Like-Triple Diabetes as First Manifestation of MODY2 in an Overweight Teenager With Transient Multiple Antibodies. Diabetes Care 2014; 37: e66-e67

Ctr Referencia Estadual Assistencia Ao Diabet & E, Salvador, BA, BrazilUniversidade Federal de São Paulo, Ctr Diabet, São Paulo, BrazilUniversidade Federal de São Paulo, Ctr Diabet, São Paulo, BrazilWeb of Scienc

Diabetes Mellitus em uma criança indígena do Amazonas

CONTEXT: Although type 2 diabetes has been described among American Indian children, no case of type 1 diabetes has been reported in the literature. CASE REPORT: We report the first case of diabetes in a South American Indian child from the tropical rainforest, who was positive for IA2 autoantibodies and genetic markers of susceptibility to type 1 diabetes, but also demonstrated residual beta cell function four years after diagnosis.CONTEXTO: O diabetes mellitus tipo 2 tem sido descrito em populações indígenas, mas casos de diabetes mellitus tipo 1 são raros e muitas vezes não bem caracterizados, devido às condições inerentes ao meio em que habitam os índios. RELATO DE CASO: Nós relatamos aqui o primeiro caso de diabetes do tipo 1 em uma criança indígena da América do Sul, proveniente da floresta Amazônica, caracterizado por marcadores genéticos, imunológicos e clínicos, mas que apresentava função residual das células beta após quatro anos do diagnóstico, o que pode dificultar, às vezes, a caracterização clínica do tipo especifico de diabetes em algumas populações.Universidade Federal de São Paulo (UNIFESP) Escola Paulista de Medicina Diabetes CenterUNIFESP, EPM, Diabetes CenterSciEL

Hemiagenesis of the thyroid gland and T3 hyperthyroidism

ESCOLA PAULISTA MED,DEPT MED,DIV ENDOCRINOL,BR-04023 SAO PAULO,SP,BRAZILESCOLA PAULISTA MED,DEPT MED,DIV ENDOCRINOL,BR-04023 SAO PAULO,SP,BRAZILWeb of Scienc

Prevalence of maturity-onset diabetes of the young mutations in Brazilian families with autosomal-dominant early-onset type 2 diabetes

Universidade Federal de São Paulo, Dept Internal Med Endocrinol, São Paulo, BrazilINSERM U342, Paris, FranceFdn Jean Dausset, CEPH, Paris, FranceUniversidade Federal de São Paulo, Dept Internal Med Endocrinol, São Paulo, BrazilWeb of Scienc

The Costs of Type 2 Diabetes Mellitus Outpatient Care in the Brazilian Public Health System

Objective: the prevalence of type 2 diabetes has shown a significant increase in parallel with health care costs. the objective of the Brazilian Study on Diabetes Costs (ESCUDI study) was to estimate direct and indirect costs of type 2 diabetes outpatient care in the Brazilian Public Health Care System. Methods: Data were collected from different levels of health care in eight Brazilian cities in 2007. A total of 1000 outpatients were interviewed and had their medical records data analyzed. Direct medical costs included expenses with medications, diagnostic tests, procedures, blood glucose test strips, and office visits. Nonmedical direct costs included expenses with diet products, transportation, and caregivers. Absenteeism, sick leave, and early retirement were classified as indirect costs. Results: Total annual cost for outpatient care was US$2108 per patient, out of which US$1335 per patient of direct costs (63.3%) and US$773 per patient of indirect costs (36.7$3199 per patient) compared to those with either microvascular (US$2062 per patient) or macrovascular (US$2517 per patient) complications only. the greatest portion of direct costs was attributed to medication (48.2%). Conclusions: Diabetes treatment leads to elevated costs both to Brazilian Public Health Care System and society. Costs increased along with duration of disease, level of care and presence of chronic complications, which suggested a need to reallocate health resources focusing on primary prevention of diabetes and its complications