Caractérisation agropédologique des sols de mboltime dans la zone des niayes (Sénégal)

L'objectif de cette étude était de faire une évaluation de la fertilité physico-chimique de différents sols du village de Mboltime et de déterminer les similarités relatives. Les horizons de cinq fosses pédologiques (P1 , P2, P3, P4 et P5) ouvertes dans les zones dunaires et inter-dunaires ont servi à cet effet. Les résultats obtenus ont montré que les horizons de surface sont sableux à sablo-limoneux avec des pH et conductivité électrique variant selon les profils et les horizons. Seul le profil P4 a montré des sols acides et salés au niveau des horizons P4H1, P4H3 et P4H5. Les autres profils ont montré des sols neutres à légèrement alcalins et non salins. Les teneurs en matière organique et azote total ont été assez faibles dans les profils 1, 2, 3 et 5, et moyens dans le profil 4 avec un rapport C/N variant de 2,72 à 16,50. Les teneurs en Ca2+, Mg2+, Na+ et K+ varient suivant le C et N. Le cation le plus abondant dans les sols a été le Ca2+; suivi du Mg2+ et du Na+ alors que K+ a été le cation le moins abondant. L'analyse factorielle des correspondances (AFC) a permis de mettre en évidence deux groupes de sols en fonction de la salinité et de l'acidité. Un groupe I constitué de sols très salins et un groupe II constitué de sols non salins. Cette étude a mis en évidence deux contraintes majeures à la production végétale dans le village de Mboltime que sont la salinité et l'acidité des sols.Mots clés : Sol, Profil pédologique, Niayes, salinite ; Sénégal AGROPEDOLOGICAL CARACTERIZATION OF MBOLTIME SOILS IN NIAYES AREA (SENEGAL)The objective of this study was to evaluate physico - chemical properties of different soils from Mboltime village and relevant similarities. Horizons of five soil profiles (P1, P2, P3, P4 and P5) in the dune and inter-dune areaswere used for that purpose. The results showed variance in topsoil contents of sand with silt- loam, pH and electric conductivity according to the  profiles. Only the P4 profile presents acid and salty soil to the level asof horizons P4H1, P4H3 and P4H5. The other profiles presented neutral to slightly alkaline soil pH with limited salinity. The soil contents of organic matter, and total nitrogen were rather weak in the profiles 1, 2, 3 and 5, and moderate in profile 4. The C/N ratio values varied from 2.72 to 16.50 while soil contents of Ca2+, Mg2+, Na+ and K+ variations were according to C and N. The most abundant cations in land was Ca2+; followed by Mg2+, Na+ and K+ was the least abundant cationin soils. The factorial  correspondence analysis (FCA) showed two groups of soil according to  salinity and acidity mainly depending to high and low salinity respectively. This study showed two major constraints to land productivity in the village of Mboltime which are the salinity and the acidity of soils.Keywords : Soil, soil profile, salinity, Niayes, Senega

Influence de la litière foliaire de cinq espèces végétales tropicales sur la diversité floristique des herbacées dans la zone du Ferlo (Senegal)

L’objectif de cette étude a été d’évaluer l’effet de la présence de cinq plantes ligneuses: Balanites aegyptiaca (L.) Del., Acacia tortilis subsp. raddiana (Savi) Brenan, Acacia senegal (L.) Willd, Boscia senegalensis (Pers.) Lam. ex Poir. et Sclerocarya birrea (A. Rich.) Hochst. sur la diversité spécifique de la végétation herbacée dans le Ferlo, au Nord-Sénégal. Il a été procédé à un inventaire des espèces herbacées sous couvert et hors couvert des plantes ligneuses. Ensuite, une analyse floristique qualitative (familles, genres et espèces) a été réalisée à partir de la liste floristique des différents inventaires. Cette analyse a été couplée à une approche quantitative en utilisant le coefficient de similitude de Sørensen qui a servi à définir l’indice de diversité beta. Les résultats de l’inventaire floristique ont permis de dénombrer 28 espèces herbacées réparties dans 25 genres et 15 familles. Les plantes ligneuses comme B. senegalensis, B. aegyptiaca et S. birrea possèdent la flore la plus riche avec 18 espèces chacune, alors que A. tortilis et A. senegal ont respectivement 12 et 9 espèces. Le témoin est le moins diversifié avec 6 espèces herbacées. Parmi les herbacées, Aristida mutabilis est la plus fréquente contrairement à Achyranthes aspera, Aristida adsentionis, Chloris barbata, Cleome  viscosa, Cyperus esculentus, Datura metel, Eragrostis pilosa et Indigofera hirsuta qui sont les espèces les moins fréquentes. Les résultats de l’AFC ont montré quatre groupements végétaux. Un premier groupement qui regroupe B. senegalensis, A. raddiana et le témoin, un groupement à B. aegyptiaca, un groupement à A. senegal et enfin un groupement à S. birrea. Cette étude a permis de mettre en évidence la valeur de la présence de l’arbre dans un système de production fortement dégradé.Mots clés: Sénégal, Ferlo, interaction arbre - herbe, AFC, diversité floristique

The precarious supply of physical therapists across Canada: exploring national trends in health human resources (1991 to 2005)

<p>Abstract</p> <p>Background</p> <p>Health Human Resource (HHR) ratios are one measure of workforce supply, and are often expressed as a ratio in the number of health professionals to a sub-set of the population. In this study, we explore national trends in HHR among physical therapists (PTs) across Canada.</p> <p>Methods</p> <p>National population data were combined with provincial databases of registered physical therapists in order to estimate the HHR ratio in 2005, and to establish trends between 1991 and 2005.</p> <p>Results</p> <p>The national HHR ratio was 4.3 PTs per 10,000 population in 1991, which increased to 5.0 by 2000. In 2005, the HHR ratios varied widely across jurisdictions; however, we estimate that the national average dropped to 4.8 PTs per 10,000. Although the trend in HHR between 1991 and 2005 suggests positive growth of 11.6%, we have found negative growth of 4.0% in the latter 5-years of this study period.</p> <p>Conclusion</p> <p>Demand for rehabilitation services is projected to escalate in the next decade. Identifying benchmarks or targets regarding the optimal number of PTs, along with other health professionals working within inter professional teams, is necessary to establish a stable supply of health providers to meet the emerging rehabilitation and mobility needs of an aging and increasingly complex Canadian population.</p

Magnetism and its microscopic origin in iron-based high-temperature superconductors

High-temperature superconductivity in the iron-based materials emerges from, or sometimes coexists with, their metallic or insulating parent compound states. This is surprising since these undoped states display dramatically different antiferromagnetic (AF) spin arrangements and N$\rm \acute{e}$el temperatures. Although there is general consensus that magnetic interactions are important for superconductivity, much is still unknown concerning the microscopic origin of the magnetic states. In this review, progress in this area is summarized, focusing on recent experimental and theoretical results and discussing their microscopic implications. It is concluded that the parent compounds are in a state that is more complex than implied by a simple Fermi surface nesting scenario, and a dual description including both itinerant and localized degrees of freedom is needed to properly describe these fascinating materials.Comment: 14 pages, 4 figures, Review article, accepted for publication in Nature Physic

A Novel Recombinant Peste des Petits Ruminants-Canine Adenovirus Vaccine Elicits Long-Lasting Neutralizing Antibody Response against PPR in Goats

BACKGROUND: Peste des petits ruminants (PPR) is a highly contagious infectious disease of goats, sheep and small wild ruminant species with high morbidity and mortality rates. The Peste des petits ruminants virus (PPRV) expresses a hemagglutinin (H) glycoprotein on its outer envelope that is crucial for viral attachment to host cells and represents a key antigen for inducing the host immune response. METHODOLOGY/PRINCIPAL FINDINGS: To determine whether H can be exploited to generate an effective PPRV vaccine, a replication-competent recombinant canine adenovirus type-2 (CAV-2) expressing the H gene of PPRV (China/Tibet strain) was constructed by the in vitro ligation method. The H expression cassette, including the human cytomegalovirus (hCMV) promoter/enhancer and the BGH early mRNA polyadenylation signal, was inserted into the SspI site of the E3 region, which is not essential for proliferation of CAV-2. Infectious recombinant rCAV-2-PPRV-H virus was generated in transfected MDCK cells and used to immunize goats. All vaccinated animals produced antibodies upon primary injection that were effective in neutralizing PPRV in vitro. Higher antibody titer was obtained following booster inoculation, and the antibody was detectable in goats for at least seven months. No serious recombinant virus-related adverse effect was observed in immunized animals and no adenovirus could be isolated from the urine or feces of vaccinated animals. Results showed that the recombinant virus was safe and could stimulate a long-lasting immune response in goats. CONCLUSIONS/SIGNIFICANCE: This strategy not only provides an effective PPR vaccine candidate for goats but may be a valuable mean by which to differentiate infected from vaccinated animals (the so-called DIVA approach)

Liver Stiffness Measurement and Biochemical Markers in Senegalese Chronic Hepatitis B Patients with Normal ALT and High Viral Load

Despite the high prevalence of chronic hepatitis B (CHB) in Africa, few studies have been performed among African patients. We sought to evaluate liver stiffness measurement by FibroScan® (LSM) and two biochemical scores (FibroTest®, Fibrometer®) to diagnose liver fibrosis in Senegalese CHB patients with HBV plasma DNA load ≥3.2 log(10) IU/mL and normal alanine aminotransferase (ALT) values.LSM and liver fibrosis biochemical markers were performed on 225 consecutive HBV infected Senegalese patients with high viral load. Patients with an LSM range between 7 and 13 kPa underwent liver biopsy (LB). Two experienced liver pathologists performed histological grading using Metavir and Ishak scoring.225 patients were evaluated (84% male) and LB was performed in 69 patients, showing F2 and F3 fibrosis in 17% and 10% respectively. In these patients with a 7-13 kPa range of LSM, accuracy for diagnosis of significant fibrosis according to LB was unsatisfactory for all non-invasive markers with AUROCs below 0.70. For patients with LSM values below 7 kPa, FibroTest® (FT), and Fibrometer® (FM) using the cut-offs recommended by the test promoters suggested a fibrosis in 18% of cases for FT (8% severe fibrosis) and 8% for FM. For patients with LSM values greater than 13 kPa, FT, FM suggested a possible fibrosis in 73% and 70%, respectively.In highly replicative HBV-infected African patients with normal ALT and LSM value below 13 kPa, FibroScan®, FibroTest® or Fibrometer® were unsuitable to predict the histological liver status of fibrosis

Anisotropic three-dimensional magnetism in CaFe2As2

Inelastic neutron scattering measurements of the magnetic excitations in CaFe2As2 indicate that the spin wave velocity in the Fe layers is exceptionally large and similar in magnitude to the cuprates. However, the spin wave velocity perpendicular to the layers is at least half as large that in the layer, so that the magnetism is more appropriately categorized as anisotropic three-dimensional, in contrast to the two-dimensional cuprates. Exchange constants derived from band structure calculations predict spin wave velocities that are consistent with the experimental data

Anti-malarial prescriptions in three health care facilities after the emergence of chloroquine resistance in Niakhar, Senegal (1992–2004)

<p>Abstract</p> <p>Background</p> <p>In the rural zone of Niakhar in Senegal, the first therapeutic failures for chloroquine (CQ) were observed in 1992. In 2003, the national policy regarding first-line treatment of uncomplicated malaria was modified, replacing CQ by a transitory bi-therapy amodiaquine/sulphadoxine-pyrimethamine (AQ/SP), before the implementation of artemisinin-based combination therapy (ACT) in 2006.</p> <p>The aims of the study were to assess the evolution of anti-malarial prescriptions in three health care facilities between 1992 and 2004, in parallel with increasing CQ resistance in the region.</p> <p>Methods</p> <p>The study was conducted in the area of Niakhar, a demographic surveillance site located in a sahelo-sudanese region of Senegal, with mesoendemic and seasonal malaria transmission. Health records of two public health centres and a private catholic dispensary were collected retrospectively to cover the period 1992–2004.</p> <p>Results</p> <p>Records included 110,093 consultations and 292,965 prescribed treatments. Twenty-five percent of treatments were anti-malarials, prescribed to 49% of patients. They were delivered all year long, but especially during the rainy season, and 20% of patients with no clinical malaria diagnosis received anti-malarials. Chloroquine and quinine represented respectively 55.7% and 34.6% of prescribed anti-malarials. Overall, chloroquine prescriptions rose from 1992 to 2000, in parallel with clinical malaria; then the CQ prescription rate decreased from 2000 and was concomitant with the rise of SP and the persistence of quinine use. AQ and SP were mainly used as bi-therapy after 2003, at the time of national treatment policy change.</p> <p>Conclusion</p> <p>The results show the overall level of anti-malarial prescription in the study area for a considerable number of patients over a large period of time. Even though resistance to CQ rapidly increased from 1992 to 2001, no change in CQ prescription was observed until the early 2000s, possibly due to the absence of an obvious decrease in CQ effectiveness, a lack of therapeutic options or a blind follow-up of national guidelines.</p

Failure to Recognize Nontuberculous Mycobacteria Leads to Misdiagnosis of Chronic Pulmonary Tuberculosis

BACKGROUND: Nontuberculous mycobacterial (NTM) infections cause morbidity worldwide. They are difficult to diagnose in resource-limited regions, and most patients receive empiric treatment for tuberculosis (TB). Our objective here is to evaluate the potential impact of NTM diseases among patients treated presumptively for tuberculosis in Mali. METHODS: We re-evaluated sputum specimens among patients newly diagnosed with TB (naïve) and those previously treated for TB disease (chronic cases). Sputum microscopy, culture and Mycobacterium tuberculosis drug susceptibility testing were performed. Identification of strains was performed using molecular probes or sequencing of secA1 and/or 16S rRNA genes. RESULTS: Of 142 patients enrolled, 61 (43%) were clinically classified as chronic cases and 17 (12%) were infected with NTM. Eleven of the 142 (8%) patients had NTM disease alone (8 M. avium, 2 M. simiae and 1 M. palustre). All these 11 were from the chronic TB group, comprising 11/61 (18%) of that group and all were identified as candidates for second line treatment. The remaining 6/17 (35.30%) NTM infected patients had coinfection with M. tuberculosis and all 6 were from the TB treatment naïve group. These 6 were candidates for the standard first line treatment regimen of TB. M. avium was identified in 11 of the 142 (8%) patients, only 3/11 (27.27%) of whom were HIV positive. CONCLUSIONS: NTM infections should be considered a cause of morbidity in TB endemic environments especially when managing chronic TB cases to limit morbidity and provide appropriate treatment