Reasons for blood donation deferral in sub-Saharan Africa: experience in Ivory Coast.

IntroductionBlood donor selection is important to ensure the safety of both donors and recipients. There is a paucity of data on reasons for blood donor deferral in Ivory Coast. The aim of this study was to identify the reasons for predonation deferral at a blood collection site at General Hospital, Yopougon Attié in Abidjan.Materials and methodsThe investigators conducted a retrospective audit of data pertaining to donor deferral for blood donors that presented to the general hospital of Yopugon Attié from January 1, 2006 to December 31, 2008.ResultsA total of 10,694 prospective blood donors, presented over the study period, and 24,363 attempts to donate were registered. The majority were repeat blood donors (77.4%). A total of 2618 (10.8%) donors were deferred. The most frequent reason for deferral was a low hemoglobin level (42.5%), with females constituting the majority of those deferred. The second most frequent reason for deferral was a reported change of or new sexual partner (34.3%); male donors were predominant in this group. Additional reasons for deferral included short interdonation interval (4.6%) and reactivity for a screened biomarker (2.3%).ConclusionAlthough the rates for permanent and temporary deferral rates are similar between the Ivory Coast and high-middle income countries, the causes and demographics differ. The reasons for exclusion are preventable through awareness and education of prospective blood donors

Reasons for blood donation deferral in sub-Saharan Africa: experience in Ivory Coast.

IntroductionBlood donor selection is important to ensure the safety of both donors and recipients. There is a paucity of data on reasons for blood donor deferral in Ivory Coast. The aim of this study was to identify the reasons for predonation deferral at a blood collection site at General Hospital, Yopougon Attié in Abidjan.Materials and methodsThe investigators conducted a retrospective audit of data pertaining to donor deferral for blood donors that presented to the general hospital of Yopugon Attié from January 1, 2006 to December 31, 2008.ResultsA total of 10,694 prospective blood donors, presented over the study period, and 24,363 attempts to donate were registered. The majority were repeat blood donors (77.4%). A total of 2618 (10.8%) donors were deferred. The most frequent reason for deferral was a low hemoglobin level (42.5%), with females constituting the majority of those deferred. The second most frequent reason for deferral was a reported change of or new sexual partner (34.3%); male donors were predominant in this group. Additional reasons for deferral included short interdonation interval (4.6%) and reactivity for a screened biomarker (2.3%).ConclusionAlthough the rates for permanent and temporary deferral rates are similar between the Ivory Coast and high-middle income countries, the causes and demographics differ. The reasons for exclusion are preventable through awareness and education of prospective blood donors

Biological quality evaluation of samples stored in biobank of Pasteur Institute of Côte d'Ivoire : case of influenza in nasopharyngeal and meningococcal in cerebrospinal fluid (CSF) samples

The preservation and use of biological samples for therapy, diagnosis and research have been common practice for a long time. To maintain the stability of biomolecules (DNA, RNA, proteins) contained in the samples stored at the biobank of Pasteur Institute of Côte d'Ivoire, we evaluated the quality of the conservation of influenza nasopharyngeal and meningococcal CSF samples. Two (2) samples were chosen for this evaluation, namely Influenza A nasopharyngeal samples and Streptococcus pneumoniae CSF samples. After a few years of storage, these same samples were used to perform a PCR test. The results of the PCR tests showed a discordance of 36.4% for the Streptococcus pneumoniae CSF samples compared to 15.4% for the nasophryngeal samples. This study validates the need to write procedures for sample conservation at the level of the analysis laboratories and the Biobank. Therefore, a reflection must be carried out to standardise conservation techniques and a sample conservation evaluation programme