226 research outputs found

    Erythema ab igne

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    Experimental investigation on an air tubular absorber enhanced with Raschig Rings porous medium in a solar furnace

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    An experimental study was carried out to assess the performance of a tubular absorber enhanced with Raschig Rings (RR) porous medium for CSP applications. Two alternative designs with different porous lengths of 20 and 40 mm were fabricated and compared with two conventional tube designs with and without surface coating. Several tests were conducted at the solar furnace SF60 of the Plataforma Solar de Almeria (PSA) within the international access program of the SFERA III project, financed by the EU. The main scope of the study was to provide comprehensive detail on the hydraulic and thermal characteristics of the modified tube for further optimization and deployment in point-focusing solar systems. Therefore, evaluations were directed to determine the effects of each design on the pressure losses and the tube wall temperature, as well as on the useful heat gain. Results indicated that although the porous inserts rise the pressure losses through the fluid flow, the higher wetted area in the porous zone for heat transfer between the air and the heated plate reduces the wall tem-perature significantly. Moreover, applying the PYROMARK 2500 as the surface coating has a high influence on increasing solar absorption and reducing thermal losses. Further investigations revealed that the integration of the porous medium changes the temperature profile formed all over the tube, transforming a Gaussian shape in the plain pipes to a spline shape with two peaks in the modified tubes. Increasing the energy and exergy effi-ciencies of the solar absorber up to 30-50% and 60-70%, respectively, demonstrated the improving effects of the proposed porous material for future applications in the solar industry

    Test and modeling of the hydraulic performance of high-efficiency cooling configurations for gyrotron resonance cavities

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    The design and manufacturing of different full-size mock-ups of the resonance cavity of gyrotrons, relevant for fusion applications, were performed according to two different cooling strategies. The first one relies on mini-channels, which are very promising in the direction of increasing the heat transfer in the heavily loaded cavity, but which could face an excessively large pressure drop, while the second one adopts the solution of Raschig rings, already successfully used in European operating gyrotrons. The mock-ups, manufactured with conventional techniques, were hydraulically characterized at the Thales premises, using water at room temperature. The measured pressure drop data were used to validate the corresponding numerical computational fluid dynamics (CFD) models, developed with the commercial software STAR-CCM+ (Siemens PLM Software, Plano TX, U.S.A.) and resulting in excellent agreement with the test results. When the validated models were used to compare the two optimized cooling configurations, it resulted that, for the same water flow, the mini-channel strategy gave a pressure drop was two-fold greater than that of the Raschig rings strategy, allowing a maximum flow rate of 1 × 10–3 m3/s to meet a maximum allowable pressure drop of 0.5 MPa

    Corn Silage Yield and Quality, and Soil Health Metrics After Fall Cover Crop Grazing

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    Integrated crop-livestock systems can potentially produce more product per unit of land with minimal impacts on soil health and cash crop quality. In the Upper Midwest there is an opportunity to graze fall cover crops (CC) after winter wheat in a corn-wheat rotation. In East Lansing, Michigan, two CC treatments: 1) a pure brassica mixture (PURE), and 2) a complex mixture containing legumes, warm and cool season grasses, and brassicas (MIX) were planted after wheat, and grazed by lambs in the fall seasons of 2019 to 2021. The following year, soil health, corn yield and quality were measured from plots corresponding to a non-grazed control and plots grazed in October, November, and December. There was no significant effect on spring soil bulk density and penetration resistance (PR) regardless of CC mixture or the timing of grazing, although PR was numerically higher in the grazed plots. Corn crude protein, acid detergent fiber, and neutral detergent fiber were not different across graze date or CC treatments (P \u3e 0.05), although corn contained more starch when grown after MIX grazed in November (P=0.02). The difference in starch was possibly an artifact of spatial variability across the site. Corn dry matter yield was lower in the non-grazed control (15.35 Mg ha-1) when compared to the grazing treatments in October (17.37 Mg ha-1) and December (17.19 Mg ha-1) (P=0.03). Grazing cover crops in the fall may improve corn yield the following year without causing soil compaction or changing corn quality

    Supercritical CO2 Extraction of Phytocompounds from Olive Pomace Subjected to Different Drying Methods

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    Olive pomace is a semisolid by-product of olive oil production and represents a valuable source of functional phytocompounds. The valorization of agro-food chain by-products represents a key factor in reducing production costs, providing benefits related to their reuse. On this ground, we herein investigate extraction methods with supercritical carbon dioxide (SC-CO2) of functional phytocompounds from olive pomace samples subjected to two different drying methods, i.e., freeze drying and hot-air drying. Olive pomace was produced using the two most common industrial olive oil production processes, one based on the two-phase (2P) decanter and one based on the three-phase (3P) decanter. Our results show that freeze drying more efficiently preserves phytocompounds such as α-tocopherol, carotenoids, chlorophylls, and polyphenols, whereas hot-air drying does not compromise the β-sitosterol content and the extraction of squalene is not dependent on the drying method used. Moreover, higher amounts of α-tocopherol and polyphenols were extracted from 2P olive pomace, while β-sitosterol, chlorophylls, and carotenoids were more concentrated in 3P olive pomace. Finally, tocopherol and pigment/polyphenol fractions exerted antioxidant activity in vitro and in accelerated oxidative conditions. These results highlight the potential of olive pomace to be upcycled by extracting from it, with green methods, functional phytocompounds for reuse in food and pharmaceutical industries

    Evaluation of chronic toxicity and carcinogenesis in rodents with the synthetic analgesic, tilidine fumarate

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    The carcinogenic potential of tilidine fumarate, a synthetic analgesic, was studied for 80 and 104 weeks in mice and rats, respectively. Groups of 50 albino CF1 mice and 65 albino Wistar rats of each sex received tilidine fumarate-lactose blend (1:1) at doses of 100, 40 and 16 mg/kg. The control groups consisted of 100 mice and 115 rats of each sex and received the lactose vehicle only. Treatment-related non-neoplastic changes consisted of reversible, increased cytoplasmic eosinophilia of hepatocytes in high and mid dose rats corresponding to areas of proliferating smooth endoplasmic reticulum; and an increased in high dose rats of proliferative or cystic lesions of the biliary epithelium. Adequate survival rates allowed stringent statistical analysis of neoplasia. Tilidine did not evoke increased tumor incidences or changes in teh average latency or onset of tumors in either species. The most frequent tumors represented spontaneous neoplasia characteristic of historical background incidence in these strains. In mice, the only statistically significant (P P < 0.01) decreased incidences of mammary fibroadenoma and pituitary adenoma. From these data, it was concluded that the synthetic analgesic tilidine does not possess tumorigenic potential in rodents.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/26174/1/0000253.pd

    Calibration of the KIT test setup for the cooling tests of a gyrotron cavity full-size mock-up equipped with mini-channels

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    In high-power fusion gyrotrons, the maximum heat-load on the wall of the interaction section is in the order of 2 kW/cm2, which is the major limiting technological factor for output power and pulse-length of the tube. The ongoing gyrotron development demands a very effective cavity cooling system for optimum gyrotron operation. In this work, the experimental investigation of a mini-channel cavity cooling using a mock-up test set-up is described. The mock-up test set-up will be used to experimentally validate the predictive simulation results and verify the mini-channel cooling performance. It is crucial for validation of the mini-channel cooling properties to determine the amount of the heat load introduced in the cavity wall by an induction heater. In order to estimate that heat load, full 3D electromagnetic simulations have been performed using the CST Studio Suite® software. A suitable calibration factor for the load deposited in the mock-up inner wall is identified after numerical investigation by a 3D thermal model. Calorimetry measurements are performed and the experimental results are compared with the simulation results obtained with a 3D thermal-hydraulic model, using the commercial software STAR-CCM+. When the calibration factor is applied, the experimental calorimetry is well reproduced by the simulations

    Olive Leaf Extract (OLE) impaired vasopressin-induced aquaporin-2 trafficking through the activation of the calcium-sensing receptor

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    Vasopressin (AVP) increases water permeability in the renal collecting duct through the regulation of aquaporin-2 (AQP2) trafficking. Several disorders, including hypertension and inappropriate antidiuretic hormone secretion (SIADH), are associated with abnormalities in water homeostasis. It has been shown that certain phytocompounds are beneficial to human health. Here, the effects of the Olive Leaf Extract (OLE) have been evaluated using in vitro and in vivo models. Confocal studies showed that OLE prevents the vasopressin induced AQP2 translocation to the plasma membrane in MCD4 cells and rat kidneys. Incubation with OLE decreases the AVP-dependent increase of the osmotic water permeability coefficient (Pf). To elucidate the possible effectors of OLE, intracellular calcium was evaluated. OLE increases the intracellular calcium through the activation of the Calcium Sensing Receptor (CaSR). NPS2143, a selective CaSR inhibitor, abolished the inhibitory effect of OLE on AVP-dependent water permeability. In vivo experiments revealed that treatment with OLE increases the expression of the CaSR mRNA and decreases AQP2 mRNA paralleled by an increase of the AQP2-targeting miRNA-137. Together, these findings suggest that OLE antagonizes vasopressin action through stimulation of the CaSR indicating that this extract may be beneficial to attenuate disorders characterized by abnormal CaSR signaling and affecting renal water reabsorption
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