant potential for S. hermonthica
Use of Efflux Pump Inhibitors (EPIs) to overcome bacterial Multi-Drug Resistance (MDR): plants as a source of chemodiversity and their adaptive response toward bacterial stress
International audienc
Evaluation of natural phenolic compounds from Clusiaceae as P-glycoprotein inhibitors
International audienc
A new isoflavone from Genista saharae (Fabaceae)
International audienc
Modulation of multi-drug-resistance (MDR) in Staphylococcus aureus by Osha (Ligusticum porteri L., Apiaceae) essential oil compounds
International audienc